PDBsum entry 8x9s

Membrane protein

PDB id: 8x9s

Contents

Protein chains

338 a.a.

58 a.a.

268 a.a.

228 a.a.

Ligands

DHT

PDB id:

8x9s

Name:

Membrane protein

Title:

Identification, structure and agonist design of an androgen membrane receptor.

Structure:

Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2. Chain: g. Synonym: g gamma-i.

Source:

Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: gnb1. Expressed in: spodoptera frugiperda ascovirus 1a. Expression_system_taxid: 113370. Bos taurus. Domestic cattle. Organism_taxid: 9913.

Authors:

Y.Q.Ping,Z.Yang

Key ref:

Z.Yang et al. Identification, Structure, And agonist design of an a membrane receptor.. Cell, . PubMed id: 39884271

Date:

01-Dec-23 Release date: 12-Feb-25

Protein chain

P54311  (GBB1_RAT) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Rattus norvegicus

Seq: 340 a.a.

Struc: 338 a.a.

Protein chain

P63212  (GBG2_BOVIN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Bos taurus

Seq: 71 a.a.

Struc: 58 a.a.

Protein chain

Q6QNK2  (AGRD1_HUMAN) -  Adhesion G-protein coupled receptor D1 from Homo sapiens

Seq: 874 a.a.

Struc: 268 a.a.

Protein chain

P04896  (GNAS2_BOVIN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms short from Bos taurus

Seq: 394 a.a.

Struc: 228 a.a.*

* PDB and UniProt seqs differ at 52 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????