 |
|
PDB code
|
|
Protein
|
|
|
|
|
|
Structure of the n-terminal domain of cbl in complex with its binding site in zap-70
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cellular_location: cytoplasm. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(304 residues)
CATH domains:
|
|
|
|
|
|
Average nmr solution structure of the bir-2 domain of xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(117 residues)
CATH domain:
|
|
|
|
|
|
Structure of tnf receptor associated factor 2 (traf2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C, D, E, F
(168 residues)
CATH domain:
|
|
|
|
|
|
Structure of tnf receptor associated factor 2 in complex with a peptide from tnf-r2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Other_details: sequence from human tnf-r2, swiss prot accession p20333
|
|
|
Chains:
A, B, C, D, E, F
(191 residues)
CATH domain:
|
|
|
|
|
|
Structure of the c3hc4 domain by 1h-nuclear magnetic resonance spectroscopy; a new structural class of zinc-finger
|
|
|
Source: Equid herpesvirus 1. Equine herpesvirus 1. Organism_taxid: 10326
|
|
|
Chain:
A
(68 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex between the traf domain of human traf2 and an lmp1 binding peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence of this peptide naturally occurs in humans (homo sapiens)
|
|
|
Chains:
A, B, C
(168 residues)
CATH domain:
|
|
|
|
|
|
Structure of tnf receptor associated factor 2 in complex with a 17- residue cd40 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence of this peptide naturally occurs in humans (homo sapiens).
|
|
|
Chains:
A, B, C
(187 residues)
CATH domain:
|
|
|
|
|
|
Structure of tnf receptor associated factor 2 in complex with a 5- residue cd40 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence of this peptide naturally occurs in humans (homo sapiens)
|
|
|
Chains:
A, B, C, D, E, F, G, H
(168 residues)
CATH domain:
|
|
|
|
|
|
Structure of tnf receptor associated factor 2 in complex with a human cd30 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence of this peptide naturally occurs in humans (homo sapiens)
|
|
|
Chains:
A, B, C, D, E, F
(168 residues)
CATH domain:
|
|
|
|
|
|
Structure of tnf receptor associated factor 2 (traf2) in complex with a human ox40 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence of this peptide naturally occurs in humans (homo sapiens)
|
|
|
Chains:
A, B, C, D, E, F
(168 residues)
CATH domain:
|
|
|
|
|
|
Structure of tnf receptor associated factor 2 in complex with a m4-1bb peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence of this peptide naturally occurs in mouse (mus musculus)
|
|
|
Chains:
A, B, C, D, E, F
(168 residues)
CATH domain:
|
|
|
|
|
|
N-terminal ring finger domain of human not-4
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(78 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex between the n-terminal domain of tradd and the traf domain of traf2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
B
(171 residues)
CATH domain:
|
|
|
|
|
|
Average nmr solution structure of the bir-3 domain of xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(117 residues)
CATH domain:
|
|
|
|
|
|
Structure of a cbl-ubch7 complex: ring domain function in ubiquitin- protein ligases
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized. Expression_system_taxid: 562
|
|
|
Chain:
A
(388 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PRO
is 50.00% similar to
enzyme reactant protein lysine
|
|
|
|
|
|
|
Molecular basis for cd40 signaling mediated by traf3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(205 residues)
CATH domain:
|
|
|
|
|
|
Molecular basis for cd40 signaling mediated by traf3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence of this peptide occurs naturally in humans (homo sapiens)
|
|
|
Chains:
A, B
(205 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the phd domain from the kap-1 corepressor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(88 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of a 9 residue peptide from smac/diablo complexed to the bir3 domain of xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the 9 residue peptide was chemically synthesized.
|
|
|
Chain:
A
(117 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of smac bound to xiap-bir3 domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: smac. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
C, D
(89 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex of xiap-bir2 and caspase 3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: i39005. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: u32974.
|
|
|
Chains:
E, F
(111 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the xiap/caspase-7 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
C, D
(17 residues)
|
|
|
|
|
|
Crystal structure of caspase-7 complexed with xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: casp7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: xiap.
|
|
|
Chains:
E, F
(18 residues)
|
|
|
|
|
|
Ring-h2 finger domain of el5
|
|
|
Source: Oryza sativa. Rice. Organism_taxid: 4530. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(55 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of diap1-bir2
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: diap1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(96 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of diap1-bir2/grim
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: diap1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence is naturally found in drosophila melanogaster (fruit fly).
|
|
|
Chain:
A
(105 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of diap1-bir2/hid complex
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: diap1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence is naturally found in drosophila melanogaster (fruit fly).
|
|
|
Chain:
A
(102 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the brca1/bard1 ring-domain heterodimer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: bard1.
|
|
|
Chains:
A, B
(103 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the brct repeat region from the breast cancer associated protein, brca1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
X
(207 residues)
CATH domains:
|
|
|
|
|
|
Siah, seven in absentia homolog
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(190 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the caspase-7 / xiap-bir2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
C, D
(17 residues)
|
|
|
|
|
|
Downstream regulator tank binds to the cd40 recognition site on traf3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chain:
A
(192 residues)
CATH domain:
|
|
|
|
|
|
Downstream regulator tank binds to the cd40 recognition site on traf3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chain:
A
(192 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of rat brca1 tandem-brct region
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(190 residues)
CATH domains:
|
|
|
|
|
|
Traf6 apo structure
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf6. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(155 residues)
CATH domain:
|
|
|
|
|
|
Traf6-rank complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf6. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rank. Expression_system_taxid: 562
|
|
|
Chain:
A
(155 residues)
CATH domain:
|
|
|
|
|
|
Traf6-cd40 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf6. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cd40. Expression_system_taxid: 562
|
|
|
Chain:
A
(155 residues)
CATH domain:
|
|
|
|
|
|
Structure of the cul1-rbx1-skp1-f boxskp2 scf ubiquitin ligase complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
|
|
|
Chain:
B
(88 residues)
CATH domain:
|
|
|
|
|
|
Structure of the cul1-rbx1-skp1-f boxskp2 scf ubiquitin ligase complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
C
(88 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the fha domain of the chfr mitotic checkpoint protein complexed with tungstate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(113 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the fha domain of the chfr mitotic checkpoint protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(112 residues)
CATH domain:
|
|
|
|
|
|
Structural consequences of a cancer-causing brca1-brct missense mutation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
X
(207 residues)
CATH domains:
|
|
|
|
|
|
Solution structure of the u-box of prp19
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: prp19. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(56 residues)
CATH domain:
|
|
|
|
|
|
Structure of caspase-9 in an inhibitory complex with xiap-bir3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4 or api3 or iap3 or xiap. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chain:
A
(91 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the brct-c domain from human brca1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(110 residues)
CATH domain:
|
|
|
|
|
|
Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ml-iap)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7 or kiap or mliap or livin. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide was chemically synthesized
|
|
|
Chains:
A, B, C, D, E
(99 residues)
CATH domain:
|
|
|
|
|
|
Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ml-iap)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7 or kiap or mliap or livin. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide was chemically synthesized
|
|
|
Chains:
A, B, C, D, E
(99 residues)
CATH domain:
|
|
|
|
|
|
Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ml-iap)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7 or kiap or mliap or livin. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide was chemically synthesized
|
|
|
Chains:
A, B, C, D, E
(99 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of a diap1-dronc complex
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was synthesized.
|
|
|
Chains:
A, B, C, D, E, F, G, H, I, J
(94 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of a baculoviral inhibitor of apoptosis (iap) repeat
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(101 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the traf domain of traf2 in a complex with a peptide from the cd40 receptor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Other_details: sequence derived from human cd40
|
|
|
Chains:
A, B, C
(179 residues)
CATH domain:
|
|
|
|
|
|
Structurally distinct recognition motifs in lymphotoxin-b receptor and cd40 for traf-mediated signaling
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf3 or craf1 or cap1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide was chemically synthesized, the sequence of the peptide occurs naturally in humans (homo sapiens)
|
|
|
Chain:
A
(192 residues)
CATH domain:
|
|
|
|
|
|
Rag1 dimerization domain
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Cell_line: bl21. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell_line: bl21
|
|
|
Chain:
A
(116 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of human mdm2 with an imidazoline inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C
(85 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of diap1 bir1 bound to a reaper peptide
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: iap1, th. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the sequence of this peptide occurs naturally in drosophila (fruit flies).
|
|
|
Chain:
A
(97 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of diap1 bir1 bound to a grim peptide
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: iap1, th. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the sequence of this peptide occurs naturally in drosophila (fruit fly).
|
|
|
Chain:
A
(97 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the brca1 brct domains in complex with the phosphorylated interacting region from bach1 helicase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes
|
|
|
Chain:
A
(211 residues)
CATH domains:
|
|
|
|
|
|
Nmr solution structure of the u box domain from atpub14, an armadillo repeat containing protein from arabidopsis thaliana
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(78 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the brca1 brct repeats bound to a phosphorylated bach1 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide was chemically synthesized. The sequence of the peptide occurs naturally in humans
|
|
|
Chain:
A
(211 residues)
CATH domains:
|
|
|
|
|
|
Structural basis of phosphopeptide recognition by the brct domain of brca1: structure of brca1 missense variant v1809f
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(207 residues)
CATH domains:
|
|
|
|
|
|
Structural basis of phospho-peptide recognition by the brct domain of brca1, structure with phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: in vitro optimized phosphopeptide
|
|
|
Chains:
A, B, C, D, E
(208 residues)
CATH domains:
|
|
|
|
|
|
Structure of human mdm2 in complex with a benzodiazepine inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(96 residues)
CATH domain:
|
|
|
|
|
|
Structure of human mdm2 in complex with an optimized p53 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
M
(88 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of an antagonists of the xiap-caspase-9 interaction complexed to the bir3 domain of xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4, api3, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(117 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of an antagonists of the xiap-caspase-9 interaction complexed to the bir3 domain of xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4, api3, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(117 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of a complex between mdm2 and a small molecule inhibitor
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(107 residues)
CATH domain:
|
|
|
|
|
|
Structure of an ml-iap/xiap chimera bound to a 9mer peptide derived from smac
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: diablo, smac. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the cand1-cul1-roc1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: rbx1, roc1, rnf75. Gene: cand1.
|
|
|
Chain:
B
(88 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of rsgi ruh-005, a pdz domain in human cdna, kiaa1095
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa1095. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(107 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of wwe domain in bab28015
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ak012080. Other_details: in vitro translation. Cell free synthesis
|
|
|
Chain:
A
(110 residues)
CATH domain:
|
|
|
|
|
|
Nmr based structural model of the ubch5b-cnot4 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chain:
B
(52 residues)
|
|
|
|
|
|
Sterile alpha motif (sam) domain of mouse bifunctional apoptosis regulator
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: riken cdna 3010001a07. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(91 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring-h2 finger domain of mouse deltex protein 2
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: riken cdna 2610524d08. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(114 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of phd domain in phd finger protein 7
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: riken cdna 1700010p14. Other_details: cell free protein synthesis
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the u-box in human ubiquitin conjugation factor e4a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna ha03786. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(98 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the fourth pdz domain of kiaa1095 protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa hk06736. Other_details: cell free protein synthesis
|
|
|
Chain:
A
(124 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the n-terminal ubiquitin-like domain in human np95/icbp90-like ring finger protein (nirf)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf2. Other_details: cell-free synthesis
|
|
|
Chain:
A
(89 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of ring finger in ring finger protein 38
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf38. Other_details: cell free protein synthesis
|
|
|
Chain:
A
(75 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of a fyve-type domain from caspase regulator carp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(91 residues)
CATH domain:
|
|
|
|
|
|
Structure of the brct repeats of brca1 bound to a ctip phosphopeptide.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Other_details: synthetic phosphopeptide
|
|
|
Chain:
A
(211 residues)
CATH domains:
|
|
|
|
|
|
Xenopus laevis mdm2 bound to the transactivation domain of human p53
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(88 residues)
CATH domain:
|
|
|
|
|
|
Mdm2 bound to the transactivation domain of p53
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of thE C-cbl tkb domain in complex with the aps ptyr-618 phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: sequence appears in rattus norvegicus, gene aps
|
|
|
Chain:
A
(304 residues)
CATH domains:
|
|
|
|
|
|
Nmr structure of unliganded mdm2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(119 residues)
CATH domain:
|
|
|
|
|
|
Np95-like ring finger protein isoform b [homo sapiens]
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(115 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the cyclophiln_ring domain of human peptidylprolyl isomerase (cyclophilin)-like 2 isoform b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ppil2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(187 residues)
CATH domain:
|
|
|
|
|
|
Lmp1 protein binds to traf3 as a structural cd40
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf3, cap1, craf1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in the latent membrane protein i of epstein barr virus
|
|
|
Chain:
A
(192 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of siah1 sbd bound to the peptide ekpaavvapittg from sip
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: siah1, humsiah. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide was chemically synthesized. The sequence of the peptide can be naturally found in homo sapiens (human)
|
|
|
Chain:
A
(146 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the tandem wwe domain of drosophila deltex
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: dx. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(160 residues)
CATH domains:
|
|
|
|
|
|
Protein-peptide complex
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthesized peptide
|
|
|
Chains:
A, B, C, D
(191 residues)
CATH domains:
|
|
|
|
|
|
Hdm2 in complex with a beta-hairpin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was synthesized.
|
|
|
Chain:
A
(92 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the prp19 u-box dimer
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: prp19, pso4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F
(56 residues)
CATH domain:
|
|
|
|
|
|
N-terminal sh3 domain of cin85 bound to cbl-b peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organ: brain, kidney, heart, placenta, lung, liver, skeletal muscle, pancreas. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
C
(11 residues)
|
|
|
|
|
|
Crystal structure of the chip u-box e3 ubiquitin ligase
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D
(281 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of the chip-ubc13-uev1a complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2n, blu. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ube2v1, croc1, ube2v, uev1, p/okcl.19. Mus musculus. Mouse.
|
|
|
Chains:
S, T, U, V
(75 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the c4 zinc-finger domain of hdm2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41.
|
|
|
Chain:
A
(46 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the c4 zinc-finger domain of hdm2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41.
|
|
|
Chain:
A
(46 residues)
CATH domain:
|
|
|
|
|
|
Solution nmr structure of the dwnn domain from human rbbp6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: (de3) plyss.
|
|
|
Chain:
A
(86 residues)
CATH domain:
|
|
|
|
|
|
N-terminal domain of cbl in complex with its binding site on zap-70
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(305 residues)
CATH domains:
|
|
|
|
|
|
Ring1b-bmi1 e3 catalytic domain structure
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
B
(96 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the RNA recognition motif of cnot4
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: cnot4. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(111 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the zf-c3hc4 domain of human kiaa1865
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna fj14303. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(93 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the fha domain of human ubiquitin ligase protein rnf8
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf8. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(145 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring domain of the non-smc element 1 protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: nse1. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(74 residues)
|
|
|
|
|
|
Solution structure of the ring domain of the tripartite motif protein 32
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim32. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(88 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the sh3 domain of the mouse hypothetical protein sh3rf2
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: sh3rf2. Other_details: cell-free system
|
|
|
Chain:
A
(70 residues)
|
|
|
|
|
|
Solution structure of the ring domain of the human cellular modulator of immune recognition protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: march8. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(80 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring domain of the human ring finger protein 146
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf146. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(71 residues)
|
|
|
|
|
|
Solution structure of the b-box domain of the human tripartite motif- containing 63 protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim63. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(64 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of rsgi ruh-049, a uba domain from mouse cdna
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: cbl. Other_details: cell-free protein synthesis
|
|
|
Chains:
A, B
(53 residues)
|
|
|
|
|
|
Solution structure of the rwd domain of human ring finger protein 25
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf25. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(128 residues)
CATH domain:
|
|
|
|
|
|
Solution structures of the fn3 domain of human tripartite motif protein 9
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim9. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(110 residues)
CATH domain:
|
|
|
|
|
|
One sequence two fold ? : correct fold of the zf-b-box domain from human tripartite motif protein 39
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim39. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(53 residues)
|
|
|
|
|
|
One sequence two fold ? : miss fold of the zf-b-box domain from human tripartite motif protein 39
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim39. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(53 residues)
|
|
|
|
|
|
Solution structure of the zz domain of zinc finger swim domain containing protein 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: zswim2. Expressed in: cell free synthesis. Other_details: cell free protein synthesis
|
|
|
Chain:
A
(98 residues)
|
|
|
|
|
|
Solution structure of the b-box domain of the human midline-2 protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mid2, fxy2, rnf60, trim1. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(84 residues)
CATH domain:
|
|
|
|
|
|
The solution structure of the first sh3 domain of mouse sh3 domain containing ring finger 2
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: sh3rf2. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(68 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the chy zinc finger domain of the ring finger and chy zinc finger domain-containing protein 1 from mus musculus
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rchy1. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(143 residues)
|
|
|
|
|
|
An extended conformation of the rwd domain of human ring finger protein 25
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf25. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(137 residues)
CATH domain:
|
|
|
|
|
|
The solution structure of the fn3 domain of human midline 2 protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mid2. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(127 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of rsgi ruh-065, a uba domain from human cdna
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb, rnf56. Other_details: cell-free protein synthesis
|
|
|
Chains:
A, B
(53 residues)
|
|
|
|
|
|
Solution structure of the mid1 b box2 chc(d/c)c2h2 zinc-binding domain: insights into an evolutionary conserved ring fold
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mid1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(47 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the filamin domain from human tripartite motif protein 45
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim45. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(113 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the phd domain in ring finger protein 107
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf2, nirf, rnf107. Other_details: cell free protein synthesis
|
|
|
Chain:
A
(77 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring domain of the human ring finger protein 4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf4. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(69 residues)
|
|
|
|
|
|
Solution structure of the ring domain of the baculoviral iap repeat- containing protein 4 from homo sapiens
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(75 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring domain of the human tnf receptor- associated factor 6 protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf6. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(86 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring domain of the human tripartite motif- containing protein 39
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim39. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(58 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring domain of the human ring-box protein 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf7. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(81 residues)
|
|
|
|
|
|
Solution structure of the ring domain of the ring finger and chy zinc finger domain-containing protein 1 from mus musculus
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rchy1. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(55 residues)
|
|
|
|
|
|
Solution structure of the zinc finger, c3hc4 type (ring finger) domain of ring finger protein 126
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rnf126. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(78 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the zinc finger, c3hc4 type (ring finger) domain of tripartite motif-containing protein 5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim5, rnf88. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the zinc finger, c3hc4 type (ring finger)" domain of tnf receptor-associated factor 3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf3. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(66 residues)
|
|
|
|
|
|
Solution structure of the zf-b_box domain from human tripartite motif protein 41
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim41. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(57 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring-finger domain from human tripartite motif protein 34
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim34, ifp1, rnf21. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(79 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of traf-type zinc finger domains (190- 248) from human tnf receptor-associated factor 4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf4, cart1, mln62, rnf83. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(66 residues)
CATH domain:
|
|
|
|
|
|
Dimerization and u-box domains of zebrafish c-terminal of hsp70 interacting protein
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Gene: stub1 (amino acids 112-284). Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(138 residues)
CATH domains:
Unassigned
Unassigned
|
|
|
|
|
|
Ubiquitin-like domain of human nuclear zinc finger protein np95
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(77 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the rbcc/trim b-box1 domain of human mid1: b-box with a ring
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mid1, fxy, rnf59, trim18, xprf. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(78 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the usp8 interaction domain of human nrdp1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf41. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(134 residues)
|
|
|
|
|
|
Key contacts promote recongnito of baff-r by traf3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf3, cap1, craf1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the sequence of this protein naturally exists in homo sapiens (human).
|
|
|
Chain:
A
(192 residues)
CATH domain:
|
|
|
|
|
|
Mdm2 in complex with an 8-mer p53 peptide analogue
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic peptide
|
|
|
Chain:
A
(88 residues)
CATH domain:
|
|
|
|
|
|
Structure of a usp8-nrdp1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp8, kiaa0055, ubpy. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: rnf41.
|
|
|
Chains:
B, D, F
(121 residues)
|
|
|
|
|
|
Structure of a bmi-1-ring1b polycomb group ubiquitin ligase complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
B
(100 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of hdm2 ring finger domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(63 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ddb1-cul4a-rbx1-sv5v complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ddb1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Simian virus 5. Organism_taxid: 11207. Gene: p/v.
|
|
|
Chain:
D
(90 residues)
CATH domain:
|
|
|
|
|
|
Structure of an ml-iap/xiap chimera bound to a 4-mer peptide (avpw)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemically synthesized peptide
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
Structure of an ml-iap/xiap chimera bound to a peptidomimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
X-ray structure of the brca1 brct mutant m1775k
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
X
(208 residues)
CATH domains:
|
|
|
|
|
|
Complex between the pryspry domain of trim21 and igg fc
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
B, E
(181 residues)
CATH domain:
|
|
|
|
|
|
Xiap bir3 bound to a smac mimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(97 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring domain of human traf6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf6, rnf85. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(63 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the uba domain from cbl-b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb, rnf56. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(44 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the human pirh2 ring-h2 domain. Northeast structural genomics consortium target ht2b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rchy1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(52 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the uba domain from c-cbl
|
|
|
Source: Homo sapiens. Human. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli.
