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PDBsum entry 8f1c

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protein ligands metals Protein-protein interface(s) links
Transport protein PDB id
8f1c

 

 

 

 

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Contents
Protein chains
394 a.a.
Ligands
X9T ×4
POV ×4
Metals
__K ×4
_ZN ×4
PDB id:
8f1c
Name: Transport protein
Title: Voltage-gated potassium channel kv3.1 with novel positive modulator (9m)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]- 4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8h-purin-8-one (compound 4)
Structure: Potassium voltage-gated channel subfamily c member 1. Chain: a, b, c, d. Synonym: ngk2,voltage-gated potassium channel subunit kv3.1,voltage- gated potassium channel subunit kv4. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kcnc1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: expi293, human-derived. Pcdna3.1
Authors: Y.Chen,A.Ishchenko
Key ref: Y.T.Chen et al. (2023). Identification and structural and biophysical characterization of a positive modulator of human kv3 channels.. Proc natl acad sci usa, 120, 29120. PubMed id: 37812700
Date:
04-Nov-22     Release date:   25-Oct-23    
PROCHECK
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 Headers
 References

Protein chains
P48547  (KCNC1_HUMAN) -  Voltage-gated potassium channel KCNC1 from Homo sapiens
Seq:
Struc:
511 a.a.
394 a.a.
Key:    Secondary structure

 

 

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