PDBsum entry 8x9t

Membrane protein

PDB id: 8x9t

Contents

Protein chains

228 a.a.

338 a.a.

55 a.a.

253 a.a.

231 a.a.

Ligands

YNH

PDB id:

8x9t

Name:

Membrane protein

Title:

Identification, structure and agonist design of an androgen membrane receptor

Structure:

Gs protein alpha subunit. Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit

Source:

Bos taurus. Organism_taxid: 9913. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: gnb1. Domestic cattle.

Authors:

Y.Q.Ping,Z.Yang

Key ref:

Z.Yang et al. Identification, Structure, And agonist design of an a membrane receptor.. Cell, . PubMed id: 39884271

Date:

01-Dec-23 Release date: 12-Feb-25

Protein chain

P04896  (GNAS2_BOVIN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms short from Bos taurus

Seq: 394 a.a.

Struc: 228 a.a.*

Protein chain

P54311  (GBB1_RAT) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Rattus norvegicus

Seq: 340 a.a.

Struc: 338 a.a.

Protein chain

P63212  (GBG2_BOVIN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Bos taurus

Seq: 71 a.a.

Struc: 55 a.a.

Protein chain

Q6QNK2  (AGRD1_HUMAN) -  Adhesion G-protein coupled receptor D1 from Homo sapiens

Seq: 874 a.a.

Struc: 253 a.a.

Protein chain

No UniProt id for this chain

Struc: 231 a.a.

* PDB and UniProt seqs differ at 52 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????