|
|
|
Chain:
A
(56 residues)
CATH domain:
|
|
|
|
|
|
Structure of the mid1 tandem b-boxes reveals an interaction reminiscent of intermolecular ring heterodimers
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mid1, fxy, rnf59, trim18, xprf. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(101 residues)
CATH domain:
|
|
|
|
|
|
Solution nmr structure of n-terminal domain of human pirh2. Northeast structural genomics consortium (nesg) target ht2a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rchy1, arnip, chimp, pirh2, rnf199, znf363. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(137 residues)
|
|
|
|
|
|
Solution nmr structure of c-terminal domain of human pirh2. Northeast structural genomics consortium (nesg) target ht2c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rchy1, arnip, chimp, pirh2, rnf199, znf363. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(47 residues)
CATH domain:
|
|
|
|
|
|
E2-c-cbl recognition is necessary but not sufficient for ubiquitination activity
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(83 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of arkadia ring-h2 finger domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf111. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(69 residues)
|
|
|
|
|
|
Solution structure of uba domain of xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(104 residues)
CATH domain:
|
|
|
|
|
|
U-box domain of the e3 ubiquitin ligase e4b
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ube4b, ufd2. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: 6xhis-sumo tag with h3c protease cleavage site
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of e4b/ufd2a u-box domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hdnb1, kiaa0684, ube4b, ufd2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(100 residues)
CATH domain:
|
|
|
|
|
|
Solution nmr structure of zinc finger domain of e3 ubiquitin-protein ligase praja-1 from homo sapiens, northeast structural genomics consortium (nesg) target hr4710b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pja1, rnf70. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(91 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of uhrf1 tandem tudor domains in a complex with histone h3 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic. Organism_taxid: 32630
|
|
|
Chain:
A
(161 residues)
CATH domains:
|
|
|
|
|
|
Structure of ciap1 card
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api1, birc2, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(132 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of helix-ring domain of cbl-b in the tyr363 phosphorylated form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(82 residues)
CATH domain:
|
|
|
|
|
|
Structure of phd domain of uhrf1 in complex with h3 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
|
|
|
Chain:
A
(69 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of uhrf1 phd domains in a complex with histone h3 peptide
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
|
|
|
Chain:
A
(69 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of the uhrf1 phd domain
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(69 residues)
CATH domain:
|
|
|
|
|
|
Rbx1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rbx1, rnf75, roc1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: ril.
|
|
|
Chain:
A
(100 residues)
CATH domain:
|
|
|
|
|
|
Structure of the rhesus monkey trim5alpha pryspry domain
|
|
|
Source: Macaca mulatta. Rhesus macaque,rhesus macaques,rhesus monkeys. Organism_taxid: 9544. Gene: trim5. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(205 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of cxc domain of msl2
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: msl-2, cg3241. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(52 residues)
|
|
|
|
|
|
Nmr structure of mdm2 (6-125) with pip-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(125 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of ring domain of e3 ubiquitin ligase doa10
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ssm4, doa10, yil030c, yi3299.01c, yi9905.18c. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(83 residues)
CATH domain:
|
|
|
|
|
|
Phd domain from human shprh
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: shprh, kiaa2023. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(65 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of hdm2 with engineered cyclotide
|
|
|
Source: Synthetic construct. Organism_taxid: 32630. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2.
|
|
|
Chain:
B
(83 residues)
CATH domain:
|
|
|
|
|
|
Solution nmr structure of e3 ubiquitin-protein ligase zfp91 from homo sapiens, northeast structural genomics consortium (nesg) target hr7784a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fksg11, zfp91, znf757. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(89 residues)
CATH domains:
|
|
|
|
|
|
Solution nmr structure of the ring finger domain from the kip1 ubiquitination-promoting e3 complex protein 1 (kpc1/rnf123) from homo sapiens, northeast structural genomics consortium (nesg) target hr8700a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fp1477, kpc1, rnf123. Expressed in: escherichia coli. Expression_system_taxid: 469008. Other_details: plasmid
|
|
|
Chain:
A
(61 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of sumo dimer in complex with sim2-3 from rnf4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: smt3b, smt3h1, sumo3. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Mus musculus. Mouse.
|
|
|
Chain:
C
(25 residues)
|
|
|
|
|
|
Structure of complex of mdm2(3-109) and p73 tad(10-25)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: p73, tp73.
|
|
|
Chain:
A
(107 residues)
CATH domain:
|
|
|
|
|
|
Phosphotyrosine binding domain
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: cbll1, hakai. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(89 residues)
|
|
|
|
|
|
Nmr structure of the rad18-ubz/ubiquitin complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: rad18, rnf73.
|
|
|
Chain:
B
(33 residues)
|
|
|
|
|
|
Nmr structure of the ubiquitin-binding zinc finger (ubz) domain from human rad18
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rad18, rnf73. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(33 residues)
|
|
|
|
|
|
Nmr structure of the hltf hiran domain in its DNA-bound conformation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hltf, hip116a, rnf80, smarca3, snf2l3, zbu1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(122 residues)
|
|
|
|
|
|
Solution structure of rnf126 n-terminal zinc finger domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf126. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(42 residues)
|
|
|
|
|
|
Solution structure of rnf126 n-terminal zinc finger domain in complex with bag6 ubiquitin-like domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf126. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: bag6, bat3, g3.
|
|
|
Chain:
A
(42 residues)
|
|
|
|
|
|
Crystal structure of the bard1 brct domains
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bard1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(210 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of thE C-terminal domain of mouse nrdp1
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rnf41. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(123 residues)
|
|
|
|
|
|
Crystal structure of the uba domain from human c-cbl ubiquitin ligase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C
(46 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the uba domain from cbl-b ubiquitin ligase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb, rnf56. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(42 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the uba domain from cbl-b ubiquitin ligase in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb, rnf56. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Bos taurus. Cattle. Organism_taxid: 9913
|
|
|
Chain:
A
(44 residues)
CATH domain:
|
|
|
|
|
|
Smac mimic bound to bir3-xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4, api3, iap3, xiap. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(106 residues)
CATH domain:
|
|
|
|
|
|
Avpf bound to bir3-xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4, api3, iap3, xiap. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes
|
|
|
Chains:
A, B, C, D
(109 residues)
CATH domain:
|
|
|
|
|
|
Structure of the ubch5 :chip u-box complex
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Gene: ube2d1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: stub1.
|
|
|
Chains:
C, D
(72 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the sra domain of the human uhrf1 protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(197 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the fha domain of rnf8 in complex with its optimal phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf8, kiaa0646. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic phosphopeptide
|
|
|
Chain:
A
(132 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap bir1 domain (i222 form)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4, api3, iap3, xiap. Expressed in: escherichia coli k12. Expression_system_taxid: 83333.
|
|
|
Chain:
A
(78 residues)
CATH domain:
|
|
|
|
|
|
The crystal structure of tab1 and bir1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tab1, map3k7ip1. Expressed in: escherichia coli k12. Expression_system_taxid: 83333. Gene: xiap, api3, birc4, iap3.
|
|
|
Chains:
B, D
(79 residues)
CATH domain:
|
|
|
|
|
|
Structure of the yeast u-box-containing ubiquitin ligase ufd2p
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ufd2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(943 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Structure of the yeast u-box-containing ubiquitin ligase ufd2p
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ufd2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(937 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of xiap bir1 domain (p21 form)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4, api3, iap3, xiap. Expressed in: escherichia coli k12. Expression_system_taxid: 83333.
|
|
|
Chains:
D, C, B, A
(78 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the bard1 brct repeat
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bard1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(202 residues)
CATH domains:
|
|
|
|
|
|
Nmr solution structures of human kap1 phd finger-bromodomain
|
|
|
Source: Homo sapiens. Human. Gene: trim28, kap1, rnf96, tif1b. Expressed in: escherichia coli.
|
|
|
Chain:
A
(189 residues)
|
|
|
|
|
|
Complex structure of wwe in rnf146 with atp
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rnf146. Expressed in: cell-free synthesis.
|
|
|
Chain:
A
(110 residues)
CATH domain:
|
|
|
|
|
|
Chemical shift assignments for mip and mdm2 in bound state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: protein expresses as hat-gb1-(thrombin cleavage site)-mip-(tev cleavage site)-mdm2-t7tag fusion.
|
|
|
Chain:
A
(131 residues)
CATH domain:
|
|
|
|
|
|
Human bir3 domain of baculoviral inhibitor of apoptosis repeat- containing 3 (birc3)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Other_details: mammalian gene collection (mgc)
|
|
|
Chains:
A, B
(94 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the mdm2-mdmx ring domain heterodimer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, C
(60 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the mdm2-mdmx ring domain heterodimer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, C
(64 residues)
CATH domain:
|
|
|
|
|
|
Murine trim21
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(186 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap bir3 with a bivalent smac mimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(96 residues)
CATH domain:
|
|
|
|
|
|
Evolutionary basis of HIV restriction by the antiretroviral trimcyp
|
|
|
Source: Human immunodeficiency virus 1. Organism_taxid: 82834. Strain: lw12.3 isolate. Gene: gag. Expressed in: escherichia coli. Expression_system_taxid: 562. Macaca fascicularis. Crab-eating macaque. Organism_taxid: 9541.
|
|
|
Chains:
B, D
(163 residues)
CATH domain:
|
|
|
|
|
|
Ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(64 residues)
CATH domain:
|
|
|
|
|
|
C-terminal cysteine-rich domain of human chfr bound to madpr
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(213 residues)
CATH domain:
|
|
|
|
|
|
C-terminal cysteine-rich domain of human chfr bound to p(1),p(2)- diadenosine-5'-pyrophosphate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(212 residues)
CATH domain:
|
|
|
|
|
|
C-terminal cysteine rich domain of human chfr bound to amp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: codonplus ril
|
|
|
Chains:
A, B
(213 residues)
CATH domain:
|
|
|
|
|
|
C-terminal cysteine-rich domain of human chfr
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: codonplus ril
|
|
|
Chains:
A, B
(212 residues)
CATH domain:
|
|
|
|
|
|
Structure of nativE C-cbl
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F
(384 residues)
CATH domains:
|
|
|
|
|
|
Structure of c-cbl-zap-70 peptide complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, C
(377 residues)
CATH domains:
|
|
|
|
|
|
Rad18 ubiquitin ligase ring domain structure
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(89 residues)
CATH domain:
|
|
|
|
|
|
Complex of rad18 (rad6 binding domain) with rad6b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
B
(21 residues)
|
|
|
|
|
|
The idol-ube2d complex mediates sterol-dependent degradation of the ldl receptor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta.
|
|
|
Chains:
A, B
(64 residues)
CATH domain:
|
|
|
|
|
|
The idol-ube2d complex mediates sterol-dependent degradation of the ldl receptor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, C, E, G
(67 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the b-box domain from tripartite motif- containing protein 5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim5. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(59 residues)
|
|
|
|
|
|
Solution structure of the zinc finger cchc domain from the human retinoblastoma-binding protein 6 (retinoblastoma-binding q protein 1, rbq-1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rbbp6. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(55 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring domain (1-56) from tripartite motif- containing protein 31
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim31. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(63 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring domain (1-66) from tripartite motif- containing protein 31
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim31. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(73 residues)
|
|
|
|
|
|
Solution structure of the traf-type zinc finger domains (102-164) from human tnf receptor associated factor 4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf4. Other_details: cell free protein synthesis
|
|
|
Chain:
A
(76 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ring finger of human retinoblastoma-binding protein 6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rbbp6. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(74 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ms1043
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: cell-free protein synthesis
|
|
|
Chains:
A, B
(45 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human bromodomain protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: cell-free protein synthesis.
|
|
|
Chains:
A, B, C, D
(113 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the sra domain of mouse np95 in complex with hemi-methylated cpg DNA
|
|
|
Source: Synthetic: yes. Other_details: nucleotide synthesis. Mus musculus. Mouse. Organism_taxid: 10090. Gene: uhrf1, np95. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(210 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the sra domain of mouse np95 in complex with hemi-methylated cpg DNA
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: uhrf1, np95. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: nucleotide synthesis. Other_details: nucleotide synthesis
|
|
|
Chain:
A
(210 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the sra domain of mouse np95 in complex with hemi-methylated cpg DNA
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: uhrf1, np95. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: nucleotide synthesis. Other_details: nucleotide synthesis
|
|
|
Chain:
A
(209 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of unliganded sra domain of mouse np95
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: uhrf1, np95. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(190 residues)
CATH domain:
|
|
|
|
|
|
Mouse np95 sra domain DNA specific complex 1
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: np95. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic: yes
|
|
|
Chain:
B
(209 residues)
CATH domain:
|
|
|
|
|
|
Mouse np95 sra domain DNA specific complex 2
|
|
|
Source: Synthetic: yes. Mus musculus. Mouse. Organism_taxid: 10090. Gene: np95. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
B
(206 residues)
CATH domain:
|
|
|
|
|
|
Mouse np95 sra domain non-specific DNA complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: np95. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chain:
B
(201 residues)
CATH domain:
|
|
|
|
|
|
Structure of uhrf1 in complex with histone tail
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D
(213 residues)
CATH domains:
|
|
|
|
|
|
Structure of uhrf1 in complex with histone tail
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(68 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the third pdz domain of human ligand-of-numb protein-x (lnx1) in complex with thE C-terminal peptide from the coxsackievirus and adenovirus receptor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lnx1, lnx. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(101 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the sra domain of e3 ubiquitin-protein ligase uhrf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(194 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of c-cbl-tkb domain complexed with its binding motif in sprouty2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: spry2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cbl, cbl2, rnf55.
|
|
|
Chain:
B
(304 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of c-cbl-tkb domain complexed with its binding motif in sprouty4
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
B
(304 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of c-cbl-tkb domain complexed with its binding motif in egf receptor'
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
B, D
(304 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of c-cbl-tkb domain complexed with its binding motif in syk
|
|
|
Source: Synthetic: yes. Other_details: synthetic construct. Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
B, D
(305 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of c-cbl-tkb domain complexed with its binding motif in c-met
|
|
|
Source: Synthetic: yes. Other_details: synthetic construct. Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
B, D
(305 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the bard1 ankyrin repeat domain and its functional consequences
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bard1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(125 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of thE C-terminal domain of the shigella type iii effector ipah
|
|
|
Source: Shigella flexneri 2a str. 301. Organism_taxid: 198214. Strain: 301 / serotype 2a. Gene: ipah1.4, cp0265. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(262 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of xiap bir3 domain in complex with a smac-mimetic compound, smac005
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4, api3, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
D, A, B, C
(101 residues)
CATH domain:
|
|
|
|
|
|
The set and ring associated (sra) domain of uhrf1 bound to methylated DNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic: yes
|
|
|
Chains:
A, B, C, D
(204 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap bir3 domain in complex with a smac-mimetic compound, smac010
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4, api3, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
D, A, B, C, E, F, G, H, I, J
(102 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir3 domain in complex with smac-mimetic compuond, smac005
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4, api3, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
C, A, B, D
(102 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the brct domains of human brca1 in complex with a phosphorylated peptide from human acetyl-coa carboxylase 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chains:
X, A, B, C, D, E, F, G
(208 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the full length ipah3
|
|
|
Source: Shigella flexneri 2a. Organism_taxid: 198214. Strain: 301. Gene: ipah_3. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(477 residues)
CATH domain:
|
|
|
|
|
|
Ciap1-bir3 in complex with n-terminal peptide from caspase-9 (atpfqe)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: peptide synthesized based on n-terminal fragment of caspase-9 (atpfqe).
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
The bir3 domain of ciap1 in complex with the n terminal peptide from smac/diablo (avpiaq).
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: peptide synthesized based on n-terminal fragment of smac/diablo (avpiaq).
|
|
|
Chain:
A
(92 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the tandem tudor domains of the e3 ubiquitin- protein ligase uhrf1 in complex with trimethylated histone h3-k9 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: trimethylated histone peptide h3-k9 was chemically synthesized. The sequence naturally occurs in homo sapiens (human)
|
|
|
Chain:
A
(140 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the tandem tudor domains of the e3 ubiquitin- protein ligase uhrf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(135 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the b2 box from murf1 in dimeric state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(48 residues)
CATH domain:
|
|
|
|
|
|
Structural insights into nedd8 activation of cullin-ring ligases: conformational control of conjugation.
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Gene: cul5, vacm1. Expressed in: escherichia coli. Gene: rbx1, rnf75, roc1.
|
|
|
Chain:
R
(87 residues)
CATH domain:
|
|
|
|
|
|
Structural insights into nedd8 activation of cullin-ring ligases: conformational control of conjugation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: nedd8. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cul5, vacm1. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 562
|
|
|
Chains:
R, Y
(86 residues)
CATH domain:
|
|
|
|
|
|
Structural and functional analysis of sra domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(193 residues)
CATH domain:
|
|
|
|
|
|
Structure of the ciap2 ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc3, api2, iap1, mihc, rnf49. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(65 residues)
CATH domain:
|
|
|
|
|
|
Structure of the ciap2 ring domain bound to ubch5b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc3, api2, iap1, mihc, rnf49. Expressed in: escherichia coli. Expression_system_taxid: 562. Xenopus laevis. Clawed frog, platanna. Organism_taxid: 8355.
|
|
|
Chain:
A
(64 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of pellino2 fha domain at 1.8 angstroms resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: peli2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(219 residues)
|
|
|
|
|
|
Structure of pellino2 fha domain at 3.3 angstroms resolution.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: peli2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(235 residues)
|
|
|
|
|
|
Crystal structure of human mdm2 in complex with a 12-mer peptide inhibitor
|
|
|
Source: Synthetic: yes. Other_details: this sequence occurs naturally in homo sapiens. Other_details: peptide identified by screening a duodecimal peptide library displayed on m13 phage
|
|
|
Chain:
A
(84 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap bir3 domain in complex with a smac-mimetic compound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc4, api3, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(101 residues)
CATH domain:
|
|
|
|
|
|
Structure of the bir domain from ml-iap bound to a peptidomimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: also known as kiap or mliap or livin, birc7, kiap, livin, mliap, rnf50, unq5800/pro19607/pro21344. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E
(99 residues)
CATH domain:
|
|
|
|
|
|
Structure of an ml-iap/xiap chimera bound to a peptidomimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7, kiap, livin, mliap, rnf50, unq5800/pro19607/pro21344. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
Structure of an ml-iap/xiap chimera bound to a peptidomimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7, kiap, livin, mliap, rnf50, unq5800/pro19607/pro21344. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
Mouse uhrf1 sra domain bound with hemi-methylated cpg, crystal structure in space group p21
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: uhrf1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic DNA oligo. Other_details: synthetic DNA oligo
|
|
|
Chains:
A, B
(206 residues)
CATH domain:
|
|
|
|
|
|
Mouse uhrf1 sra domain bound with hemi-methylated cpg, crystal structure in space group c222(1)
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: uhrf1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic DNA oligo. Other_details: synthetic DNA oligo
|
|
|
Chain:
B
(206 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the brca1 associated ring domain (bard1) tandem brct domains
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bard1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(203 residues)
CATH domains:
|
|
|
|
|
|
Mouse uhrf1 sra domain bound with hemi-methylated cpg DNA, crystal structure in space group c222(1) at 1.4 a resolution
|
|
|
Source: Mus musculus. Organism_taxid: 10090. Gene: np95, uhrf1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic DNA oligo. Other_details: synthetic DNA oligo
|
|
|
Chains:
A, B
(210 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ring domain of the e3 ubiquitin-protein ligase uhrf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: icbp90, np95, rnf106, uhrf1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(116 residues)
CATH domain:
|
|
|
|
|
|
Structure of human mdm2 in complex with high affinity peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic peptide
|
|
|
Chains:
A, C
(87 residues)
CATH domain:
|
|
|
|
|
|
The salmonella virulence effector ssph2 functions as a novel e3 ligase
|
|
|
Source: Salmonella typhimurium. Organism_taxid: 602. Strain: salmonella lt2. Gene: ssph2, stm2241. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(601 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir3 in complex with a bivalent compound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F, G, H
(97 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the rag1 nonamer-binding domain with DNA
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1, rag-1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic DNA. Other_details: synthetic DNA
|
|
|
Chain:
A
(68 residues)
CATH domain:
Unassigned
|
|
|
|
|
|
Crystal structure of the rag1 nonamer-binding domain with DNA
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1, rag-1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic: yes
|
|
|
Chain:
A
(68 residues)
CATH domain:
Unassigned
|
|
|
|
|
|
Ring1b c-terminal domain/cbx7 cbox complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bap1, ding, hipi3, ring1b, rnf2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cbx7.
|
|
|
Chains:
A, C
(109 residues)
CATH domain:
|
|
|
|
|
|
Structure of an ml-iap/xiap chimera bound to a peptidomimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
Structure of an ml-iap/xiap chimera bound to a peptidomimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
Structure of thE C-terminal domain of human rnf2/ring1b;
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bap1, ding, hipi3, ring1b, rnf2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(92 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the n-terminal domain of traf6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf85, traf6. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(157 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of traf6 in complex with ubc13 in the p1 space group
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf85, traf6. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: blu, ube2n.
|
|
|
Chain:
A
(104 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of traf6 in complex with ubc13 in the c2 space group
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf85, traf6. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: blu, ube2n.
