PDBsum entry 8ggx

Signaling protein

PDB id: 8ggx

Contents

Protein chain

281 a.a.

Ligands

G1I

PDB id:

8ggx

Name:

Signaling protein

Title:

Locally refined cryoem structure of receptor from beta-2-adrenergic receptor in complex with gtp-bound gs heterotrimer (transition intermediate #16 of 20)

Structure:

Beta-2 adrenergic receptor. Chain: r. Synonym: beta-2 adrenoreceptor,beta-2 adrenoceptor. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: adrb2, adrb2r, b2ar. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108

Authors:

M.M.Papasergi-Scott,G.Skiniotis

Key ref:

M.M.Papasergi-Scott et al. Time-Resolved cryo-Em of g protein activation by a gp. Nature, . PubMed id: 38480881

Date:

08-Mar-23 Release date: 06-Mar-24

Protein chain

P07550  (ADRB2_HUMAN) -  Beta-2 adrenergic receptor from Homo sapiens

Seq: 413 a.a.

Struc: 281 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.?