PDBsum entry 8id8

Membrane protein

PDB id: 8id8

Contents

Protein chains

225 a.a.

337 a.a.

291 a.a.

228 a.a.

56 a.a.

Ligands

YN9

PDB id:

8id8

Name:

Membrane protein

Title:

Cryo-em structure of the tug891 bound gpr120-gi complex

Structure:

Guanine nucleotide-binding protein g(i) subunit alpha-1. Chain: a. Synonym: adenylate cyclase-inhibiting g alpha protein. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Engineered: yes. Free fatty acid receptor 4.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: gnb1. Gene: ffar4, gpr120, gpr129, o3far1, pgr4. Gene: gng2.

Authors:

C.Mao,P.Xiao,X.Tao,J.Qin,Q.He,C.Zhang,X.Yu,Y.Zhang,J.Sun

Key ref:

C.Mao et al. Unsaturated bond recognition leads to biased signal i fatty acid receptor.. Science, . PubMed id: 36862765

Date:

12-Feb-23 Release date: 15-Mar-23

Protein chain

P63096  (GNAI1_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Homo sapiens

Seq: 354 a.a.

Struc: 225 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 337 a.a.

Protein chain

Q5NUL3  (FFAR4_HUMAN) -  Free fatty acid receptor 4 from Homo sapiens

Seq: 361 a.a.

Struc: 291 a.a.

Protein chain

No UniProt id for this chain

Struc: 228 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 56 a.a.

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????