|
|
|
Chains:
A, C
(106 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap bir3 with cs3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3, birc4, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(94 residues)
CATH domain:
|
|
|
|
|
|
Protease-associated domain of the e3 ligase grail
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: grail, rnf128. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chain:
A
(171 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human mdm2 in complex with a potent miniature protein inhibitor (18-residues)
|
|
|
Source: Synthetic: yes. Other_details: mdm2 sequence occurs naturally in humans. Other_details: desigend miniature protein
|
|
|
Chains:
A, C
(83 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human mdm2 complexed with d-peptide (12 residues)
|
|
|
Source: Synthetic: yes. Other_details: synthetic peptide, sequence found by phage display screening. Other_details: mdm2 sequence accurs naturally in humans
|
|
|
Chains:
A, C
(82 residues)
CATH domain:
|
|
|
|
|
|
Ring1b c-terminal domain/rybp c-terminal domain complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bap1, ding, hipi3, ring1b, rnf2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: dedaf, rybp, yeaf1.
|
|
|
Chains:
A, C, E, G, I, K
(111 residues)
CATH domain:
|
|
|
|
|
|
Cryo-em structure of the yeast spliceosome at 3.6 angstrom resolution
|
|
|
Source: Schizosaccharomyces pombe 972h-. Fission yeast. Organism_taxid: 284812. Strain: 972 / atcc 24843. Schizosaccharomyces pombe. Organism_taxid: 4896. Strain: 972 / atcc 24843
|
|
|
Chains:
S, T, U, V
(132 residues)
|
|
|
|
|
|
Cryo-electron microscopy structure of rag paired complex (with nbd, no symmetry)
|
|
|
Source: Danio rerio. Zebra fish. Organism_taxid: 7955. Strain: ab. Cell: b and t lymphocyte. Organelle: nucleus. Gene: rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chains:
A, C
(622 residues)
|
|
|
|
|
|
Cryo-electron microscopy structure of rag signal end complex (c2 symmetry)
|
|
|
Source: Danio rerio. Zebra fish. Organism_taxid: 7955. Strain: ab. Cell: b and t lymphocyte. Organelle: nucleus. Gene: rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chains:
A, C
(550 residues)
|
|
|
|
|
|
Cryo-electron microscopy structure of rag paired complex (c2 symmetry)
|
|
|
Source: Danio rerio. Zebra fish. Organism_taxid: 7955. Strain: ab. Cell: b and t lymphocyte. Organelle: nucleus. Gene: rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chains:
A, C
(550 residues)
|
|
|
|
|
|
Crystal structure of mdm2 with chromenotriazolopyrimidine 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(93 residues)
CATH domain:
|
|
|
|
|
|
Human mdm2 liganded with a 12mer peptide inhibitor (pdi6w)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chain:
A
(97 residues)
CATH domain:
|
|
|
|
|
|
Human mdm2 liganded with a 12mer peptide inhibitor (pdiq)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chain:
A
(83 residues)
CATH domain:
|
|
|
|
|
|
The crystal structure of brca1 brct in complex with a minimal recognition tetrapeptide with an amidated c-terminus
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans in the bach1/brip1 protein. The peptide is chemically synthesized.
|
|
|
Chain:
A
(211 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of brca1 brct in complex with a minimal recognition tetrapeptide with a free carboxy c-terminus.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans in the protein abraxas/ccdc98. The peptide is chemically synthesized.
|
|
|
Chain:
A
(211 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of brca1 brct d1840t in complex with a minimal recognition tetrapeptide with an amidated c-terminus
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: sequence occurs naturally in humans in the bach1/brip1 protein. Synthesized by the alberta peptide institute.
|
|
|
Chain:
A
(211 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of brca1 brct d1840t in complex with a minimal recognition tetrapeptide with a free carboxy c-terminus
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: sequence occurs naturally in humans in the abraxas/ccdc98 protein. Synthesized by the alberta peptide
|
|
|
Chain:
A
(211 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of fancl
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg12812. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
B, A
(364 residues)
CATH domains:
|
|
|
|
|
|
Pry-spry domain of human trim72
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pry-spry. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(193 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ring and first zinc finger domains of traf2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf2, trap3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(123 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ring domain of rnf168
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bc033791, rnf168. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(104 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of u-box domain of human e4b ubiquitin ligase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube4b, hdnb1, kiaa0684, ufd2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(75 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the u-box domain of human e4b ubiquitin ligase in complex with ubch5c e2 ubiquitin conjugating enzyme
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d3, ubch5c. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ube4b, hdnb1, kiaa0684, ufd2.
|
|
|
Chain:
B
(78 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of thE C-terminal domain of shigella type iii effector ipah9.8, with a novel domain swap
|
|
|
Source: Shigella flexneri. Organism_taxid: 623. Strain: ysh6000. Gene: ipah9.8. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(263 residues)
CATH domains:
|
|
|
|
|
|
Structure of human mdm2 protein in complex with a small molecule inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
Structure of human mdm2 protein in complex with mi-63-analog
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, C, E
(94 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human mdm2 in complex with d-peptide inhibitor (dpmi-alpha)
|
|
|
Source: Synthetic: yes. Other_details: mdm2 sequence occurs naturally in humans.. Other_details: synthetic peptide, d-enantiomer of phage-selected l- peptide
|
|
|
Chains:
A, C, E
(83 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human mdm2 with a 12-mer peptide inhibitor pmi (n8a mutant)
|
|
|
Source: Synthetic: yes. Other_details: this sequence occurs naturally in humans.. Other_details: synthetic peptide found by phage dissplay
|
|
|
Chains:
A, C, E, G, I, K, M, O
(85 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the u-box domain of human ubiquitin-protein ligase (e3), northeast structural genomics consortium target hr4604d.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa0898, mul, pob1, trim37. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(82 residues)
CATH domain:
|
|
|
|
|
|
The prp19 wd40 domain contains a conserved protein interaction region essential for its function.
|
|
|
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: prp19, pso4, yll036c. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(321 residues)
|
|
|
|
|
|
Crystal structure of traf2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F
(62 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of traf2:ciap2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: birc3, api2, iap1, mihc, rnf49.
|
|
|
Chains:
A, B, C, D
(62 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the traf1:traf2:ciap2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: traf1, ebi6. Expression_system_taxid: 562. Gene: birc3, api2, iap1, mihc, rnf49.
|
|
|
Chains:
A, B, D
(63 residues)
CATH domain:
|
|
|
|
|
|
Structure of bir1 from ciap1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(78 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ufd2 in complex with the ubiquitin-like (ubl) domain of rad23
|
|
|
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: d1255, ufd2, ydl190c. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rad23, sygp-orf29, yel037c.
|
|
|
Chain:
A
(955 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of ufd2 in complex with the ubiquitin-like (ubl) domain of dsk2
|
|
|
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: d1255, ufd2, ydl190c. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: dsk2, she4, ym8021.02, ymr276w.
|
|
|
Chain:
A
(953 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Ciap1-bir3 domain in complex with the smac-mimetic compound smac037
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api1, birc2, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(101 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the rnf4 ring domain dimer
|
|
|
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: rnf4. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(66 residues)
CATH domain:
|
|
|
|
|
|
The structure of ubr box (riaaa)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemical synthesis
|
|
|
Chain:
A
(79 residues)
CATH domain:
|
|
|
|
|
|
The structure of ubr box (kiaa)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemical synthesis
|
|
|
Chain:
A
(79 residues)
|
|
|
|
|
|
The structure of ubr box (hiaa)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemical synthesis
|
|
|
Chain:
A
(79 residues)
CATH domain:
|
|
|
|
|
|
The structure of ubr box (reaa)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemical synthesis
|
|
|
Chains:
A, B, D, F
(82 residues)
CATH domain:
|
|
|
|
|
|
The structure of ubr box (rdaa)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemical synthesis
|
|
|
Chains:
A, B, D, F
(81 residues)
CATH domain:
|
|
|
|
|
|
The structure of ubr box (rraa)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemical synthesis
|
|
|
Chains:
A, B, D, F
(82 residues)
CATH domain:
|
|
|
|
|
|
The structure of ubr box (rlges)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemical synthesis
|
|
|
Chains:
A, B
(80 residues)
CATH domain:
|
|
|
|
|
|
The structure of ubr box (native2)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, D, F
(82 residues)
CATH domain:
|
|
|
|
|
|
The structure of ubr box (native1)
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(89 residues)
|
|
|
|
|
|
Structure of the ubr-box of the ubr1 ubiquitin ligase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr1. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(73 residues)
|
|
|
|
|
|
Structure of the ubr-box of ubr2 ubiquitin ligase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr2, c6orf133, kiaa0349. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C, D, E, F, G, H
(72 residues)
|
|
|
|
|
|
Structure of the ubr-box of ubr2 in complex with n-degron
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr2, c6orf133, kiaa0349. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Other_details: chemically synthesized peptide
|
|
|
Chain:
A
(70 residues)
|
|
|
|
|
|
Crystal structure of trim24 phd-bromo in the free state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(172 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromo complexed with h3(13-32)k23ac peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in humans.
|
|
|
Chain:
A
(177 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromo complexed with h3(23-31)k27ac peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in humans
|
|
|
Chains:
A, B
(178 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromo complexed with h4(14-19)k16ac peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in humans
|
|
|
Chains:
A, B
(184 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromo complexed with h3(1-10)k4 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in humans
|
|
|
Chains:
A, B, C, D
(175 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of c-cbl tkb domain in complex with double phosphorylated spry2 peptide
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: synthetic peptide. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
B
(296 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of c-cbl tkb domain in complex with double phosphorylated egfr peptide
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: synthetic peptide. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
B
(296 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the sra domain of e3 ubiquitin-protein ligase uhrf2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: nirf, rnf107, rnf107., Uhrf2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(181 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of cbl-c (cbl-3) tkb domain in complex with egfr py1069 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl3, cblc, rnf57. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(321 residues)
CATH domains:
|
|
|
|
|
|
Ciap1-bir3 domain in complex with the smac-mimetic compound smac066
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(103 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of cbl-b tkb domain in complex with egfr py1069 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb, nbla00127, rnf56. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(302 residues)
CATH domains:
|
|
|
|
|
|
The carboxyl terminal domain of human deltex 3-like
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bbap, dtx3l. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(135 residues)
CATH domain:
|
|
|
|
|
|
Reverse binding mode of metrd peptide complexed with c-cbl tkb domain
|
|
|
Source: Synthetic: yes. Other_details: this is a designed peptide (two residues switched position) based on human met protein sequence.. Homo sapiens. Human. Organism_taxid: 9606. Gene: c-cbl. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
B, D
(301 residues)
CATH domains:
|
|
|
|
|
|
Impact of brca1 brct domain missense substitutions on phospho-peptide recognition: g1656d
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(207 residues)
CATH domains:
|
|
|
|
|
|
Impact of brca1 brct domain missense substitutions on phospho-peptide recognition: t1700a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(208 residues)
CATH domains:
|
|
|
|
|
|
Impact of brca1 brct domain missense substitutions on phospho-peptide recognition: r1699q
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
X
(206 residues)
CATH domains:
|
|
|
|
|
|
Impact of brca1 brct domain missense substitutions on phospho-peptide recognition: r1835p
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(209 residues)
CATH domains:
|
|
|
|
|
|
Impact of brca1 brct domain missense substitutions on phospho-peptide recognition: e1836k
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Other_details: peptide derived from brca1 partner bach1.
|
|
|
Chains:
A, B, C, D
(211 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of tpr domain of chip complexed with pseudophosphorylated smad1 peptide
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: stub1, chip. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Human.
|
|
|
Chain:
B
(132 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the tpr domain of chip complexed with hsp70-c peptide
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: stub1, chip. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Human.
|
|
|
Chain:
B
(132 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the tpr domain of chip complexed with phosphorylated smad1 peptide
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: stub1, chip. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Human.
|
|
|
Chain:
B
(132 residues)
CATH domain:
|
|
|
|
|
|
Bmi1/ring1b-ubch5c complex structure
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d3, ubc5c, ubch5c. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: bmi1, pcgf4, rnf51. Gene: rnf2, bap1, ding, hipi3, ring1b. Expression_system_taxid: 562
|
|
|
Chain:
C
(101 residues)
CATH domain:
|
|
|
|
|
|
A ring e3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-ring ligases
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 562
|
|
|
Chains:
B, D, F, H
(86 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of phd domain of uhrf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
|
|
|
Chain:
A
(67 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of drice and diap1-bir1 complex
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
E, F
(100 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of autoinhibited diap1-bir1 domain
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(103 residues)
CATH domain:
|
|
|
|
|
|
Structure of uhrf1 phd finger in complex with histone h3 1-9 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: icbp90, np95, rnf106, uhrf1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemically synthesized
|
|
|
Chains:
A, B
(68 residues)
CATH domain:
|
|
|
|
|
|
Structure of uhrf1 phd finger in complex with histone h3k4me3 1-9 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: icbp90, np95, rnf106, uhrf1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemically synthesized
|
|
|
Chains:
A, B
(67 residues)
CATH domain:
|
|
|
|
|
|
Structure of uhrf1 phd finger in the free form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: icbp90, np95, rnf106, uhrf1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(65 residues)
CATH domain:
|
|
|
|
|
|
Iap antagonist-induced conformational change in ciap1 promotes e3 ligase activation via dimerization
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api1, birc2, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(330 residues)
CATH domains:
|
|
|
|
|
|
Structure of uhrf1 in complex with unmodified h3 n-terminal tail
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(70 residues)
CATH domain:
|
|
|
|
|
|
Structure of a novel submicromolar mdm2 inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, C
(90 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human mdm2 in complex with a trifluoromethylated d-peptide inhibitor
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Synthetic: yes
|
|
|
Chains:
A, C, E
(84 residues)
CATH domain:
|
|
|
|
|
|
Exhaustive fluorine scanning towards potent p53-mdm2 antagonist
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(93 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of trim33 phd-bromo in the free state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim33, kiaa1113, rfg7, tif1g. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F, G, H, I, J, K, L
(178 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the complex of trim33 phd-bromo and h3(1-20) k9me3k14ac histone peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim33, kiaa1113, rfg7, tif1g. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in humans
|
|
|
Chains:
A, B
(185 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the complex of trim33 phd-bromo and h3(1-22) k9me3k14ack18ac histone peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim33, kiaa1113, rfg7, tif1g. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in humans
|
|
|
Chains:
A, B, C, D, E, F, G, H
(189 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the complex of trim33 phd-bromo and h3(1-28) k9me3k14ack18ack23ac histone peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim33, kiaa1113, rfg7, tif1g. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in humans
|
|
|
Chains:
A, B, C, D, E, F, G, H
(188 residues)
CATH domains:
|
|
|
|
|
|
Structure of the rhesus monkey trim5alpha deltav1 pryspry domain
|
|
|
Source: Macaca mulatta. Rhesus macaque,rhesus macaques,rhesus monkeys. Organism_taxid: 9544. Gene: trim5. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(183 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ciap1 bir3 bound to gdc0152
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api1, birc2, ciap1, iap2, mihb, rnf48, api3, birc4, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic inhibitor
|
|
|
Chain:
A
(87 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the bir domain of mliap bound to gdc0152
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc7, kiap, livin, mliap, rnf50, unq5800/pro19607/pro21344, api3, birc4, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic mimetic
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
Structure of the stapled p53 peptide bound to mdm2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic cyclic peptide
|
|
|
Chains:
A, B
(87 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human rnf146 wwe domain in complex with iso- adpribose
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf146. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(83 residues)
CATH domain:
|
|
|
|
|
|
Structure of hdm2 with dimer inducing indolyl hydantoin ro-2443
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Strain: human. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C, D
(84 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the n-terminal fragment of cbl-b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(287 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of a phosphotyrosine binding domain
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: cbll1, hakai. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(96 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure analysis of the pdz domain derived from the tight junction regulating protein
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: lnx1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure analysis of the pdz domain derived from the tight junction regulating protein
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: lnx1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in mus musculus
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the tyrosine kinase binding domain of cbl-c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblc. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(290 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the tyrosine kinase binding domain of cbl-c in complex with phospho-src peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblc. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans.
|
|
|
Chain:
A
(284 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PTR
is 76.19% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Crystal structure of the tyrosine kinase binding domain of cbl-c in complex with phospho-egfr peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblc. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans.
|
|
|
Chain:
A
(291 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PTR
is 76.19% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Crystal structure of the tyrosine kinase binding domain of cbl-c (pl mutant)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblc. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(278 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the tyrosine kinase binding domain of cbl-c (pl mutant) in complex with phospho-egfr peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblc. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans.
|
|
|
Chain:
A
(291 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PTR
is 76.19% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(85 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(85 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the roq domain of human roquin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rc3h1, kiaa2025, rnf198. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(149 residues)
CATH domain:
|
|
|
|
|
|
The structure of the traf domain of human traf4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C
(172 residues)
CATH domain:
|
|
|
|
|
|
Structure of phosphotyr363-cbl-b - ubch5b-ub - zap-70 peptide complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Expression_system_taxid: 562
|
|
|
Chains:
A, E, I, M
(390 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PRO
is 50.00% similar to
enzyme reactant protein
|
|
|
|
|
|
|
Mouse igg2a in complex with mouse trim21 pryspry
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(180 residues)
CATH domain:
|
|
|
|
|
|
Human fancl central domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(186 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PRO
is 46.67% similar to
enzyme reactant protein
|
|
|
|
|
|
|
Solution structure of the ring finger-like domain of retinoblastoma binding protein-6 (rbbp6)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(92 residues)
CATH domain:
|
|
|
|
|
|
Phd finger of human uhrf1 in complex with unmodified histone h3 n- terminal tail
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta 2. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(65 residues)
CATH domain:
|
|
|
|
|
|
Phd finger of human uhrf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta 2.
|
|
|
Chain:
B
(55 residues)
CATH domain:
|
|
|
|
|
|
Structure of the cand1-cul4b-rbx1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five. Mus musculus. House mouse. Organism_taxid: 10090.
|
|
|
Chains:
D, F
(89 residues)
CATH domain:
|
|
|
|
|
|
Structure of ddb1-ddb2-cul4a-rbx1 bound to a 12 bp abasic site containing DNA-duplex
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five. Mus musculus. House mouse. Organism_taxid: 10090. Danio rerio.
|
|
|
Chain:
B
(21 residues)
|
|
|
|
|
|
Structure of ddb1-ddb2-cul4b-rbx1 bound to a 12 bp abasic site containing DNA-duplex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five. Danio rerio. Zebrafish. Organism_taxid: 7955.
|
|
|
Chains:
F, I
(21 residues)
|
|
|
|
|
|
Structure of phosphotyr371-c-cbl-ubch5b complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expression_system_taxid: 469008
|
|
|
Chain:
A
(77 residues)
CATH domain:
|
|
|
|
|
|
Structure of modified phosphotyr371-c-cbl-ubch5b-zap-70 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold. Synthetic: yes.
|
|
|
Chain:
A
(388 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PRO
is 50.00% similar to
enzyme reactant protein
|
|
|
|
|
|
|
Structure of phosphotyr371-c-cbl-ubch5b-zap-70 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold. Synthetic: yes.
|
|
|
Chain:
A
(388 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PRO
is 50.00% similar to
enzyme reactant protein
|
|
|
|
|
|
|
Rnf4 - ubch5a - ubiquitin heterotrimeric complex
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expression_system_taxid: 562
|
|
|
Chain:
A
(129 residues)
CATH domain:
|
|
|
|
|
|
Structure of birc7-ubch5b-ub complex.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
B, E
(57 residues)
CATH domain:
|
|
|
|
|
|
Rnf8 ring domain structure
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss.
|
|
|
Chains:
A, B
(136 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of rhesus trim5alpha pry/spry domain
|
|
|
Source: Escherichia coli, macaca mulatta. Organism_taxid: 511693, 9544. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(557 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of the msl1-msl2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star.
|
|
|
Chains:
C, D
(115 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the msl1-msl2 complex (3.5a)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star.
|
|
|
Chains:
C, D, G, H, K, L
(115 residues)
CATH domain:
|
|
|
|
|
|
Pry-spry domain of trim25
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(194 residues)
CATH domain:
|
|
|
|
|
|
Zebrafish znrf3 ectodomain crystal form i
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, B
(143 residues)
CATH domain:
|
|
|
|
|
|
Zebrafish znrf3 ectodomain crystal form ii
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, B
(143 residues)
CATH domain:
|
|
|
|
|
|
Mouse znrf3 ectodomain crystal form i
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, B
(152 residues)
CATH domain:
|
|
|
|
|
|
Mouse znrf3 ectodomain crystal form ii
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, B, C
(146 residues)
CATH domain:
|
|
|
|
|
|
Mouse znrf3 ectodomain crystal form iii
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, B
(146 residues)
CATH domain:
|
|
|
|
|
|
Mouse znrf3 ectodomain crystal form iv
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, B, C, D
(137 residues)
CATH domain:
|
|
|
|
|
|
Mouse znrf3 ectodomain crystal form v, disulfide-bridged s90c variant
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(144 residues)
CATH domain:
|
|
|
|
|
|
Xenopus znrf3 ectodomain crystal form i
|
|
|
Source: Xenopus (silurana) tropicalis. Western clawed frog. Organism_taxid: 8364. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, B
(146 residues)
CATH domain:
|
|
|
|
|
|
Xenopus znrf3 ectodomain crystal form ii
|
|
|
Source: Xenopus (silurana) tropicalis. Western clawed frog. Organism_taxid: 8364. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, B
(146 residues)
CATH domain:
|
|
|
|
|
|
Mouse znrf3 ectodomain in complex with mouse rspo2 fu1-fu2 crystal form i
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, C
(153 residues)
CATH domain:
|
|
|
|
|
|
Mouse znrf3 ectodomain in complex with xenopus rspo2 fu1-fu2 (seleno met) crystal form i
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t. Xenopus (silurana) tropicalis. Western clawed frog. Organism_taxid: 8364.
