PDBsum entry 8y01

Structural protein

PDB id: 8y01

Contents

Protein chains

205 a.a.

339 a.a.

58 a.a.

233 a.a.

298 a.a.

Ligands

RET

PDB id:

8y01

Name:

Structural protein

Title:

Cryo-em structure of medium-wave-sensitive opsin 1

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Mutation: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Bos taurus. Domestic cattle.

Authors:

Q.Peng,H.H.Jiang,X.Y.Cheng,J.Li,J.Zhang

Key ref:

Q.Peng et al. Cryo-Em structure of medium-Wave-Sensitive opsin 1. To be published, .

Date:

21-Jan-24 Release date: 12-Feb-25

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 205 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 339 a.a.

Protein chain

P63212  (GBG2_BOVIN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Bos taurus

Seq: 71 a.a.

Struc: 58 a.a.

Protein chain

No UniProt id for this chain

Struc: 233 a.a.

Protein chain

P04001  (OPSG_HUMAN) -  Medium-wave-sensitive opsin 1 from Homo sapiens

Seq: 364 a.a.

Struc: 298 a.a.*

* PDB and UniProt seqs differ at 38 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????