PDBsum entry 8xgm

Membrane protein

PDB id: 8xgm

Contents

Protein chains

233 a.a.

306 a.a.

338 a.a.

233 a.a.

55 a.a.

137 a.a.

Ligands

CLR

PDB id:

8xgm

Name:

Membrane protein

Title:

Cryo-em structure of human gpr1 bound to chemerin

Structure:

Scfv16. Chain: s. Engineered: yes. G-protein coupled receptor 1. Chain: a. Synonym: chemerin-like receptor 2. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1.

Source:

Vicugna pacos. Organism_taxid: 30538. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Homo sapiens. Human. Organism_taxid: 9606. Gene: gpr1. Gene: gnb1.

Authors:

A.J.Liu,Y.Z.Liu,R.D.Ye

Key ref:

A.J.Liu and y.z.liu Cryo-Em structure of human gpr1 bound to chemerin. To be published, . PubMed id: 39466725

Date:

15-Dec-23 Release date: 21-Aug-24

Protein chain

No UniProt id for this chain

Struc: 233 a.a.

Protein chain

P46091  (GPR1_HUMAN) -  Chemerin-like receptor 2 from Homo sapiens

Seq: 355 a.a.

Struc: 306 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 338 a.a.

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 233 a.a.*

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 55 a.a.

Protein chain

Q99969  (RARR2_HUMAN) -  Retinoic acid receptor responder protein 2 from Homo sapiens

Seq: 163 a.a.

Struc: 137 a.a.

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain C: E.C.3.6.5.- - ?????