|
|
|
Chains:
A, C
(153 residues)
CATH domain:
|
|
|
|
|
|
Mouse znrf3 ectodomain in complex with xenopus rspo2 fu1-fu2 (seleno met) crystal form ii
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t. Xenopus (silurana) tropicalis. Western clawed frog. Organism_taxid: 8364.
|
|
|
Chains:
A, C, E, G
(153 residues)
CATH domain:
|
|
|
|
|
|
Xenopus znrf3 ectodomain in complex with xenopus rspo2 fu1-fu2 crystal form i
|
|
|
Source: Xenopus (silurana) tropicalis. Western clawed frog. Organism_taxid: 8364. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, C
(161 residues)
CATH domain:
|
|
|
|
|
|
Xenopus znrf3 ectodomain in complex with xenopus rspo2 fu1-fu2 crystal form ii
|
|
|
Source: Xenopus (silurana) tropicalis. Western clawed frog. Organism_taxid: 8364. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, C
(161 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of siah1 at 1.95 a resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold.
|
|
|
Chains:
A, B
(193 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of siah1 at 1.58 a resolution.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold.
|
|
|
Chains:
A, B
(189 residues)
CATH domains:
|
|
|
|
|
|
Structure of an e2-e3 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
X, Y
(75 residues)
CATH domain:
|
|
|
|
|
|
Structure of znrf3 ectodomain
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293
|
|
|
Chains:
A, B
(153 residues)
CATH domain:
|
|
|
|
|
|
Structure of znrf3-rspo1
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Homo sapiens. Hhuma. Organism_taxid: 9606.
|
|
|
Chains:
A, B, C, D
(152 residues)
CATH domain:
|
|
|
|
|
|
Structure of the trim25 coiled-coil
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(164 residues)
|
|
|
|
|
|
The central valine concept provides an entry in a new class of non peptide inhibitors of the p53-mdm2 interaction
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(93 residues)
CATH domain:
|
|
|
|
|
|
Ciap1-bir3 in complex with a divalent smac mimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(102 residues)
CATH domain:
|
|
|
|
|
|
Xiap-bir3 in complex with a potent divalent smac mimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, J, F, G, K, L
(109 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of mdm2 (17-111) in complex with compound 23
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(85 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of mdm2 (17-111) in complex with compound 29 (am- 8553)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E
(92 residues)
CATH domain:
|
|
|
|
|
|
Structure of a glomulin-rbx1-cul1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 562. Gene: glmn, fap48, fap68, vmglom.
|
|
|
Chains:
B, D
(84 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ring domain of rnf168
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(91 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of traf3/cardif
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: traf3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: chemical synthesis
|
|
|
Chain:
A
(190 residues)
CATH domain:
|
|
|
|
|
|
Structure of cbl(tkb) bound to a phosphorylated pentapeptide
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
B
(305 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the tandem tudor domain and plant homeodomain of uhrf1 with histone h3k9me3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans
|
|
|
Chains:
A, B, C, D
(215 residues)
CATH domains:
|
|
|
|
|
|
Ordering of the n terminus of human mdm2 by small molecule inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F, G, H
(106 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of an mdm2/p53 peptide complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: synthetic construct
|
|
|
Chains:
A, C
(83 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of an mdm2/nutlin-3a complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(91 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap bir3 with t3256336
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3, birc4, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F, G, H
(96 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ciap1 bir3 bound to t3170284
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api1, birc2, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(92 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ciap1 bir3 bound to t3256336
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api1, birc2, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(95 residues)
CATH domain:
|
|
|
|
|
|
Siah1 bound to synthetic peptide (ace)klrpv(aba)mvrptvr
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: siah1, humsiah. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Drosophila melanogaster. Fruit fly.
|
|
|
Chains:
A, C
(189 residues)
CATH domains:
|
|
|
|
|
|
Siah1 mutant bound to synthetic peptide (ace)klrpv(23p)mvrpwvr
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: siah1, humsiah. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Drosophila melanogaster. Fruit fly.
|
|
|
Chains:
A, C
(188 residues)
CATH domains:
|
|
|
|
|
|
Siah1 bound to synthetic peptide (ace)klrpvamvrp(prk)vr
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: humsiah, siah1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Drosophila melanogaster. Fruit fly.
|
|
|
Chains:
A, C
(187 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the xiap ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3, bir4, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(62 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the f495l mutant xiap ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3, bir4, iap3, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(63 residues)
CATH domain:
|
|
|
|
|
|
Structure of human brca1 brct in complex with baat peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Other_details: the sequence occurs naturally in humans
|
|
|
Chain:
A
(211 residues)
CATH domains:
|
|
|
|
|
|
Structure of human brca1 brct in complex with atrip peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Other_details: this sequence occurs naturally in humans.
|
|
|
Chains:
A, B
(211 residues)
CATH domains:
|
|
|
|
|
|
The 1.7a crystal structure of humanized xenopus mdm2 with ro5045337
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
The 1.9a crystal structure of humanized xenopus mdm2 with nutlin-3a
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(86 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3, birc4, iap3, u32974, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, C
(83 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 domain with aiav bound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3, birc4, iap3, u32974, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, C
(83 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 domain with ataa bound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3, birc4, iap3, u32974, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthesized
|
|
|
Chains:
A, C
(83 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 domain with avpi bound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3, birc4, iap3, u32974, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthesized
|
|
|
Chains:
A, C
(83 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 domain with svpi bound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3, birc4, iap3, u32974, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthesized
|
|
|
Chains:
A, C
(83 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 domain with amrv bound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3, birc4, iap3, u32974, xiap. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, C
(84 residues)
CATH domain:
|
|
|
|
|
|
The 1.2a crystal structure of humanized xenopus mdm2 with ro0503918 - a nutlin fragment
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(86 residues)
CATH domain:
|
|
|
|
|
|
The 1.25a crystal structure of humanized xenopus mdm2 with a nutlin fragment, ro5045331
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(86 residues)
CATH domain:
|
|
|
|
|
|
The 1.63a crystal structure of humanized xenopus mdm2 with a nutlin fragment, ro5524529
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(86 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of brca1 brct with doubly phosphorylated abraxas
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
|
|
|
Chain:
A
(211 residues)
CATH domains:
|
|
|
|
|
|
The 1.9a crystal structure of humanized xenopus mdm2 with ro5313109 - a pyrrolidine mdm2 inhibitor
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(84 residues)
CATH domain:
|
|
|
|
|
|
The 2.5a crystal structure of humanized xenopus mdm2 with ro5316533 - a pyrrolidine mdm2 inhibitor
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(83 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhibitor (2s,5r,6s)-2-benzyl-5,6- bis(4-bromophenyl)-4-methylmorpholin-3-one
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhibitor (2s,5r,6s)-2-benzyl-5,6- bis(4-chlorophenyl)-4-methylmorpholin-3-one
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhibitor (2r,3e)-2-[(2s,3r,6s)-2,3- bis(4-chlorophenyl)-6-(4-fluorobenzyl)-5-oxomorpholin-4-yl]pent-3- enoic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(92 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhibitor (2's,3r,4's,5'r)-n-(2- aminoethyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2- dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'- carboxamide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E
(89 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhibitor {(2s,5r,6s)-6-(3- chlorophenyl)-5-(4-chlorophenyl)-4-[(2s)-1-hydroxybutan-2-yl]-3- oxomorpholin-2-yl}acetic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(88 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of traf4 traf domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf4. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(178 residues)
CATH domain:
|
|
|
|
|
|
Structure of the chip-tpr domain in complex with the hsc70 lid-tail domains
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chip, pp1131, stub1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: hsc70, hsp73, hspa10, hspa8.
|
|
|
Chains:
A, B
(130 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 with a bound benzodiazepinone inhibitor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, C
(82 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 with a bound spirocyclic benzoxazepinone inhibitor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, C
(83 residues)
CATH domain:
|
|
|
|
|
|
Structure of ciap1-bir3 and inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(103 residues)
CATH domain:
|
|
|
|
|
|
Structure of xiap-bir3 and inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(98 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human lgr5-rspo1-rnf43
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lgr5, gpr49, gpr67. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Gene: rspo1. Gene: rnf43.
|
|
|
Chains:
E, F
(149 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of prpf19 wd40 repeats
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: sf9. Gene: prpf19, nmp200, prp19, snev. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
|
|
|
Chain:
A
(310 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of clap1 bir3 bound to t3261256
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api1, birc2, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(92 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of clap1 bir3 bound to t3226692
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api1, birc2, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
Coiled-coil domain of trim25
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(171 residues)
|
|
|
|
|
|
The 1.6a crystal structure of humanized xenopus mdm2 with ro5027344
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(86 residues)
CATH domain:
|
|
|
|
|
|
The 1.14a crystal structure of humanized xenopus mdm2 with ro5499252
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(85 residues)
CATH domain:
|
|
|
|
|
|
The 2.3a crystal structure of humanized xenopus mdm2 with ro5545353
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C
(85 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the coiled coil domain of murf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: irf, murf1, rnf28, smrz, trim63. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, C, B, D
(60 residues)
CATH domain:
|
|
|
|
|
|
Traf domain of human traf4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf4, cart1, mln62, rnf83. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(159 residues)
CATH domain:
|
|
|
|
|
|
Structure of a novel submicromolar mdm2 inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(94 residues)
CATH domain:
|
|
|
|
|
|
Structure of a novel submicromolar mdm2 inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(86 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ciap1 bir3 bound to t3258042
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api1, birc2, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(94 residues)
CATH domain:
|
|
|
|
|
|
Structure of xiap-bir1 in complex with nf023
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(78 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ciap1 bir3 bound to t3450325
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api1, birc2, iap2, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(90 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ssph1 lrr domain in complex pkn1 hr1b domain
|
|
|
Source: Salmonella enterica subsp. Enterica serovar typhimurium. Organism_taxid: 588858. Strain: 14028s. Gene: ssph1, stm14_1483. Expressed in: escherichia coli. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, C
(233 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ssph1 lrr domain
|
|
|
Source: Salmonella enterica subsp. Enterica serovar typhimurium. Organism_taxid: 588858. Strain: 14028s. Gene: ssph1, stm14_1483. Expressed in: escherichia coli.
|
|
|
Chains:
A, B, C, D, E, F
(236 residues)
CATH domain:
|
|
|
|
|
|
Structure of coiled-coil domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim69. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(177 residues)
|
|
|
|
|
|
Co-crystal structure of mdm2 (17-111) in complex with compound 25
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E
(93 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhibitor compound 4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(88 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2(17-111) in complex with compound 48
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E
(93 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhibitor compound 4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(105 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhibitor compound 47
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(99 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human brca1 brct in complex with nonphosphopeptide inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes
|
|
|
Chain:
A
(209 residues)
CATH domains:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhbitor compound 3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(100 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhbitor compound 46
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(99 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of mdm2 with inhibitor compound 49
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(89 residues)
CATH domain:
|
|
|
|
|
|
Tetra-substituted imidazoles as a new class of inhibitors of the p53- mdm2 interaction
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(93 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of rnf8 bound to the ubc13/mms2 heterodimer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mms2, ube2v2, uev2. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: ube2n, blu. Gene: rnf8, kiaa0646.
|
|
|
Chains:
C, G, H, K, L
(92 residues)
|
|
|
|
|
|
Crystal structure of xiap bir1 domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: api3,birc4,iap3,xiap. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(78 residues)
CATH domain:
|
|
|
|
|
|
Structure of an rbx1-ubc12~nedd8-cul1-dcn1 complex: a ring-e3- e2~ubiquitin-like protein-substrate intermediate trapped in action
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rbx1, rnf75, roc1. Gene: dcun1d1, dcun1l1, rp42, sccro. Gene: ube2m, ubc12.
|
|
|
Chains:
B, D
(75 residues)
CATH domain:
|
|
|
|
|
|
Human rnf4 ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: res4-26, rnf4, snurf. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(66 residues)
CATH domain:
|
|
|
|
|
|
Complex between the salmonella t3ss effector slrp and its human target thioredoxin-1
|
|
|
Source: Salmonella enterica subsp. Enterica serovar typhimurium. Organism_taxid: 588858. Strain: 14028. Gene: slrp, stm14_928. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
|
|
|
Chains:
A, B
(599 residues)
|
|
|
|
|
|
Structure of uhrf2-sra in complex with a 5hmc-containing DNA, complex i
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf2, nirf, rnf107. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic: yes
|
|
|
Chains:
A, B, E, F
(189 residues)
CATH domain:
|
|
|
|
|
|
Structure of uhrf2-sra in complex with a 5hmc-containing DNA, complex ii
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf2, nirf, rnf107. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic: yes
|
|
|
Chains:
A, B
(188 residues)
CATH domain:
|
|
|
|
|
|
Structure of uhrf2-sra in complex with a 5mc-containing DNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf2, nirf, rnf107. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic: yes
|
|
|
Chains:
A, B, E, F
(197 residues)
CATH domain:
|
|
|
|
|
|
X-ray structure of the roq domain from murine roquin-1
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: gm551, kiaa2025, rc3h1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(153 residues)
CATH domain:
|
|
|
|
|
|
X-ray structure of the roq domain from murine roquin-1 in complex with a 23-mer tnf-cde RNA
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: gm551, kiaa2025, rc3h1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: RNA oligomer was chemically synthesized
|
|
|
Chains:
A, B, C, D
(153 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the roq domain of human roquin in complex with the tnf23 RNA duplex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rc3h1, kiaa2025, rnf198. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chains:
A, B
(302 residues)
|
|
|
|
|
|
Crystal structure of the roq domain of human roquin in complex with the hmg19 stem-loop RNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rc3h1, kiaa2025, rnf198. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes
|
|
|
Chains:
A, B
(299 residues)
|
|
|
|
|
|
Crystal structure of a functionally uncharacterized domain of e3 ubiquitin ligase shprh
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: shprh, kiaa2023. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(372 residues)
|
|
|
|
|
|
Co-crystal structure of mdm2 (17-111) with compound 16, {(3r,5r,6s)-5- (3-chlorophenyl)-6-(4-chlorophenyl)-1-[(1s)-1-(6-cyclopropylpyridin- 2-yl)propyl]-3-methyl-2-oxopiperidin-3-yl}acetic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(89 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of compound 16 bound to mdm2(17-111), {(3r,5r,6s)-5- (3-chlorophenyl)-6-(4-chlorophenyl)-1-[(1s)-1-cyclopropyl-2- (pyrrolidin-1-ylsulfonyl)ethyl]-3-methyl-2-oxopiperidin-3-yl}acetic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, C, E, G, I, K
(92 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of rnf146(ring-wwe)/ubch5a/iso-adpr complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rnf146. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, C
(153 residues)
|
|
|
|
Bound ligand:
|
Het Group V3L
is 63.89% similar to
enzyme product AMP
|
|
|
|
|
|
|
Crystal structure of tandem tudor domains of uhrf1 in complex with a small organic molecule
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(134 residues)
CATH domains:
|
|
|
|
|
|
Structure of bre1 ring domain
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: bre1, ydl074c. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(69 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ring1b/bmi1/ubch5c prc1 ubiquitylation module bound to the nucleosome core particle
|
|
|
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: histone h3.2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: histone h4. Gene: hist1h2aj, loc494591. Gene: histone h2b 1.1.
|
|
|
Chains:
L, N
(254 residues)
|
|
|
|
|
|
Structure of the msl2 cxc domain bound with a non-specific (gc)6 DNA
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg3241, msl-2, msl2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chains:
A, B
(37 residues)
|
|
|
|
|
|
Structure of the msl2 cxc domain bound with a specific mre sequence
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg3241, msl-2, msl2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic: yes
|
|
|
Chains:
C, D, E, F
(47 residues)
|
|
|
|
|
|
Crystal structure of hltf hiran domain bound to DNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hltf, hip116a, rnf80, smarca3, snf2l3, zbu1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B, C, D
(122 residues)
|
|
|
|
|
|
Pcgf5-ring1b-ubch5c complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d3, ubc5c, ubch5c. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf2, bap1, ding, hipi3, ring1b. Gene: pcgf5, rnf159. Expression_system_taxid: 562
|
|
|
Chains:
B, E
(105 residues)
CATH domain:
|
|
|
|
|
|
Complex of ubc13 with the ring domain of the trim5alpha retroviral restriction factor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2n, blu. Expressed in: escherichia coli. Expression_system_taxid: 511693. Macaca mulatta. Rhesus macaque. Organism_taxid: 9544.
|
|
|
Chain:
B
(63 residues)
CATH domain:
|
|
|
|
|
|
Structure of the bbox-coiled-coil region of rhesus trim5alpha
|
|
|
Source: Macaca mulatta, enterobacteria phage t4. Rhesus macaque. Organism_taxid: 9544, 10665. Gene: trimcyp. Expressed in: escherichia coli. Expression_system_taxid: 469008, 562.
|
|
|
Chains:
A, B
(359 residues)
|
|
|
|
|
|
Crystal structure of the mib repeat domain of mind bomb 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mib1, dip1, kiaa1323, zzank2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(157 residues)
|
|
|
|
|
|
Tandem tudor and phd domains of uhrf2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf2, nirf, rnf107. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(222 residues)
CATH domains:
Unassigned
|
|
|
|
|
|
Crystal structure of n-terminus of roquin
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rc3h1, gm551, kiaa2025. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(367 residues)
|
|
|
|
|
|
Complex structure of brca1 brct with singly phospho abraxas
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C
(214 residues)
CATH domains:
|
|
|
|
|
|
Structure of the stapled peptide ys-02 bound to mdm2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B, C, D
(97 residues)
CATH domain:
|
|
|
|
|
|
Structure of the stapled peptide ys-01 bound to mdm2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D
(100 residues)
CATH domain:
|
|
|
|
|
|
Low resolution structure r-spondin-2 (fu1fu2) in complex with the ectodomains of lgr5 and znrf3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
C
(153 residues)
|
|
|
|
|
|
Crystal structure of the roq-domain of human roquin1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(150 residues)
CATH domain:
|
|
|
|
|
|
Structure of a stapled peptide antagonist bound to nutlin-resistant mdm2.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(95 residues)
CATH domain:
|
|
|
|
|
|
Rnf38-ubch5b-ub complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
C, F
(75 residues)
CATH domain:
|
|
|
|
|
|
Rnf38-ub-ubch5b-ub complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
C
(69 residues)
CATH domain:
|
|
|
|
|
|
E3 ubiquitin-protein ligase rnf8 in complex with ubiquitin-conjugating enzyme e2 n and polyubiquitin-b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2n, blu. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: rnf8, kiaa0646. Gene: ubb. Expression_system_taxid: 562.
|
|
|
Chains:
C, D, I, J
(136 residues)
|
|
|
|
|
|
Co-crystal structure of mdm2 in complex with am-7209
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(105 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 domain complexed with (s)-3-(4- methoxyphenyl)-2-((s)-2-((s)-1-((s)-2-((s)-2-(methylamino) propanamido)pent-4-ynoyl)pyrrolidine-2-carboxamido)-3- phenylpropanamido)propanoic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes
|
|
|
Chain:
A
(79 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 domain complexed with ligand bound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes
|
|
|
Chains:
A, B
(79 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of xiap-bir2 domain complexed with ligand bound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
|
|
|
Chain:
A
(79 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the core rag1/2 recombinase
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek 293t. Gene: rag2, rag-2. Expression_system_cell_line: hek 293t
|
|
|
Chains:
B, E
(612 residues)
|
|
|
|
|
|
Crystal structure of u-box 1 of lubx / legu2 / lpp2887 from legionella pneumophila str. Paris
|
|
|
Source: Legionella pneumophila (strain paris). Organism_taxid: 297246. Strain: paris. Gene: lubx, lpp2887. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: ril.
|
|
|
Chain:
A
(109 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of u-box 2 of lubx / legu2 / lpp2887 from legionella pneumophila str. Paris, ile175met mutant
|
|
|
Source: Legionella pneumophila. Organism_taxid: 297246. Strain: paris. Gene: lubx, lpp2887. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C
(75 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex between lubx/legu2/lpp2887 u-box 1 and homo sapiens ube2d2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Legionella pneumophila. Organism_taxid: 297246. Strain: paris.
