PDBsum entry 8ww2

Membrane protein

PDB id: 8ww2

Contents

Protein chains

229 a.a.

340 a.a.

55 a.a.

128 a.a.

268 a.a.

Ligands

OLA

Y01

PLM

Waters ×2

PDB id:

8ww2

Name:

Membrane protein

Title:

Gpr3/gs complex

Structure:

Guanine nucleotide-binding protein g(s) subunit alpha isoforms short. Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit

Source:

Homo sapiens. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Human. Gene: gnb1. Gene: gng2. Lama glama. Organism_taxid: 9844.

Authors:

Y.He,Y.Xiong

Key ref:

Y.Xiong et al. Identification of oleic acid as an endogenous ligand gpr3.. Cell res, . PubMed id: 38287117

Date:

24-Oct-23 Release date: 14-Feb-24

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 229 a.a.*

Protein chain

Q5JWF2  (GNAS1_HUMAN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas from Homo sapiens

Seq: 1037 a.a.

Struc: 229 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 340 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 55 a.a.

Protein chain

No UniProt id for this chain

Struc: 128 a.a.

Protein chain

P46089  (GPR3_HUMAN) -  G-protein coupled receptor 3 from Homo sapiens

Seq: 330 a.a.

Struc: 268 a.a.

* PDB and UniProt seqs differ at 199 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????