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PDBsum entry 7hlc
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PDB id:
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Ligase
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Title:
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Pandda analysis group deposition -- crystal structure of trim21 in complex with z1079512010
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Structure:
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E3 ubiquitin-protein ligase trim21. Chain: b. Synonym: 52 kda ro protein,52 kda ribonucleoprotein autoantigen ro/ss-a,ro(ss-a),sjoegren syndrome type a antigen,ss-a,tripartite motif-containing protein 21. Engineered: yes
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Source:
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Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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1.35Å
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R-factor:
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0.184
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R-free:
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0.207
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Authors:
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Y.Kim,P.Marples,D.Fearon,F.Von Delft,S.Knapp,A.Kraemer,Structural Genomics Consortium (Sgc)
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Key ref:
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Y.Kim
et al.
Pandda analysis group deposition.
To be published,
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Date:
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04-Nov-24
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Release date:
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27-Nov-24
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PROCHECK
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Headers
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References
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Q62191
(RO52_MOUSE) -
E3 ubiquitin-protein ligase TRIM21 from Mus musculus
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Seq:
Struc:
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470 a.a.
185 a.a.*
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Key: |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 7 residue positions (black
crosses)
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Enzyme class:
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E.C.2.3.2.27
- RING-type E3 ubiquitin transferase.
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Reaction:
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S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6- ubiquitinyl-[acceptor protein]-L-lysine
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Links