|
|
|
Chain:
B
(183 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of siah1 sina domain in complex with a usp19 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: siah1, humsiah. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: v2r-prare2. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(188 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of u-box 2 of lubx / legu2 / lpp2887 from legionella pneumophila str. Paris, wild-type
|
|
|
Source: Legionella pneumophila (strain paris). Organism_taxid: 297246. Strain: paris. Gene: lubx, lpp2887. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C
(76 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the mzm-rep domains of mind bomb 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mib1, dip1, kiaa1323, zzank2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(363 residues)
|
|
|
|
|
|
Crystal structure of the mzm-rep domains of mind bomb 1 in complex with jagged1 n-box peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mib1, dip1, kiaa1323, zzank2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(362 residues)
|
|
|
|
|
|
Crystal structure of the mzm-rep domains of mind bomb 1 in complex with fly delta n-box peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mib1, dip1, kiaa1323, zzank2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Drosophila melanogaster. Organism_taxid: 7227
|
|
|
Chain:
A
(362 residues)
|
|
|
|
|
|
Crystal structure of human mdm2-rpl11
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rpl11. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: mdm2. Expression_system_taxid: 562
|
|
|
Chain:
B
(42 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of hiran domain of human hltf in complex with DNA
|
|
|
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human. Organism_taxid: 9606. Gene: hltf, hip116a, rnf80, smarca3, snf2l3, zbu1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(121 residues)
|
|
|
|
|
|
Crystal structure of hiran domain of human hltf
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hltf, hip116a, rnf80, smarca3, snf2l3, zbu1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F, G, H, I
(121 residues)
|
|
|
|
|
|
Structure of brca1 brct domains in complex with abraxas double phosphorylated peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D, E, F, G, H
(214 residues)
CATH domains:
|
|
|
|
|
|
Structure of brca1 brct domains in complex with abraxas single phosphorylated peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(214 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromodomain complexed with 1-methyl-5- (2-methyl-1 3-thiazol-4-yl)-2 3-dihydro-1h-indol-2-one (1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(178 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromodomain complexed with 2,4- dimethoxy-n-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)benzene- 1-sulfonamide (3b)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(178 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromodomain complexed with n-(1,3- dimethyl-2-oxo-2,3-dihydro-1h-1,3-benzodiazol-5-yl)-4-methoxybenzene- 1-sulfonamide (5b)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(173 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromodomain complexed with n-[6-(4- methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1h-1,3-benzodiazol-5- yl]benzenesulfonamide (5g)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(180 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromodomain complexed with n-{6-[3- (benzyloxy)phenoxy]-1,3-dimethyl-2-oxo-2,3-dihydro-1h-1,3- benzodiazol-5-yl}-3,4-dimethoxybenzene-1-sulfonamide (7b)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(177 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromodomain complexed with n-{1,3- dimethyl-6-[3-(2-methylpropoxy)phenoxy]-2-oxo-2,3-dihydro-1h-1,3- benzodiazol-5-yl}-1,2-dimethyl-1h-imidazole-4-sulfonamide (7g)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(178 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromodomain complexed with n-{1,3- dimethyl-2-oxo-6-[3-(oxolan-3-ylmethoxy)phenoxy]-2,3-dihydro-1h-1,3- benzodiazol-5-yl}-1-methyl-1h-imidazole-4-sulfonamide (7l)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(178 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of trim24 phd-bromodomain complexed with n-(6-{3-[4- (dimethylamino)butoxy]-5-propoxyphenoxy}-1,3-dimethyl-2-oxo-2,3- dihydro-1h-1,3-benzodiazol-5-yl)-3,4-dimethoxybenzene-1-sulfonamide (8i)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(180 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the roq domain of human roquin-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rc3h1, kiaa2025, rnf198. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(152 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the roq domain of human roquin-2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rc3h2, mnab, rnf164. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(294 residues)
|
|
|
|
|
|
Crystal structure of the rc3h2 roq domain in complex with stem-loop and double-stranded forms of RNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rc3h2, mnab, rnf164. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(293 residues)
|
|
|
|
|
|
Crystal structure of the mavs-traf6 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf6, rnf85. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: condonplus.
|
|
|
Chains:
A, B
(152 residues)
CATH domain:
|
|
|
|
|
|
Spliceosome component
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: s288c. Gene: prp19, pso4, yll036c. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(354 residues)
|
|
|
|
|
|
Structure of mdm2 with low molecular weight inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(95 residues)
CATH domain:
|
|
|
|
|
|
Structure of mdm2 with low molecular weight inhibitor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(94 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the roq domain of human roquin-2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rc3h2, mnab, rnf164. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(155 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human roquin-2 roq domain in complex with roquin cde RNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rc3h2, mnab, rnf164. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(151 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of trim24 with 3,4-dimethoxy-n-(6-(4- methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-5- yl)benzenesulfonamide inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(177 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of human pcna in complex with a traip peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pcna. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
D, E
(12 residues)
|
|
|
|
|
|
Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-mdm2 interaction with a distinct binding mode: hdm2 (mdm2) complexed with cpd5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(84 residues)
CATH domain:
|
|
|
|
|
|
Discovery of nvp-cgm097 - a highly potent and selective mdm2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: hdm2 (mdm2) complexed with nvp-cgm097
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(93 residues)
CATH domain:
|
|
|
|
|
|
Discovery of nvp-cgm097 - a highly potent and selective mdm2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: hdm2 (mdm2) complexed with cpd2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(90 residues)
CATH domain:
|
|
|
|
|
|
Structure of the stapled peptide bound to mdm2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Syhthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(83 residues)
CATH domain:
|
|
|
|
|
|
Not4 ring domain in complex with ubc4
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: s288c. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss.
|
|
|
Chain:
A
(54 residues)
|
|
|
|
|
|
A complex of of rnf4-ring domain, ubev2, ubc13-ub (isopeptide crosslink)
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Bos taurus.
|
|
|
Chain:
A
(129 residues)
CATH domain:
|
|
|
|
|
|
A complex of rnf4-ring domain, ubc13-ub (isopeptide crosslink)
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expression_system_taxid: 562
|
|
|
Chain:
A
(123 residues)
CATH domain:
|
|
|
|
|
|
Not1 c-terminal domain in complex with not4
|
|
|
Source: Saccharomyces cerevisiae. Organism_taxid: 889517. Strain: cen.Pk113-7d. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss. Organism_taxid: 559292. Strain: s288c.
|
|
|
Chains:
B, D, F, H, J, L
(50 residues)
|
|
|
|
|
|
Crystal structure of cbl-b tkb domain in complex with cblin
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: cblb. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: irs-1
|
|
|
Chains:
A, B, C
(305 residues)
CATH domains:
|
|
|
|
|
|
Structure of shigella effector lrr domain
|
|
|
Source: Shigella flexneri. Organism_taxid: 623. Gene: ipah9.8, cp0226, pwr501_0234, sflp090. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(218 residues)
CATH domain:
|
|
|
|
|
|
Structure of shigella effector lrr domain
|
|
|
Source: Shigella flexneri. Organism_taxid: 623. Gene: ipah9.8, cp0226, pwr501_0234, sflp090. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(220 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the hltf hiran domain with a ssdna fragment
|
|
|
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human. Organism_taxid: 9606. Gene: hltf. Expressed in: enterobacteria phage l1. Expression_system_taxid: 268588
|
|
|
Chains:
A, D
(123 residues)
|
|
|
|
|
|
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(104 residues)
CATH domain:
|
|
|
|
|
|
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(106 residues)
CATH domain:
|
|
|
|
|
|
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(106 residues)
CATH domain:
|
|
|
|
|
|
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(106 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of usp7/hausp in complex with icp0
|
|
|
Source: Synthetic: yes. Human herpesvirus 1. Hhv-1. Organism_taxid: 10298. Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli.
|
|
|
Chain:
B
(13 residues)
|
|
|
|
|
|
Crystal structure of hdm2 in complex with nutlin-3a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(92 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of usp7 in complex with uhrf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: uhrf1, icbp90, np95, rnf106. Expression_system_taxid: 562
|
|
|
Chain:
C
(13 residues)
|
|
|
|
|
|
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(106 residues)
CATH domain:
|
|
|
|
|
|
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(106 residues)
CATH domain:
|
|
|
|
|
|
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 18
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(107 residues)
CATH domain:
|
|
|
|
|
|
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 17
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(106 residues)
CATH domain:
|
|
|
|
|
|
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 21
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(107 residues)
CATH domain:
|
|
|
|
|
|
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 20
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(107 residues)
CATH domain:
|
|
|
|
|
|
Structure of ring finger protein 165
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf165. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(62 residues)
|
|
|
|
|
|
Structure of ube2d2:rnf165:ub complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf165. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chains:
C, F, I, L
(69 residues)
|
|
|
|
|
|
Structure of ube2d2:rnf165:ub complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf165. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chain:
C
(60 residues)
|
|
|
|
|
|
Crystal structure of ubch5b in complex with the ring-u5br fragment of ao7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: rnf25.
|
|
|
Chain:
B
(110 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ubch5b in complex with the ring-u5br fragment of ao7 (y165a)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: rnf25.
|
|
|
Chain:
B
(111 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ubch5b in complex with the ring-u5br fragment of ao7 (p199a)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: rnf25.
|
|
|
Chain:
B
(110 residues)
CATH domain:
|
|
|
|
|
|
A c2hc zinc finger is essential for the activity of the ring ubiquitin ligase rnf125
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf125. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: plyss
|
|
|
Chains:
A, B
(96 residues)
CATH domain:
|
|
|
|
|
|
Mini trim5 b-box 2 dimer c2 crystal form
|
|
|
Source: Macaca mulatta, thermus thermophilus (strain hb27 / atcc baa-163 / dsm 7039). Rhesus macaque. Organism_taxid: 9544, 262724. Strain: hb27 / atcc baa-163 / dsm 7039. Gene: trim5, sers, tt_c0520. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, D
(134 residues)
|
|
|
|
|
|
Trim25 ring domain in complex with ubc13-ub conjugate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2n, blu. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Expression_system_taxid: 562
|
|
|
Chains:
F, G
(76 residues)
CATH domain:
|
|
|
|
|
|
X-ray structure of roquin roq domain in complex with a selex-derived hexa-loop RNA motif
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rc3h1, gm551, kiaa2025. Expressed in: escherichia coli. Expression_system_taxid: 562. Expressed in: mus musculus. Expression_system_taxid: 10090
|
|
|
Chains:
A, C, E, G
(152 residues)
CATH domain:
|
|
|
|
|
|
X-ray structure of roquin roq domain in complex with ox40 hexa-loop RNA motif
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rc3h1, gm551, kiaa2025. Expressed in: escherichia coli. Expression_system_taxid: 562. Expressed in: mus musculus. Expression_system_taxid: 10090
|
|
|
Chains:
A, B
(148 residues)
CATH domain:
|
|
|
|
|
|
Trim5 b-box2 and coiled-coil chimera
|
|
|
Source: Macaca mulatta, thermus thermophilus (strain hb27 / atcc baa-163 / dsm 7039). Rhesus macaque. Organism_taxid: 9544, 262724. Strain: hb27 / atcc baa-163 / dsm 7039. Gene: trim5, sers, tt_c0520. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
E, F, H, L
(134 residues)
|
|
|
|
|
|
Complex of trim25 ring with ubch5-ub
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim25, efp, rnf147, znf147. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ube2d1, sft, ubc5a, ubch5, ubch5a. Bos taurus. Bovine.
|
|
|
Chains:
A, D
(79 residues)
CATH domain:
|
|
|
|
|
|
Trim32 ring
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim32, ht2a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(78 residues)
CATH domain:
|
|
|
|
|
|
Structure of the conserved yeast listerin (ltn1) n-terminal domain, monoclinic form
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rkr1, ltn1, ymr247c, ym9408.09c, ym9920.01c. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: codon plus ril.
|
|
|
Chains:
A, B
(407 residues)
|
|
|
|
|
|
Structure of the conserved yeast listerin (ltn1) selenomethionine- substituted n-terminal domain, trigonal form
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rkr1, ltn1, ymr247c, ym9408.09c, ym9920.01c. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: methionine auxotroph
|
|
|
Chain:
A
(406 residues)
|
|
|
|
|
|
Crystal structure of usp7 with rnf169 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
E, H
(11 residues)
|
|
|
|
|
|
Cryo-em structure of the catalytic step i spliceosome (c complex) at 3.4 angstrom resolution
|
|
|
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Strain: s288c. Strain: atcc 204508 / s288c. Baker's yeast. Saccharomyces cerevisiae s288c, saccharomyces cerevisiae s288c. Strain: s288c
|
|
|
Chains:
o, p, q, r
(126 residues)
|
|
|
|
|
|
Complex structure of trim24 phd-bromodomain and inhibitor 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
|
|
|
Chains:
A, B, C, D
(172 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of trim24 phd-bromodomain and inhibitor 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
|
|
|
Chains:
B, A, C, D
(174 residues)
CATH domains:
|
|
|
|
|
|
Complex structure of trim24 phd-bromodomain and inhibitor 6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
|
|
|
Chains:
A, B
(169 residues)
CATH domains:
|
|
|
|
|
|
Structural basis of the flanking zinc-finger motifs crucial for the e3 ligase activity of the lnx1 ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lnx1, lnx, pdzrn2, unq574/pro1136. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
D
(124 residues)
|
|
|
|
|
|
Structural basis of the flanking zinc-finger motifs crucial for the e3 ligase activity of the lnx1 ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: lnx1, lnx, pdzrn2, unq574/pro1136. Gene: ube2n, blu. Expression_system_taxid: 562
|
|
|
Chains:
D, B
(124 residues)
|
|
|
|
|
|
Crystal structure of siah2 sbd domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: siah2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(190 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of apo c-cbl tkbd refined to 2.25 a resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C
(302 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of c-cbl tkbd-ring domains (y371e mutant) refined to 1.85 a resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(374 residues)
|
|
|
|
|
|
Crystal structure of c-cbl tkbd domain in complex with spry2 peptide (36-60, py55) refined to 1.8a resolution (p6 form)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: synthesized by new england peptide with an acetylated n-terminus
|
|
|
Chain:
A
(303 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of c-cbl tkbd in complex with spry2 peptide (36-60, py55) refined to 1.8 a resolution (p21 form)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: synthesized by new england peptide with an acetylated n-terminus
|
|
|
Chain:
A
(303 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of c-cbl tkbd in complex with spry2 peptide (54-60, py55) refined to 2.2a resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: synthesized by new england peptide with an acetylated n-terminus
|
|
|
Chain:
A
(303 residues)
|
|
|
|
|
|
Hdm2 in complex with a 3,3-disubstituted piperidine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(95 residues)
CATH domain:
|
|
|
|
|
|
Hdm2 in complex with a 3,3-disubstituted piperidine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(96 residues)
CATH domain:
|
|
|
|
|
|
Hdm2 in complex with a 3,3-disubstituted piperidine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(86 residues)
CATH domain:
|
|
|
|
|
|
Wd40 domain of human e3 ubiquitin ligase cop1 (rfwd2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rfwd2, cop1, rnf200. Expressed in: trichoplusia ni. Expression_system_taxid: 7111
|
|
|
Chain:
A
(324 residues)
CATH domain:
|
|
|
|
|
|
Alternative model of the mage-g1 nse-1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ndnl2, hca4, mageg1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: nsmce1, hspc333, hspc337. Expression_system_taxid: 562
|
|
|
Chain:
C
(236 residues)
CATH domains:
|
|
|
|
|
|
Nmr structure of uhrf1 tandem tudor domains in a complex with spacer peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(152 residues)
CATH domains:
|
|
|
|
|
|
Trim5 b-box2 and coiled-coil chimera
|
|
|
Source: Macaca mulatta, thermus thermophilus (strain hb27 / atcc baa-163 / dsm 7039). Rhesus macaque. Organism_taxid: 9544, 262724. Strain: hb27 / atcc baa-163 / dsm 7039. Gene: trim5, sers, tt_c0520. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, F, K
(118 residues)
|
|
|
|
|
|
Wd40 domain of arabidopsis thaliana e3 ubiquitin ligase cop1 in complex with peptide from trib1
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Synthetic: yes. Homo sapiens. Human.
|
|
|
Chains:
A, B, C, D
(321 residues)
CATH domain:
|
|
|
|
|
|
Wd40 domain of human e3 ubiquitin ligase cop1 (rfwd2) bound to peptide from trib1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rfwd2, cop1, rnf200. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D, E, F
(324 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the microtubule-targeting cos domain of mid1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mid1, fxy, rnf59, trim18, xprf. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chain:
A
(60 residues)
|
|
|
|
|
|
Structure of c-cbl y371f
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F
(386 residues)
CATH domains:
|
|
|
|
|
|
Structure of mdm2 with low molecular weight inhibitor with aliphatic linker.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(101 residues)
|
|
|
|
|
|
Structure of mdm2 with low molecular weight inhibitor with aliphatic linker.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(94 residues)
|
|
|
|
|
|
Solution structure of the trim21 b-box2 (b2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim21, rnf81, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(45 residues)
|
|
|
|
|
|
Crystal structure of sopa-trim56 complex
|
|
|
Source: Salmonella enterica subsp. Enterica serovar typhimurium. Organism_taxid: 90371. Gene: sopa, stm2066. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
B
(61 residues)
|
|
|
|
|
|
Rhesus macaques trim5alpha bbox2 domain
|
|
|
Source: Macaca mulatta. Rhesus macaque. Organism_taxid: 9544. Gene: trim5. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(43 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of the hltf hiran domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hltf, hip116a, rnf80, smarca3, snf2l3, zbu1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(122 residues)
|
|
|
|
|
|
Shigella flexneri effector ipah1880
|
|
|
Source: Shigella flexneri. Organism_taxid: 623. Gene: ipah_4, sf1880. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(554 residues)
|
|
|
|
|
|
The wd domain ofarabidopsis thaliana e3 ubiquitin ligase cop1 in complex with peptide from hy5
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Synthetic: yes. Arabidopsis. Organism_taxid: 3701
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Novel spiro[3h-indole-3,2 -pyrrolidin]-2(1h)-one inhibitors of the mdm2-p53 interaction: hdm2 (mdm2) in complex with compound 6b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(93 residues)
CATH domain:
|
|
|
|
|
|
Novel spiro[3h-indole-3,2 -pyrrolidin]-2(1h)-one inhibitors of the mdm2-p53 interaction: hdm2 (mdm2) in complex with compound 14
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: external
|
|
|
Chain:
A
(94 residues)
CATH domain:
|
|
|
|
|
|
Discovery of new natural-product-inspired spiro-oxindole compounds as orally active inhibitors of the mdm2-p53 interaction: hdm2 (mdm2) in complex with compound 6g
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: external
|
|
|
Chains:
A, B, C, D, E, F
(95 residues)
CATH domain:
|
|
|
|
|
|
Novel spiro[3h-indole-3,2 -pyrrolidin]-2(1h)-one inhibitors of the mdm2-p53 interaction: hdm2 (mdm2) in complex with compound bi-0252
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: external
|
|
|
Chain:
A
(94 residues)
CATH domain:
|
|
|
|
|
|
Solution nmr structure of tryptophan to alanine mutant of arkadia ring domain.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf111. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(69 residues)
|
|
|
|
|
|
Solution nmr structure of tryptophan to arginine mutant of arkadia ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf111. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(69 residues)
|
|
|
|
|
|
Overall structure of the yeast spliceosome immediately after branching.
|
|
|
Source: Saccharomyces cerevisiae. Organism_taxid: 4932. Organism_taxid: 4932
|
|
|
Chains:
t, u, v, w
(438 residues)
|
|
|
|
|
|
Discovery of a novel class of highly potent inhibitors of the p53-mdm2 interaction by structure-based design starting from a conformational argument
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(95 residues)
CATH domain:
|
|
|
|
|
|
A caf40-binding motif facilitates recruitment of the ccr4-not complex to mrnas targeted by drosophila roquin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rqcd1, cnot9, rcd1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: star. Synthetic: yes. Drosophila melanogaster.
|
|
|
Chains:
B, D
(21 residues)
|
|
|
|
|
|
Small molecule inhibitors of iap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(106 residues)
|
|
|
|
|
|
Small molecule inhibitors of iap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(105 residues)
|
|
|
|
|
|
Small molecule inhibitors of iap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(104 residues)
|
|
|
|
|
|
Small molecule inhibitors of iap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(105 residues)
|
|
|
|
|
|
Small molecule inhibitors of iap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(104 residues)
|
|
|
|
|
|
Small molecule inhibitors of iap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(100 residues)
|
|
|
|
|
|
Spliceosome component
|
|
|
Source: Chaetomium thermophilum (strain dsm 1495 / cbs 144.50 / imi 039719). Organism_taxid: 759272. Gene: ctht_0072540. Expressed in: chaetomium thermophilum. Expression_system_taxid: 209285
|
|
|
Chains:
A, B
(121 residues)
|
|
|
|
|
|
Spliceosome component
|
|
|
Source: Chaetomium thermophilum. Organism_taxid: 209285. Gene: ctht_0072540. Expressed in: chaetomium thermophilum. Expression_system_taxid: 209285
|
|
|
Chains:
A, B
(326 residues)
|
|
|
|
|
|
Spliceosome component
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: prp19, pso4, yll036c. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
|
|
|
Chains:
A, B
(353 residues)
|
|
|
|
|
|
Structure of mdm2-mdmx-ubch5b-ubiquitin complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Gene: mdm2. Gene: mdm4, mdmx.
|
|
|
Chains:
C, G
(63 residues)
|
|
|
|
|
|
Structure of a spliceosome remodeled for exon ligation
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: in vitro transcription vector pt7-fluc(deltai). Expression_system_taxid: 905932. Organism_taxid: 4932
|
|
|
Chains:
t, u, v, w
(438 residues)
|
|
|
|
Bound ligand:
|
Het Group GTP
is 96.88% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Cryo-em structure of a human spliceosome activated for step 2 of splicing (c Complex)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chains:
G, H, I, J
(132 residues)
|
|
|
|
|
|
Crystal structure of trim33 phd-bromodomain isoform b in complex with h3k9ac histone peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim33, kiaa1113, rfg7, tif1g. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(186 residues)
|
|
|
|
|
|
Crystal structure of the cul2-rbx1-elobc-vhl ubiquitin ligase complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21. Gene: vhl. Expressed in: escherichia coli.
