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PDBsum entry 8yh5

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protein ligands Protein-protein interface(s) links
Signaling protein PDB id
8yh5

 

 

 

 

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Contents
Protein chains
336 a.a.
53 a.a.
232 a.a.
211 a.a.
271 a.a.
Ligands
ZIR
PDB id:
8yh5
Name: Signaling protein
Title: A3r-gi complex bound to i6a
Structure: Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2,guanine nucleotide-binding protein g(i) subunit alpha-1 chimera. Chain: g, a.
Source: Rattus rattus. Black rat. Organism_taxid: 10117. Gene: gnb1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Homo sapiens, bos taurus. Human, domestic cattle.
Authors: H.S.Oshima,W.Shihoya,O.Nureki
Key ref: H.S.Oshima et al. Structural insights into the agonist selectivity and structure-Based engineering of the adenosine a3 recep. To be published, . PubMed id: 39511145
Date:
27-Feb-24     Release date:   06-Nov-24    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
P62871  (GBB1_BOVIN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Bos taurus
Seq:
Struc:
340 a.a.
336 a.a.
Protein chain
P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens
Seq:
Struc:
71 a.a.
53 a.a.
Protein chain
P63097  (GNAI1_BOVIN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Bos taurus
Seq:
Struc:
354 a.a.
53 a.a.*
Protein chain
No UniProt id for this chain
Struc: 232 a.a.
Protein chain
P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens
Seq:
Struc:
71 a.a.
211 a.a.*
Protein chain
P63097  (GNAI1_BOVIN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Bos taurus
Seq:
Struc:
354 a.a.
211 a.a.
Protein chain
A0A5P9VSM6  (A0A5P9VSM6_HRSV) -  GFP from Human respiratory syncytial virus
Seq:
Struc:
239 a.a.
271 a.a.*
Protein chain
P03435  (HEMA_I75A3) -  Hemagglutinin from Influenza A virus (strain A/Victoria/3/1975 H3N2)
Seq:
Struc:
 
Seq:
Struc:
567 a.a.
271 a.a.*
Protein chain
W5QED6  (W5QED6_SHEEP) -  Adenosine receptor A3 from Ovis aries
Seq:
Struc:
317 a.a.
271 a.a.
Key:    Secondary structure
* PDB and UniProt seqs differ at 404 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains G, A: E.C.3.6.5.-  - ?????
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 

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