|
|
|
Chain:
R
(86 residues)
|
|
|
|
|
|
Complex of influenza a ns1 effector domain with trim25 coiled coil
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim25, efp, rnf147, znf147. Expressed in: escherichia coli. Expression_system_taxid: 562. Influenza a virus (strain a/puerto rico/8/1934 h1n1). Organism_taxid: 211044.
|
|
|
Chains:
A, E, I
(173 residues)
|
|
|
|
|
|
Complex of influenza a ns1 with trim25 coiled coil domain
|
|
|
Source: Influenza a virus (strain a/puerto rico/8/1934 h1n1). Organism_taxid: 211044. Strain: a/puerto rico/8/1934 h1n1. Gene: ns. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
|
|
|
Chains:
I, A, V, N
(173 residues)
|
|
|
|
|
|
Birc4 ring in complex with dimeric ubiquitin variant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ubb. Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(64 residues)
|
|
|
|
|
|
Ube4b u-box domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube4b, hdnb1, kiaa0684, ufd2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(71 residues)
|
|
|
|
|
|
Structure of phosphoy371 c-cbl in complex with zap70-peptide and ubv.Pcbl ubiquitin variant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Expression_system_taxid: 469008
|
|
|
Chains:
A, C
(385 residues)
|
|
|
|
|
|
Structure of mdm2 with low molecular weight inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(97 residues)
|
|
|
|
|
|
Hdm2 (17-111, wild type) complexed with nvp-hdm201 at 1.56a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(93 residues)
|
|
|
|
|
|
Trim21
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim21, rnf81, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(125 residues)
|
|
|
|
|
|
Xiap in complex with small molecule
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(106 residues)
|
|
|
|
|
|
Crystal structure of p53 epitope-scaffold based on a inhibitor of cysteine proteases in complex with human mdm2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Entamoeba histolytica. Organism_taxid: 5759. Gene: ams, icp1.
|
|
|
Chains:
A, B
(84 residues)
|
|
|
|
|
|
Crystal structure of the ubr-box domain from ubr2 in complex with rlws n-degron
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr2, c6orf133, kiaa0349. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(71 residues)
|
|
|
|
|
|
Crystal structure of the human ubr-box domain from ubr2 in complex with asymmetrically double methylated arginine peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr2, c6orf133, kiaa0349. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(70 residues)
|
|
|
|
|
|
Crystal structure of the human ubr-box domain from ubr1 in complex with monomethylated arginine peptide.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, C
(70 residues)
|
|
|
|
|
|
Human ubr-box from ubr2 in complex with hifs peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr2, c6orf133, kiaa0349. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(72 residues)
|
|
|
|
|
|
Crystal structure of the rnf20 ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf20, bre1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(69 residues)
CATH domain:
|
|
|
|
|
|
Mdm2 in complex with sar405838
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E
(98 residues)
CATH domain:
|
|
|
|
|
|
Structure of rnf165 in complex with a ubch5b~ub conjugate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_cell_line: bl21. Gene: ubb. Gene: rnf165.
|
|
|
Chain:
C
(51 residues)
|
|
|
|
|
|
Crystal structure of rnf165 in complex with a ubch5b~ub conjugate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_cell_line: bl21. Gene: ubb. Gene: rnf165.
|
|
|
Chain:
C
(49 residues)
|
|
|
|
|
|
Crystal structure of the v122l mutant of human ubr-box domain from ubr2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr2, c6orf133, kiaa0349. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(72 residues)
|
|
|
|
|
|
Crystal structure of human mdm2 in complex with 12-mer peptide inhibitor m3
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, C
(82 residues)
|
|
|
|
|
|
Cryoem structure of the erad-associated e3 ubiquitin-protein ligase hrd1
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Atcc: 204508 /s288c. Gene: hrd1, der3, yol013c. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932.
|
|
|
Chains:
A, B
(270 residues)
|
|
|
|
|
|
Trim-cyclophilin a b-box 2 and coiled-coil chimera
|
|
|
Source: Aotus trivirgatus, thermus thermophilus (strain hb27 / atcc baa-163 / dsm 7039). Three-striped night monkey. Organism_taxid: 9505, 262724. Strain: hb27 / atcc baa-163 / dsm 7039. Gene: sers, tt_c0520. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(123 residues)
|
|
|
|
|
|
Solution nmr structure of histone h2a-h2b mono-ubiquitylated at h2a lys15 in complex with rnf169 (653-708)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hist1h2bj, h2bfr, hist1h2ab, h2afm, hist1h2ae, h2afa. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubb. Expression_system_taxid: 562. Gene: rnf169, kiaa1991.
|
|
|
Chain:
C
(59 residues)
|
|
|
|
|
|
Solution nmr structure of human rad18 (198-240) in complex with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rad18, rnf73.
|
|
|
Chain:
B
(43 residues)
|
|
|
|
|
|
Crystal structure of human mdm2 in complex with a 12-mer lysine- cysteine side chain dithiocarbamate stapled peptide inhibitor pmi
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, C, E, G, I, K, M, O, Q, S, U, W
(85 residues)
|
|
|
|
|
|
Structure of a traf6-ubc13~ub complex
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Gene: traf6, si:dkey-56p7.3, zgc:63704. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, D
(108 residues)
|
|
|
|
|
|
Structure of a traf6-ubc13~ub complex
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Gene: traf6, si:dkey-56p7.3, zgc:63704. Expressed in: escherichia coli. Expression_system_taxid: 511693. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, D
(104 residues)
|
|
|
|
|
|
Trim23 ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim23, ard1, arfd1, rnf46. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(77 residues)
|
|
|
|
|
|
Trim23 ring domain in complex with ubch5-ub
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: trim23, ard1, arfd1, rnf46.
|
|
|
Chains:
F, G
(77 residues)
|
|
|
|
|
|
The structure of the trim5alpha bbox- coiled coil in complex lc3b
|
|
|
Source: Macaca mulatta. Rhesus macaque. Organism_taxid: 9544. Gene: trim5. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, B
(193 residues)
|
|
|
|
|
|
Cryo-em structure of the catalytic step ii spliceosome (c Complex) at 4.0 angstrom resolution
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Saccharomyces cerevisiae s288c. S288c), saccharomyces cerevisiae s288c. Saccharomyces cerevisiae s288c, saccharomyces cerevisiae (strain atcc 204508 / s288c).
|
|
|
Chains:
o, p, q, r
(126 residues)
|
|
|
|
|
|
Green fluorescent protein linked mtide-02 inhibitor in complex with mdm2
|
|
|
Source: Aequorea victoria, camelus dromedarius. Jellyfish. Organism_taxid: 6100, 9838. Gene: gfp. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
B
(96 residues)
|
|
|
|
|
|
Crystal structure of the kh1 domain of human RNA-binding e3 ubiquitin- protein ligase mex-3c complex with RNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mex3c, rkhd2, rnf194, bm-013. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(94 residues)
|
|
|
|
|
|
Crystal structure of the kh2 domain of human RNA-binding e3 ubiquitin- protein ligase mex-3c complex with RNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mex3c, rkhd2, rnf194, bm-013. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(84 residues)
|
|
|
|
|
|
Crystal structure of the kh2 domain of human RNA-binding e3 ubiquitin- protein ligase mex-3c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mex3c, rkhd2, rnf194, bm-013. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A, C
(80 residues)
|
|
|
|
|
|
Crystal structure of mageg1 and nse1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: nsmce3, hca4, mageg1, ndnl2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: nsmce1, hspc333, hspc337.
|
|
|
Chain:
A
(236 residues)
|
|
|
|
|
|
The siah e3 ubiquitin ligases promote wnt/ beta-catenin signaling through mediating wnt-induced axin degradation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: siah1, humsiah. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Gene: axin1, axin.
|
|
|
Chains:
A, B, C, D
(190 residues)
|
|
|
|
|
|
Crystal structure of rnf168 udm1 in complex with lys63-linked diubiquitin, form i
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168. Expressed in: escherichia coli. Expression_system_taxid: 562. Mus musculus. Mouse. Organism_taxid: 10090.
|
|
|
Chains:
A, D
(79 residues)
|
|
|
|
|
|
Crystal structure of rnf168 udm1 in complex with lys63-linked diubiquitin, form ii
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rps27a, uba80, ubcep1. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
E, A
(75 residues)
|
|
|
|
|
|
Crystal structure of rnf168 udm2 in complex with lys63-linked diubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168. Expressed in: escherichia coli. Expression_system_taxid: 562. Mus musculus. Mouse. Organism_taxid: 10090.
|
|
|
Chain:
A
(47 residues)
|
|
|
|
|
|
Structure of uhrf1 ttd in complex with nv01
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(140 residues)
|
|
|
|
|
|
Crystal structure of al2 pal domain in complex with atring1a distal site
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: al2, at3g11200, f11b9.12, f9f8.2. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Synthetic: yes. Organism_taxid: 3702
|
|
|
Chains:
D, F
(12 residues)
|
|
|
|
|
|
Structure-activity studies of mdm2/mdm4-binding stapled peptides comprising non-natural amino acids
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Phage display vector ptdisp. Organism_taxid: 279974
|
|
|
Chains:
A, B
(95 residues)
|
|
|
|
|
|
Crystal structure of al2 pal domain in complex with atring1a proximal site
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: al2, at3g11200, f11b9.12, f9f8.2. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Synthetic: yes. Organism_taxid: 3702
|
|
|
Chain:
C
(12 residues)
|
|
|
|
|
|
Cryo-em structure of the intron-lariat spliceosome ready for disassembly from s.Cerevisiae at 3.5 angstrom
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Saccharomyces cerevisiae s288c. Strain: atcc 204508 / s288c
|
|
|
Chains:
q, r, s, t
(126 residues)
|
|
|
|
|
|
Traf4_gpib complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf4, cart1, mln62, rnf83. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D, E, F
(158 residues)
|
|
|
|
|
|
Crystal structure of rnf168 udm1 in complex with lys63-linked diubiquitin, tetrameric form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba80, ubcep1. Expression_system_taxid: 562
|
|
|
Chains:
A, G, F, L
(81 residues)
|
|
|
|
|
|
Cryo-em structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6 angstrom
|
|
|
Source: Saccharomyces cerevisiae s288c. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Strain: atcc 204508 / s288c
|
|
|
Chains:
q, r, s, t
(129 residues)
|
|
|
|
|
|
Crystal structure of ring e3 ligase znrf1 in complex with ube2n (ubc13)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2n, blu. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: znrf1, nin283.
|
|
|
Chain:
B
(87 residues)
|
|
|
|
|
|
Crystal structure of tandem tudor domain of human uhrf1 in complex with lig1-k126me3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(137 residues)
|
|
|
|
|
|
Crystal structure of tandem tudor domain of human uhrf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(160 residues)
|
|
|
|
|
|
Crystal structure of his6-tagged mdm2 with nutlin-3a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(88 residues)
|
|
|
|
|
|
Cryo-em structure of a human activated spliceosome (early bact) at 4.9 angstrom.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Synthetic: yes. Unidentified adenovirus. Organism_taxid: 10535. Organism_taxid: 9606
|
|
|
Chain:
M
(36 residues)
|
|
|
|
|
|
Crystal structure of pa-tm-ring e3 ligase rnf13 ring domain in complex with e2~ub
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf13, rzf.
|
|
|
Chains:
A, D
(74 residues)
|
|
|
|
|
|
Crystal structure of rnf13 ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf13, rzf. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, D
(73 residues)
|
|
|
|
|
|
Hairpin forming complex, rag1/2-nicked 12rss/23rss complex in ca2+
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t. Gene: rag2, rag-2. Gene: hmgb1, hmg-1, hmg1.
|
|
|
Chains:
A, C
(618 residues)
|
|
|
|
|
|
Hairpin forming complex, rag1/2-nicked(with dideoxy) 12rss/23rss complex in mg2+
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t. Gene: rag2, rag-2. Expression_system_cell_line: het293t.
|
|
|
Chains:
A, C
(618 residues)
|
|
|
|
|
|
Hairpin forming complex, rag1/2-nicked 12rss/23rss complex in 2mm mn2+ for 10 min at 4'c
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t. Gene: rag2, rag-2. Expression_system_cell_line: het293t.
|
|
|
Chains:
A, C
(618 residues)
|
|
|
|
|
|
Hairpin complex, rag1/2-hairpin 12rss/23rss complex in 5mm mn2+ for 2 min at 4'c
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: het293t. Gene: rag2, rag-2. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, C
(618 residues)
|
|
|
|
|
|
The ring domain structure of mex-3c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mex3c. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chains:
A, B, C, D, E, F, G, H
(55 residues)
|
|
|
|
|
|
Binding and enhanced binding between key immunity proteins traf6 and tifa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf6, rnf85. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(153 residues)
|
|
|
|
|
|
The 1.25a crystal structure of his6-tagged mdm2 in complex with nutlin-3a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333
|
|
|
Chain:
A
(87 residues)
|
|
|
|
|
|
Binding and enhanced binding between key immunity proteins traf6 and tifa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf6, rnf85. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(152 residues)
|
|
|
|
|
|
Zinc finger domain from the hrd1 protein
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
|
|
|
Chain:
A
(56 residues)
|
|
|
|
|
|
Mdm2 in complex with a d amino acid containing stapled peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Enterobacteria phage m13. Organism_taxid: 10870
|
|
|
Chain:
A
(86 residues)
|
|
|
|
|
|
Bbragl-3'tir synaptic complex with nicked DNA refined with c2 symmetry
|
|
|
Source: Branchiostoma belcheri. Amphioxus. Organism_taxid: 7741. Gene: rag1l. Expressed in: homo sapiens. Expression_system_taxid: 9606. Synthetic: yes. Gene: rag2l. Expression_system_taxid: 9606
|
|
|
Chains:
A, E
(553 residues)
|
|
|
|
|
|
Crystal structure of uhrf1 ttd domain in complex with the polybasic region
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Gene: uhrf1. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, B, C, D
(150 residues)
|
|
|
|
|
|
Inactive choanoflagellate e3 ubiquitin ligase cbl tkb
|
|
|
Source: Salpingoeca rosetta (strain atcc 50818 / bsb- 021). Organism_taxid: 946362. Strain: atcc 50818 / bsb-021. Gene: ptsg_09506. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(323 residues)
|
|
|
|
|
|
S. Cerevisiae spliceosomal post-catalytic p complex
|
|
|
Source: Saccharomyces cerevisiae. Organism_taxid: 4932. Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Strain: atcc 204508 / s288c
|
|
|
Chains:
u, v, w, x
(435 residues)
|
|
|
|
|
|
Rnf146 tbm-tankyrase arc2-3 complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Variant: tankyrase 1. Gene: tnks, tnks1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Homo sapiens.
|
|
|
Chain:
C
(12 residues)
|
|
|
|
|
|
Cryo-em structure of mouse rag1/2 hfc complex (3.17 a)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli k-12.
|
|
|
Chains:
A, C
(614 residues)
|
|
|
|
|
|
Cryo-em structure of mouse rag1/2 hfc complex containing partial hmgb1 linker(3.9 a)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Synthetic: yes. Homo sapiens. Organism_taxid: 9606.
|
|
|
Chains:
A, C
(614 residues)
|
|
|
|
|
|
Pre-reaction complex, rag1(e962q)/2-intact/nicked 12/23rss complex in mn2+
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Expression_system_cell_line: hek 293t. Homo sapiens.
|
|
|
Chains:
A, C
(607 residues)
|
|
|
|
|
|
Pre-reaction complex, rag1(e962q)/2-intact/intact 12/23rss complex in mn2+
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Homo sapiens. Human.
|
|
|
Chains:
A, C
(585 residues)
|
|
|
|
|
|
Pre-reaction complex, rag1(e962q)/2-nicked/intact 12/23rss complex in mn2+
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t. Gene: rag2, rag-2. Homo sapiens.
|
|
|
Chains:
A, C
(611 residues)
|
|
|
|
|
|
Crystal structure of the wd40-repeat of rfwd3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rfwd3, rnf201. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chains:
A, B, C
(337 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with 12-rss and 23-rss nicked DNA intermediates
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
C, A
(622 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with 12-rss and 23-rss nicked DNA intermediates
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
A, C
(552 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with 12-rss and 23-rss substrate dnas
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
A, C
(616 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with 12-rss and 23-rss substrate dnas
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
A, C
(542 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with 12-rss and 23-rss substrate dnas
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
A, C
(621 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with one melted rss and one unmelted rss
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
A, C
(550 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with 12-rss and 23-rss substrate dnas
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
A, C
(614 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with 12-rss and 23-rss substrate dnas
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
A, C
(543 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with 12-rss and 23-rss substrate dnas
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
A, C
(616 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with 12-rss substrate DNA
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
A, C
(614 residues)
|
|
|
|
|
|
Cryo-em structure of rag in complex with 12-rss substrate DNA
|
|
|
Source: Escherichia coli, danio rerio. Zebrafish. Organism_taxid: 83333, 7955. Strain: k12. Gene: male, b4034, jw3994, rag1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Danio rerio. Organism_taxid: 7955.
|
|
|
Chains:
A, C
(615 residues)
|
|
|
|
|
|
Crystal structure of ebola virus vp30 c-terminus/rbbp6 peptide complex
|
|
|
Source: Zaire ebolavirus (strain kikwit-95). Zebov. Organism_taxid: 128951. Strain: kikwit-95. Gene: vp30. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Homo sapiens.
|
|
|
Chain:
B
(13 residues)
|
|
|
|
|
|
Crystal structure of the human chip tpr domain in complex with a 5mer acetylated hsp70 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(132 residues)
|
|
|
|
|
|
Post-catalytic p complex spliceosome with 3' splice site docked
|
|
|
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Baker's yeast. Saccharomyces cerevisiae (strain atcc 204508 / s288c). Strain: atcc 204508 / s288c. Expressed in: transcription vector puc18-pes2. Expression_system_taxid: 118293. Saccharomyces cerevisiae.
|
|
|
Chains:
t, u, v, w
(117 residues)
|
|
|
|
Bound ligand:
|
Het Group GTP
is 96.88% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Crystal structure of ciap1-bir3 in complex with a covalently bound sm
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, C
(98 residues)
|
|
|
|
|
|
Crystal structure of xiap-bir3 in complex with a ciap1-selective sm
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F, G, H
(99 residues)
|
|
|
|
|
|
Human bact spliceosome core structure
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: hela s3. Cell_line: hela s3
|
|
|
Chain:
t
(172 residues)
|
|
|
|
|
|
Human bact spliceosome core structure
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chains:
t, G, H, I, J
(172 residues)
|
|
|
|
|
|
Crystal structure of trim21 e3 ligase, ring domain in complex with its cognate e2 conjugating enzyme ube2e1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim21, rnf81, ro52, ssa1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Expression_system_variant: ros-2. Gene: ube2e1, ubch6. Expression_system_variant: ros-2
|
|
|
Chains:
A, B, C, D, E, F, G, H
(76 residues)
|
|
|
|
|
|
Crystal structure of the human trim25 pryspry domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim25, efp, rnf147, znf147. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chains:
A, B, C
(198 residues)
|
|
|
|
|
|
Crystal structure of the human trim25 coiled-coil and pryspry domains
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim25, efp, rnf147, znf147. Expressed in: trichoplusia ni. Expression_system_taxid: 7111
|
|
|
Chains:
A, B, E
(366 residues)
|
|
|
|
|
|
Crystal structure of danio rerio lin41 filamin-nhl domains
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Gene: trim71, lin41. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
|
|
|
Chains:
A, B
(391 residues)
|
|
|
|
|
|
Crystal structure of danio rerio lin41 filamin-nhl domains in complex with lin-29a 5'utr 13mer RNA
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Gene: trim71, lin41. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Caenorhabditis elegans. Organism_taxid: 6239.
|
|
|
Chain:
A
(390 residues)
|
|
|
|
|
|
Crystal structure of danio rerio lin41 filamin-nhl domains in complex with mab-10 3'utr 13mer RNA
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Gene: trim71, lin41. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_variant: sf9. Synthetic: yes. Caenorhabditis elegans.
|
|
|
Chain:
A
(390 residues)
|
|
|
|
|
|
In vitro and in vivo characterization of a novel, highly potent p53- mdm2 inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(94 residues)
|
|
|
|
|
|
Structure of xiap-bir1 domain in complex with an nf023 analog
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B, C, D
(78 residues)
|
|
|
|
|
|
Crystal structure of mdm2 bound to a stapled peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(91 residues)
|
|
|
|
|
|
Crystal structure of the kap1 rbcc domain in complex with the smarcad1 cue1 domain.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: smarcad1, kiaa1122. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: trim28, kap1, rnf96, tif1b. Expression_system_taxid: 562
|
|
|
Chains:
A, F
(266 residues)
|
|
|
|
|
|
Fragment derived xiap inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(106 residues)
|
|
|
|
|
|
Fragment derived xiap inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(107 residues)
|
|
|
|
|
|
Crystal structure of hdm2 in complex with a c-terminal triurea capped peptide chimera foldamer.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(87 residues)
|
|
|
|
|
|
Drosophila not4 cbm peptide bound to human caf40
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cnot9, rcd1, rqcd1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: star. Synthetic: yes. Drosophila melanogaster.
|
|
|
Chains:
B, D
(25 residues)
|
|
|
|
|
|
Drosophila not4 cbm peptide bound to human caf40
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cnot9, rcd1, rqcd1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: star. Synthetic: yes. Drosophila melanogaster.
|
|
|
Chains:
B, D
(25 residues)
|
|
|
|
|
|
Crystal structure of ciap1 ring domain bound to ubch5b-ub and a non- covalent ub
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expression_system_taxid: 562
|
|
|
Chain:
A
(63 residues)
|
|
|
|
|
|
X-ray structure of the p53-mdm2 inhibitor nmi801 bound to hdm2 at 2.1a resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(93 residues)
|
|
|
|
|
|
Crystal structure of mdm2 in complex with compound 13.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(94 residues)
|
|
|
|
|
|
Solution structure of trim28 ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim28, kap1, rnf96, tif1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(92 residues)
|
|
|
|
|
|
Cryo-em structure of a human post-catalytic spliceosome (p complex) at 3.0 angstrom
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chains:
q, r, s, t
(132 residues)
|
|
|
|
|
|
Cryo-em structure of a human intron lariat spliceosome prior to prp43 loaded (ils1 complex) at 2.9 angstrom resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chains:
q, r, s, t
(132 residues)
|
|
|
|
|
|
Cryo-em structure of a human intron lariat spliceosome after prp43 loaded (ils2 complex) at 2.9 angstrom resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
|
|
|
Chains:
q, r, s, t
(132 residues)
|
|
|
|
|
|
Crystal structure of human uhrf1 phd finger in complex with paf15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(66 residues)
|
|
|
|
|
|
Mdm2 bound cueo-pm2 sensor
|
|
|
Source: Escherichia coli (strain k12), synthetic construct. Organism_taxid: 83333, 32630. Strain: k12. Gene: cueo, yack, b0123, jw0119. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
|
|
|
Chain:
B
(87 residues)
|
|
|
|
|
|
Zinc finger domain of the human dtx protein
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
|
|
|
Chain:
A
(76 residues)
|
|
|
|
|
|
Cryo-em structure of the yeast b -A2 complex at an average resolution of 3.2 angstrom
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Saccharomyces cerevisiae s288c. Strain: s288c. Strain: atcc 204508 / s288c
|
|
|
Chains:
r, p, q, o
(125 residues)
|
|
|
|
|
|
Cryo-em structure of the yeast b -A1 complex at an average resolution of 3.6 angstrom
|
|
|
Source: Saccharomyces cerevisiae s288c. Baker's yeast. Organism_taxid: 559292. Saccharomyces cerevisiae (strain atcc 204508 / s288c). Strain: atcc 204508 / s288c. Strain: s288c. Strain: atcc 204508 / s288c
|
|
|
Chains:
r, p, q, o
(125 residues)
|
|
|
|
|
|
Cryo-em structure of the yeast b -B1 complex at an average resolution of 3.86 angstrom
|
|
|
Source: Saccharomyces cerevisiae s288c. Baker's yeast. Organism_taxid: 559292. Strain: s288c. Strain: s288c
|
|
|
Chains:
r, p, q, o
(125 residues)
|
|
|
|
|
|
Cryo-em structure of the yeast b -B2 complex at an average resolution of 3.7 angstrom
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Synthetic: yes. Saccharomyces cerevisiae s288c. Strain: atcc 204508 / s288c
|
|
|
Chains:
r, p, q, o
(125 residues)
|
|
|
|
|
|
Sumo1 bound to sls4-sim peptide from icp0
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: sumo1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Human herpesvirus 1. Organism_taxid: 10298
|
|
|
Chain:
B
(12 residues)
|
|
|
|
|
|
Sumo1 bound to phosphorylated sls4-sim peptide from icp0
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: sumo1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Human alphaherpesvirus 1 strain 17. Organism_taxid: 10299
|
|
|
Chain:
B
(12 residues)
|
|
|
|
|
|
Complex of sumo2 bound sls4 from icp0.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: sumo2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Human herpesvirus 1. Organism_taxid: 10298
|
|
|
Chain:
B
(12 residues)
|
|
|
|
|
|
Sumo2 bound to phosphorylated sls4-sim peptide from icp0
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: sumo2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Human alphaherpesvirus 1 strain 17. Organism_taxid: 10299
|
|
|
Chain:
B
(12 residues)
|
|
|
|
|
|
The crystal structure of gbp1 with lrr domain of ipah9.8
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gbp1. Expressed in: escherichia coli. Expression_system_taxid: 562. Shigella flexneri. Organism_taxid: 623. Gene: ipah9.8, cp0226, pwr501_0234, sflp090.
|
|
|
Chain:
B
(214 residues)
|
|
|
|
|
|
Solution structure of mul1-ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mul1, c1orf166, gide, mapl, mulan, rnf218. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(57 residues)
|
|
|
|
|
|
Rglg1 mutant-d338a e378a
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg1, at3g01650, f4p13.19. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(282 residues)
|
|
|
|
|
|
Structure of rglg1 mutant-d207g
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg1, at3g01650, f4p13.19. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A, C, D, E, F, G, H
(280 residues)
|
|
|
|
|
|
The closed state of rglg1 mutant-d338a
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg1, at3g01650, f4p13.19. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(282 residues)
|
|
|
|
|
|
The closed state of rglg1 mutant-e378a
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg1, at3g01650, f4p13.19. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(281 residues)
|
|
|
|
|
|
The closed state of rglg1 vwa domain with midas is occupied by water
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg1, at3g01650, f4p13.19. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(282 residues)
|
|
|
|
|
|
Rglg1 midas binds calcium ion
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg1, at3g01650, f4p13.19. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(227 residues)
|
|
|
|
|
|
The closed state of rglg1 vwa domain
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg1, at3g01650, f4p13.19. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(282 residues)
|
|
|
|
|
|
Rglg1 vwa domain with midas is occupied by water
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg1, at3g01650, f4p13.19. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(280 residues)
|
|
|
|
|
|
The open state of rglg1 vwa domain
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg1, at3g01650, f4p13.19. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(280 residues)
|
|
|
|
|
|
Crystal structure of hiran domain of hltf in complex with duplex DNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hltf, hip116a, rnf80, smarca3, snf2l3, zbu1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(117 residues)
|
|
|
|
|
|
Rlgs-yubr1 ubr box
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ubr1, ptr1, ygr184c, g7168. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(86 residues)
|
|
|
|
|
|
Macrocyclization of an all-d linear peptide improves target affinity and imparts cellular activity: a novel stapled alpha-helical peptide modality
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Phage 13. Organism_taxid: 12424
|
|
|
Chain:
A
(85 residues)
|
|
|
|
|
|
Rlgsgg-atprt6 ubr box
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: prt6, cer3, ged1, at5g02310/at5g02300, t1e22.70/t1e22.60. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(76 residues)
|
|
|
|
|
|
The complex structure of ipah9.8-lrr and hgbp1
|
|
|
Source: Shigella flexneri. Organism_taxid: 623. Gene: ipah9.8, nctc9783_05321. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: gbp1.
|
|
|
Chain:
A
(222 residues)
|
|
|
|
|
|
The crystal structure of full length ipah9.8
|
|
|
Source: Shigella flexneri 2002017. Organism_taxid: 591020. Strain: 2002017. Gene: ipah9.8, sfxv_5076. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(466 residues)
|
|
|
|
|
|
Crystal structure of the bard1 brct mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bard1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
B, A
(209 residues)
|
|
|
|
|
|
Distinct mechanism of mul1-ring domain simultaneously recruiting e2 enzyme and the substrate p53-tad domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: mul1, c1orf166, gide, mapl, mulan, rnf218. Expression_system_taxid: 562
|
|
|
Chains:
E, F, G, H
(55 residues)
|
|
|
|
|
|
Mul1-ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mul1, c1orf166, gide, mapl, mulan, rnf218. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(57 residues)
|
|
|
|
|
|
Crystal structure of uhrf1 sra complexed with fully-mchg DNA.
|
|
|
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Mus musculus. Mouse. Organism_taxid: 10090. Gene: uhrf1, np95. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
B, A
(196 residues)
|
|
|
|
|
|
Structure of zebrafish traf6 in complex with sting ctt
|
|
|
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Gene: traf6, si:dkey-56p7.3, zgc:63704. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 7955
|
|
|
Chains:
A, C
(155 residues)
|
|
|
|
|
|
Crystal structure of the human chip tpr domain in complex with a 5mer acetylated optimized peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(128 residues)
|
|
|
|
|
|
Monobody (mc3) bound to tyrosine kinase binding domain of e3 ubiquitin ligase cbl
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Monobody (mc17) bound to tyrosine kinase binding domain of e3 ubiquitin ligase cbl
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chains:
B, A
(302 residues)
|
|
|
|
|
|
Murine trim28 bbox1 domain
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: trim28, kap1, krip1, tif1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(46 residues)
|
|
|
|
|
|
Cryo-em structure of mouse rag1/2 prc complex (dna0)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli k-12.
|
|
|
Chains:
A, C
(606 residues)
|
|
|
|
|
|
Cryo-em structure of mouse rag1/2 prc complex (dna1)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli k-12.
|
|
|
Chains:
A, C
(606 residues)
|
|
|
|
|
|
Cryo-em structure of mouse rag1/2 nfc complex (dna1)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli k-12.
|
|
|
Chains:
A, C
(608 residues)
|
|
|
|
|
|
Cryo-em structure of mouse rag1/2 12rss-nfc/23rss-prc complex (dna1)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli k-12.
|
|
|
Chains:
A, C
(604 residues)
|
|
|
|
|
|
Cryo-em structure of mouse rag1/2 12rss-prc/23rss-nfc complex (dna1)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli k-12.
|
|
|
Chains:
A, C
(606 residues)
|
|
|
|
|
|
Cryo-em structure of mouse rag1/2 nfc complex (dna2)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli k-12.
|
|
|
Chains:
A, C
(608 residues)
|
|
|
|
|
|
Cryo-em structure of mouse rag1/2 stc complex (without nbd domain)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli k-12.
|
|
|
Chains:
A, C
(548 residues)
|
|
|
|
|
|
Cryo-em structure of mouse rag1/2 stc complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli k-12.
|
|
|
Chains:
A, C
(618 residues)
|
|
|
|
|
|
Hdm2 (17-111, wild type) complexed with compound 12 at 1.8a; structural states of hdm2 and hdmx: x-ray elucidation of adaptations and binding interactions for different chemical compound classes
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(87 residues)
|
|
|
|
|
|
Hdm2 (17-111, wild type) complexed with compound 11 at 2.0a; structural states of hdm2 and hdmx: x-ray elucidation of adaptations and binding interactions for different chemical compound classes
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(92 residues)
|
|
|
|
|
|
Hdm2 (17-111, wildtype) complexed with compound 9 at 1.13a; structural states of hdm2 and hdmx: x-ray elucidation of adaptations and binding interactions for different chemical compound classes
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(94 residues)
|
|
|
|
|
|
Hdm2 (17-111, wildtype) complexed with compound 10 at 1.21a; structural states of hdm2 and hdmx: x-ray elucidation of adaptations and binding interactions for different chemical compound classes
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(94 residues)
|
|
|
|
|
|
Structure of the tripartite motif of kap1/trim28
|
|
|
Source: Enterobacteria phage t4, homo sapiens. Bacteriophage t4, human. Organism_taxid: 10665, 9606. Gene: trim28, kap1, rnf96, tif1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(439 residues)
|
|
|
|
|
|
Structure of xiap-bir1 v86e mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: gold plyss ag
|
|
|
Chains:
A, B, C, D
(78 residues)
|
|
|
|
|
|
Idol ferm domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mylip, bzf1, idol, bm-023, pp5242. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: t1r.
|
|
|
Chain:
A
(330 residues)
|
|
|
|
|
|
Idol f3ab subdomain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mylip, bzf1, idol, bm-023, pp5242. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: t1r.
|
|
|
Chains:
A, B, C
(98 residues)
|
|
|
|
|
|
Crystal structure of an arabidopsis wd40 domain in complex with a transcription factor
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Organism_taxid: 3702
|
|
|
Chain:
A
(317 residues)
|
|
|
|
|
|
Crystal structure of an arabidopsis wd40 domain in complex with photoreceptor
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Organism_taxid: 3702
|
|
|
Chain:
A
(304 residues)
|
|
|
|
|
|
Crystal structure of a mutant arabidopsis wd40 domain in complex with a transcription factor
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Organism_taxid: 3702
|
|
|
Chain:
A
(307 residues)
|
|
|
|
|
|
Crystal structure of a mutant arabidopsis wd40 domain in complex with a photoreceptor
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Organism_taxid: 3702
|
|
|
Chain:
A
(304 residues)
|
|
|
|
|
|
Crystal structure of an arabidopsis wd40 domain in complex with a transcription factor homolog
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Thale cress. Organism_taxid: 3702
|
|
|
Chain:
A
(307 residues)
|
|
|
|
|
|
Crystal structure of arabidopsis wd40 domain in complex with a bbx transcription factor
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Organism_taxid: 3702
|
|
|
Chain:
A
(307 residues)
|
|
|
|
|
|
Crystal structure of an arabidopsis wd40 domain in complex with an atypical bhlh transcription factor
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Thale cress. Organism_taxid: 3702
|
|
|
Chain:
A
(305 residues)
|
|
|
|
|
|
Crystal structure of an arabidopsis wd40 domain in complex with a blue light photoreceptor
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Organism_taxid: 3702
|
|
|
Chain:
A
(300 residues)
|
|
|
|
|
|
Crystal structure of an arabidopsis wd40 domain in complex with a flowering transcription factor homolog
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1, at2g32950, t21l14.11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Organism_taxid: 3702
|
|
|
Chain:
A
(305 residues)
|
|
|
|
|
|
Crystal structure of the kap1 rbcc domain in complex with the smarcad1 cue1 domain at 3.7 angstrom resolution.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim28, kap1, rnf96, tif1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: smarcad1, kiaa1122. Expression_system_taxid: 562
|
|
|
Chain:
A
(262 residues)
|
|
|
|
|
|
Structural basis of cullin-2 ring e3 ligase regulation by the cop9 signalosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gps1, cops1, csn1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Gene: cops2, csn2, trip15. Gene: cops3, csn3.
|
|
|
Chain:
R
(86 residues)
|
|
|
|
|
|
Structural basis of cullin-2 ring e3 ligase regulation by the cop9 signalosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gps1, cops1, csn1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: cops2, csn2, trip15. Gene: cops3, csn3. Gene: cops4, csn4.
|
|
|
Chain:
R
(90 residues)
|
|
|
|
|
|
Structural basis of cullin-2 ring e3 ligase regulation by the cop9 signalosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gps1, cops1, csn1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: eloc, tceb1. Gene: cul2. Gene: cops2, csn2, trip15.
|
|
|
Chain:
R
(90 residues)
|
|
|
|
|
|
Structural basis of cullin-2 ring e3 ligase regulation by the cop9 signalosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gps1, cops1, csn1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: cops2, csn2, trip15. Gene: cops3, csn3. Gene: cops4, csn4.
|
|
|
Chain:
R
(85 residues)
|
|
|
|
|
|
Structural basis of cullin-2 ring e3 ligase regulation by the cop9 signalosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gps1, cops1, csn1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: cops4, csn4. Gene: cops8, csn8. Gene: elob, tceb2.
|
|
|
Chain:
R
(86 residues)
|
|
|
|
|
|
Crystal structure of trim21 ring domain in complex with an isopeptide- linked ube2n~ubiquitin conjugate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2n, blu. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
B, A, H, G
(79 residues)
|
|
|
|
|
|
Crystal structure of human mdm2 ring domain homodimer bound to ubch5b- ub
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Gene: rps27a. Expression_system_taxid: 562
|
|
|
Chains:
A, D
(62 residues)
|
|
|
|
|
|
Crystal structure of cat mdm2-s429e ring domain homodimer
|
|
|
Source: Felis catus. Cat. Organism_taxid: 9685. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(63 residues)
|
|
|
|
|
|
Crystal structure of cat mdm2-s429e ring domain bound to ubch5b-ub
|
|
|
Source: Felis catus. Cat. Organism_taxid: 9685. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, D, G, J
(69 residues)
|
|
|
|
|
|
Crystal structure of cat phospho-ser429 mdm2 ring domain bound to ubch5b-ub
|
|
|
Source: Felis catus. Domestic cat. Organism_taxid: 9685. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, D
(64 residues)
|
|
|
|
|
|
Structure of the fanconi anaemia core complex
|
|
|
Source: Gallus gallus. Organism_taxid: 9031. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Chicken. Gene: fancl. Expression_system_taxid: 7108
|
|
|
Chains:
q, Q
(337 residues)
|
|
|
|
|
|
Structure of the fanconi anaemia core subcomplex
|
|
|
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: fancl. Expression_system_taxid: 7108
|
|
|
Chains:
Q, q
(91 residues)
|
|
|
|
|
|
Structure of active gid e3 ubiquitin ligase complex minus gid2 and delta gid9 ring domain
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: vid28, gid5, yil017c. Expressed in: spodoptera aff. Frugiperda 1 bold-2017. Expression_system_taxid: 2449148. Saccharomyces cerevisiae s288c.
|
|
|
Chain:
9
(157 residues)
|
|
|
|
|
|
Multicomponent peptide stapling as a diversity-driven tool for the development of inhibitors of protein-protein interactions
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(85 residues)
|
|
|
|
|
|
Multicomponent peptide stapling as a diversity-driven tool for the development of inhibitors of protein-protein interactions
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(85 residues)
|
|
|
|
|
|
Multicomponent peptide stapling as a diversity-driven tool for the development of inhibitors of protein-protein interactions
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(85 residues)
|
|
|
|
|
|
Mouse rnf213 wild type protein
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rnf213, mystr. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five
|
|
|
Chain:
A
(4416 residues)
|
|
|
|
|
|
Mouse rnf213 mutant r4753k modeling the moyamoya-disease-related human variant r4810k
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rnf213, mystr. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five
|
|
|
Chain:
A
(4417 residues)
|
|
|
|
|
|
X-ray structure of roquin roq domain in complex with a ucp3 cde2 sl RNA motif
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rc3h1, gm551, kiaa2025. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10090
|
|
|
Chains:
A, B, C, D
(152 residues)
|
|
|
|
|
|
X-ray structure of roquin roq domain in complex with a ucp3 cde1 sl RNA motif
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rc3h1, gm551, kiaa2025. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10090
|
|
|
Chain:
A
(153 residues)
|
|
|
|
|
|
Ubiquitin ligation to substrate by a cullin-ring e3 ligase at 3.7a resolution: nedd8-cul1-rbx1 n98r-skp1-monomeric b-trcp1dd-ikba- ub~ube2d2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: btrc, btrcp, fbw1a, fbxw1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: skp1, emc19, ocp2, skp1a, tceb1l. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chain:
R
(79 residues)
|
|
|
|
|
|
Crystal structure of the trim7 b30.2 domain at 1.6 angstrom resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(171 residues)
|
|
|
|
|
|
Crystal structure of trim7 b30.2 domain at 1.8 angstrom resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(173 residues)
|
|
|
|
|
|
Cryo-em structure of mouse wt rag1/2 nfc complex (dna0)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli.
|
|
|
Chain:
A
(541 residues)
|
|
|
|
|
|
Cryo-em structure of cullin5 bound to ring-box protein 2 (cul5-rbx2)
|
|
|
Source: Streptococcus sp. Group g, homo sapiens. Human. Organism_taxid: 1320, 9606. Gene: spg, cul5, vacm1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Mus musculus. Mouse. Organism_taxid: 10090.
|
|
|
Chain:
R
(84 residues)
|
|
|
|
|
|
Sra domain of uhrf1 in complex with DNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -v3r. Synthetic: yes. Synthetic construct.
|
|
|
Chains:
A, B, E
(188 residues)
|
|
|
|
|
|
Solution structure of the ttd and linker region of uhrf1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(168 residues)
|
|
|
|
|
|
Solution structure of the ttd and linker region of mouse uhrf1 (np95)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: uhrf1, np95. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(184 residues)
|
|
|
|
|
|
Solution structure of the phd of mouse uhrf1 (np95)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: uhrf1, np95. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(78 residues)
|
|
|
|
|
|
Cryo-em structure of hrd1/hrd3 monomer
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: hrd1. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: hrd3. Expression_system_taxid: 4932
|
|
|
Chain:
B
(280 residues)
|
|
|
|
|
|
Cryoem structure of hrd1-usa1/der1/hrd3 complex of the expected topology
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: der1. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: hrd1, der3. Gene: hrd3. Gene: usa1.
|
|
|
Chain:
B
(280 residues)
|
|
|
|
|
|
Cryoem structure of hrd1-usa1/der1/hrd3 of the flipped topology
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: usa1. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: der1. Gene: hrd3. Gene: hrd1, der3.
|
|
|
Chain:
B
(280 residues)
|
|
|
|
|
|
Cryoem structure of hrd1/hrd3 part from hrd1-usa1/der1/hrd3 complex
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: hrd1, der3. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: hrd3. Expression_system_taxid: 4932
|
|
|
Chain:
B
(280 residues)
|
|
|
|
|
|
Human uhrf1 ttd domain in complex with a fragment
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(150 residues)
|
|
|
|
|
|
Structure of ciap with compound 15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(87 residues)
|
|
|
|
|
|
Ternary complex structure - btk ciap compound 17
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: btk, agmx1, atk, bpk. Expressed in: spodoptera aff. Frugiperda 2 rz-2014. Expression_system_taxid: 1491790. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
C, D
(93 residues)
|
|
|
|
|
|
Rnf12 ring domain in complex with ube2d2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rlim, rnf12. Expression_system_taxid: 562
|
|
|
Chain:
B
(71 residues)
|
|
|
|
|
|
Ternary complex structure - btk ciap compound 15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: btk, agmx1, atk, bpk. Expressed in: spodoptera aff. Frugiperda 2 rz-2014. Expression_system_taxid: 1491790. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
D, E, F
(92 residues)
|
|
|
|
|
|
Human uhrf1 ttd domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(159 residues)
|
|
|
|
|
|
Rnf12 ring domain in complex with ube2e2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2e2, ubch8. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rlim, rnf12. Expression_system_taxid: 562
|
|
|
Chains:
B, D
(70 residues)
|
|
|
|
|
|
Rnf12 ring domain in complex with a ube2d2~ub conjugate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rlim, rnf12. Gene: ubc. Expression_system_taxid: 562
|
|
|
Chains:
B, E, H
(62 residues)
|
|
|
|
|
|
Mekk1 tog domain (548-867)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: map3k1, mapkkk1, mekk, mekk1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Ring1b-bmi1 fusion in closed conformation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf2, bmi1, pcgf4, rnf51. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(206 residues)
|
|
|
|
|
|
Inhibitor compound-induced confrontational change in ring1b-bmi1 domain structure
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf2, bmi1, pcgf4, rnf51. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(200 residues)
|
|
|
|
|
|
Structure of cbl tyrosine kinase binding domain (tkbd) with c-terminal tail of src-like kinase protein 2 (slap2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Mus musculus. Mouse. Organism_taxid: 10090.
|
|
|
Chains:
A, B
(305 residues)
|
|
|
|
|
|
Structure of rag1 (r848m/e649v)-rag2-DNA strand transfer complex (dynamic-form)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: expi293f. Gene: rag2, rag-2. Synthetic: yes.
|
|
|
Chains:
A, C
(549 residues)
|
|
|
|
|
|
Structure of rag1 (r848m/e649v)-rag2-DNA strand transfer complex (paired-form)
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Organism_taxid: 10090
|
|
|
Chains:
A, C
(550 residues)
|
|
|
|
|
|
Structure of rag1 (r848m/e649v)-rag2-DNA target capture complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Organism_taxid: 10090
|
|
|
Chains:
A, C
(550 residues)
|
|
|
|
|
|
Ring-dtc domains of deltex 2, form 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dtx2, kiaa1528, rnf58. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(227 residues)
|
|
|
|
|
|
Ring-dtc domains of deltex 2, form 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dtx2, kiaa1528, rnf58. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(231 residues)
|
|
|
|
|
|
Ring-dtc domains of deltex 2, bound to adp-ribose
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dtx2, kiaa1528, rnf58. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(227 residues)
|
|
|
|
|
|
Structure of a stapled peptide bound to mdm2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(92 residues)
|
|
|
|
|
|
Ring-dtc domain of deltex1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dtx1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(228 residues)
|
|
|
|
|
|
Ring-dtc domain of deltex1 bound to NAD
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dtx1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(228 residues)
|
|
|
|
|
|
Structure of the trim69 ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim69, rnf36, hsd-34, hsd34. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(89 residues)
|
|
|
|
|
|
Human c complex spliceosome - medium-resolution periphery
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Human. Strain: hela s3. Organism_taxid: 9606
|
|
|
Chains:
G, H, I, J
(132 residues)
|
|
|
|
|
|
Human pre-bact-2 spliceosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: hela. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Organism_taxid: 9606
|
|
|
Chain:
t
(253 residues)
|
|
|
|
|
|
X-ray structure of mdm2 with modified p53 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D, E, F
(90 residues)
|
|
|
|
|
|
Crystal structure of zebrafish mdm2 ring domain homodimer
|
|
|
Source: Danio rerio
|
|
|
Chains:
A, B
(58 residues)
|
|
|
|
|
|
Crystal structure of western clawed frog mdm2 ring domain homodimer
|
|
|
Source: Xenopus tropicalis
|
|
|
Chains:
A, B
(57 residues)
|
|
|
|
|
|
Crystal structure of human mdm2-g443t ring domain homodimer bound to ubch5b-ub (crystal form 1)'
|
|
|
Source: not given
|
|
|
Chains:
A, D
(62 residues)
|
|
|
|
|
|
Crystal structure of human mdm2-g443t ring domain homodimer bound to ubch5b-ub (crystal form 2)'
|
|
|
Source: not given
|
|
|
Chains:
A, D
(62 residues)
|
|
|
|
|
|
Crystal structure of the computationally designed chemically disruptable heterodimer ld6-mdm2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Shigella dysenteriae sd197. Organism_taxid: 300267. Gene: dsbd, sdy_4441.
|
|
|
Chain:
A
(86 residues)
|
|
|
|
|
|
Crystal structure of nhl domain of trim2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim2, kiaa0517, rnf86. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chains:
A, B
(276 residues)
|
|
|
|
|
|
Crystal structure of spry domain of trim9
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim9, kiaa0282, rnf91. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chain:
A
(172 residues)
|
|
|
|
|
|
Ubiquitin ligation to f-box protein substrates by scf-rbr e3-e3 super- assembly: nedd8-cul1-rbx1-skp1-skp2-ckshs1-cyclin a-cdk2-p27- ube2l3~ub~arih1. Transition state 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: arih1, ari, mop6, ubch7bp, hussy-27. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
R
(81 residues)
|
|
|
|
|
|
Ubiquitin ligation to f-box protein substrates by scf-rbr e3-e3 super- assembly: cul1-rbx1-skp1-skp2-ckshs1-p27~ub~arih1. Transition state 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: arih1, ari, mop6, ubch7bp, hussy-27. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
R
(81 residues)
|
|
|
|
|
|
Ubiquitin ligation to f-box protein substrates by scf-rbr e3-e3 super- assembly: nedd8-cul1-rbx1-ube2l3~ub~arih1.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: arih1, ari, mop6, ubch7bp, hussy-27. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
R
(81 residues)
|
|
|
|
|
|
Ubiquitin ligation to f-box protein substrates by scf-rbr e3-e3 super- assembly: cul1-rbx1-arih1 ariadne. Transition state 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: arih1, ari, mop6, ubch7bp, hussy-27. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
R
(81 residues)
|
|
|
|
|
|
Nhl domain of human trim2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim2, kiaa0517, rnf86. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(280 residues)
|
|
|
|
|
|
Nmr2 structure of trim24-bd in complex with a precursor of iacs-9571
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(106 residues)
|
|
|
|
|
|
Crystal structure of monoubiquitinated trim21 ring (ub-ring) in complex with ubiquitin charged ube2n (ube2n~ub) and ube2v2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb, trim21, rnf81, ro52, ssa1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: ubc. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
B
(160 residues)
|
|
|
|
|
|
Inhibitor of mdm2-p53 interaction
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: plyss
|
|
|
Chain:
A
(92 residues)
|
|
|
|
|
|
Inhibitor of mdm2-p53 interaction
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: plyss
|
|
|
Chain:
A
(92 residues)
|
|
|
|
|
|
Inhibitor of mdm2-p53 interaction
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: plyss
|
|
|
Chain:
A
(92 residues)
|
|
|
|
|
|
Inhibitor of mdm2-p53 interaction
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: plyss
|
|
|
Chains:
A, B
(93 residues)
|
|
|
|
|
|
Inhibitor of mdm2-p53 interaction
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: plyss
|
|
|
Chain:
A
(92 residues)
|
|
|
|
|
|
Inhibitor of mdm2-p53 interaction
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: plyss
|
|
|
Chain:
A
(92 residues)
|
|
|
|
|
|
Avr1d:gmpub13 u-box
|
|
|
Source: Phytophthora sojae (strain p6497). Soybean stem and root rot agent. Organism_taxid: 1094619. Strain: p6497. Gene: avh6, avh6-1, avr1d. Expressed in: escherichia coli. Expression_system_taxid: 562. Glycine soja. Wild soybean.
|
|
|
Chain:
B
(73 residues)
|
|
|
|
|
|
Nse1-nse3-nse4 complex
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Gene: nsmce1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: xelaev_18029664mg. Gene: nsmce4a.L, loc100158435, nsmce4a. Expression_system_taxid: 562
|
|
|
Chain:
A
(231 residues)
|
|
|
|
|
|
Crystal structure of vim1 phd finger.
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: orth2, vim1, at1g57820, f12k22.14. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(62 residues)
|
|
|
|
|
|
Cryo-em structure of the activated human minor spliceosome (minor bact complex)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
9, M
(409 residues)
|
|
|
|
Bound ligand:
|
Het Group GTP
is 96.88% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Structural insight into brca1-bard1 complex recruitment to damaged chromatin
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Xenopus laevis. African clawed frog. Organism_taxid: 8355. Gene: xelaev_18002543mg. Gene: h2ac14.L, h2ac14, hist1h2aj, loc494591, xelaev_18003602mg.
|
|
|
Chain:
K
(334 residues)
|
|
|
|
|
|
Crystal structure of human uhrf1 ttd in complex with 5-amino-2,4- dimethylpyridine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(155 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z45705015
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1079512010
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1401276297
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1696844792
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z453319206
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1980894300
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z285642082
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1328968520
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z29077827
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z32327641
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1430613393
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z328695024
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z741055844
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z32367954
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z235449082
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z256709358
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z793778804
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z32400357
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1359419878
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1407673036
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z192955056
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z285782452
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z291279160
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1374778753
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1954800564
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z425387594
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z319545618
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1367324110
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z274575916
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1578665941
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z271004858
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1354416068
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z165170770
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z57478994
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z198194394
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1530301542
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z126932614
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1741966151
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z56978034
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1492796719
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z763030030
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z111782404
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1217960891
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z56827661
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z45617795
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z198194396
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1929757385
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z31478538
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z220996120
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z52314092
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1568344634
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z373768900
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1275599911
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1251207602
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z31432226
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z57450788
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z106579662
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z30620520
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1545312521
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z2072621991
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z383202616
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1614545742
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z404993336
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z133729708
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z44592329
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1245793018
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z730649594
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1003146540
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z1266933824
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z30820160
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z993967070
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21 in complex with z275165822
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of trim21, ground state
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Cryo-em structure of mda5-dsrna in complex with trim65 pspry domain (monomer)
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Gene: ifih1, mda5, rh116. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: trim65. Expression_system_taxid: 562
|
|
|
Chain:
B
(180 residues)
|
|
|
|
|
|
Cryo-em structure of rig-i:dsrna in complex with riplet pryspry domain (monomer)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ddx58. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Gene: rnf135, l13. Expression_system_taxid: 562
|
|
|
Chain:
B
(171 residues)
|
|
|
|
|
|
Cryo-em structure of mda5-dsrna filament in complex with trim65 pspry domain (trimer)
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Gene: ifih1, mda5, rh116. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: trim65. Expression_system_taxid: 562
|
|
|
Chains:
B, D, F
(180 residues)
|
|
|
|
|
|
Cryo-em structure of rig-i:dsrna filament in complex with riplet pryspry domain (trimer)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ddx58. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf135, l13. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
B, D, F
(169 residues)
|
|
|
|
|
|
Crystal structure of trim65 pspry domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim65. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, C, B
(190 residues)
|
|
|
|
|
|
Cryo-em structure of the brca1-ubch5c/bard1 e3-e2 module bound to a nucleosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, ube2d3, ubc5c, ubch5c. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: bard1. Gene: h2ac18, h2afo, hist2h2aa, hist2h2aa3, h2ac19, hist2h2aa4. Gene: h2bc12, h2bft, hirip1, hist1h2bk.
|
|
|
Chains:
A, B
(253 residues)
|
|
|
|
|
|
Solution nmr structure of the coiled-coil brca1-palb2 heterodimer
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Cell_line: bl21. Gene: brca1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: palb2. Expressed in: escherichia coli bl21.
|
|
|
Chain:
A
(60 residues)
|
|
|
|
|
|
Crystal structure of human mdm2 in complex with d-peptide inhibitor (dpmi-omega)
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, C
(85 residues)
|
|
|
|
|
|
Structure of traf5 and traf6 ring hetero dimer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf5, rnf84. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: traf6, rnf85. Expression_system_taxid: 562
|
|
|
Chains:
B, D
(107 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with brca1-bard1-ubch5c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
M, N
(94 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle ubiquitylated at histone h2a lys13 and lys15 in complex with bard1 (residues 415- 777)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
N
(335 residues)
|
|
|
|
|
|
Crystal structure of rbr e3 ligase rnf216 with ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf216, triad3, ubce7ip1, zin. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(173 residues)
|
|
|
|
|
|
Crystal structure of rbr e3 ligase rnf216 in complex with k63-linked di-ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf216, triad3, ubce7ip1, zin. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(120 residues)
|
|
|
|
|
|
Crystal structure of phosphorylated rbr e3 ligase rnf216 in complex with k63-linked di-ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf216, triad3, ubce7ip1, zin. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ubc. Expression_system_taxid: 469008
|
|
|
Chain:
A
(116 residues)
|
|
|
|
|
|
Structure of yeast ubr1 in complex with ubc2 and n-degron
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c.
|
|
|
Chain:
A
(1737 residues)
|
|
|
|
|
|
Structure of yeast ubr1 in complex with ubc2 and monoubiquitinated n- degron
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ubr1, ptr1, ygr184c, g7168. Expressed in: saccharomyces cerevisiae s288c. Expression_system_taxid: 559292. Homo sapiens.
|
|
|
Chain:
A
(1731 residues)
|
|
|
|
|
|
Hdm2 in complex with compound 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(89 residues)
|
|
|
|
|
|
Hdm2 in complex with compound 56
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(96 residues)
|
|
|
|
|
|
Hdm2 in complex with compound 62
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(96 residues)
|
|
|
|
|
|
Hdm2 in complex with compound 63
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(96 residues)
|
|
|
|
|
|
First-in-class small molecule inhibitors of polycomb repressive complex 1 (prc1) ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf2, bap1, ding, hipi3, ring1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: bmi1, pcgf4, rnf51. Expression_system_taxid: 562
|
|
|
Chain:
A
(100 residues)
|
|
|
|
|
|
Structure of the bir1 domain of ciap2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc3, api2, mihc, rnf49. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
D, E
(74 residues)
|
|
|
|
|
|
Catalytic module of yeast chelator-gid sr4 e3 ubiquitin ligase
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rmd5, gid2, ydr255c, yd9320a.05c. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: fyv10, gid9, yil097w.
|
|
|
Chains:
b, i
(340 residues)
|
|
|
|
|
|
X-ray structure of hdm2/cmr19 at 1.45a: discovery, x-ray structure and cpp-conjugation enabled uptake of p53/mdm2 macrocyclic peptide inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B, C
(86 residues)
|
|
|
|
|
|
First sh3 domain of posh (plenty of sh3 domains protein)
|
|
|
Source: Homo sapiens
|
|
|
Chain:
A
(61 residues)
|
|
|
|
|
|
Fourth sh3 domain of posh (plenty of sh3 domains protein)
|
|
|
Source: Homo sapiens
|
|
|
Chain:
A
(63 residues)
|
|
|
|
|
|
Trim3 filamin domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim3, berp, rnf22, rnf97. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(104 residues)
|
|
|
|
|
|
Mouse rnf213:ube2l3 transthiolation intermediate, chemically stabilized
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rnf213, mystr. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(4426 residues)
|
|
|
|
|
|
Mouse rnf213, with mixed nucleotides bound
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: rnf213, mystr. Expressed in: trichoplusia ni. Expression_system_taxid: 7111
|
|
|
Chain:
A
(4426 residues)
|
|
|
|
|
|
E2 ube2k covalently linked to donor ub, acceptor di-ub, and ring e3 primed for k48-linked ub chain synthesis
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf38. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ube2k, hip2, lig. Gene: ubb.
|
|
|
Chain:
A
(68 residues)
|
|
|
|
|
|
Cryo-em structure of the ddb1-dcaf1-cul4a-rbx1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ddb1, xap1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: dcaf1, kiaa0800, rip, vprbp. Gene: cul4a. Gene: rbx1, rnf75, roc1.
|
|
|
Chains:
D, H, L, P
(72 residues)
|
|
|
|
|
|
Structure of neddylated cul5 c-terminal region-rbx2-arih2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul5, vacm1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: arih2, ari2, triad1, ht005. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
|
|
|
Chain:
R
(86 residues)
|
|
|
|
|
|
Pol ii-csb-crl4csa-uvssa-spt6-paf (structure 4)
|
|
|
Source: Sus scrofa. Organism_taxid: 9823. Pig. Homo sapiens. Human. Organism_taxid: 9606. Gene: supt6h, kiaa0162, spt6h. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chain:
f
(21 residues)
|
|
|
|
|
|
Pol ii-csb-crl4csa-uvssa-spt6-paf (structure 5)
|
|
|
Source: Sus scrofa. Pig. Organism_taxid: 9823. Homo sapiens. Human. Organism_taxid: 9606. Gene: supt6h, kiaa0162, spt6h. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chain:
f
(21 residues)
|
|
|
|
|
|
E3 ring ligase binding domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia phage ecszw-2. Expression_system_taxid: 2419741. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(174 residues)
|
|
|
|
|
|
E3 ring ligase binding domain with peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf187. Expressed in: homo sapiens. Expression_system_taxid: 9606
|
|
|
Chains:
A, B, C, D
(171 residues)
|
|
|
|
|
|
Solution nmr structure of arginine to cysteine mutant of arkadia ring domain.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf111. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(69 residues)
|
|
|
|
|
|
Cryoem structure of the smc5/6-holocomplex (composite structure)
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: smc5, yol034w. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: smc6, rhc18, ylr383w, l3502.2.
|
|
|
Chain:
D
(326 residues)
|
|
|
|
|
|
Crystal structure of hdm2 in complex with caylin-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(91 residues)
|
|
|
|
|
|
Apo structure of bir2 domain of birc2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(79 residues)
|
|
|
|
|
|
Crystal structure of nhl domain of trim2 (full c-terminal)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim2, kiaa0517, rnf86. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chains:
A, B, C, D
(278 residues)
|
|
|
|
|
|
Crystal structure of nhl domain of trim3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim3, berp, rnf22, rnf97. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chain:
A
(276 residues)
|
|
|
|
|
|
Crystal structure of nhl domain of trim71
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim71, lin41. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chains:
A, B
(279 residues)
|
|
|
|
|
|
Crystal structure of b30.2 pryspry domain of mid1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mid1, fxy, rnf59, trim18, xprf. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chains:
A, B, C, D
(164 residues)
|
|
|
|
|
|
Crystal structure of b30.2 pryspry domain of mid2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mid2, fxy2, rnf60, trim1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chain:
A
(171 residues)
|
|
|
|
|
|
Crystal structure of b30.2 pryspry domain of trim11
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim11, rnf92. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chains:
A, B
(184 residues)
|
|
|
|
|
|
Crystal structure of b30.2 pryspry domain of trim15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim15. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chain:
A
(172 residues)
|
|
|
|
|
|
Crystal structure of b30.2 pryspry domain of trim16
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim16, ebbp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chain:
A
(193 residues)
|
|
|
|
|
|
Crystal structure of b30.2 pryspry domain of trim36
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: -r3-prare2.
|
|
|
Chains:
A, B, C, D
(206 residues)
|
|
|
|
|
|
Structural organization of a late activated human spliceosome (baqr, core region)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Synthetic: yes. Unidentified adenovirus. Organism_taxid: 10535. Organism_taxid: 9606
|
|
|
Chains:
Z, u
(95 residues)
|
|
|
|
|
|
Crystal structure of the ubark2c fusion protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc, rnf165. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(150 residues)
|
|
|
|
|
|
Crystal structure of the ubark2c-ubch5b~ub complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc, rnf165. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ubc. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expression_system_taxid: 469008
|
|
|
Chain:
A
(147 residues)
|
|
|
|
|
|
Ccbl tkb domain in complex with pzap70 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(304 residues)
|
|
|
|
|
|
Structure of the peroxisomal retro-translocon formed by a heterotrimeric ubiquitin ligase complex
|
|
|
Source: Thermothelomyces thermophilus atcc 42464. Organism_taxid: 573729. Strain: atcc 42464 / bcrc 31852 / dsm 1799. Gene: mycth_2053677. Expressed in: komagataella pastoris. Expression_system_taxid: 4922. Gene: mycth_2294472. Gene: mycth_2294231. Synthetic construct.
|
|
|
Chain:
C
(317 residues)
|
|
|
|
|
|
Crystal structure of stub1 with a macrocyclic peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(127 residues)
|
|
|
|
|
|
Crystal structure of human birc2 bir3 domain in complex with histone h3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(90 residues)
|
|
|
|
|
|
Crystal structure of human birc2 bir3 domain in complex with inhibitor lcl-161
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(87 residues)
|
|
|
|
|
|
Atp and DNA bound smc5/6 core complex
|
|
|
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Saccharomyces cerevisiae w303. Organism_taxid: 580240. Gene: pacbioseq_locus3862. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: smc6, rhc18, ylr383w, l3502.2.
|
|
|
Chain:
C
(310 residues)
|
|
|
|
|
|
Human gator2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mios. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek-293t. Expression_system_atcc_number: crl-3216. Gene: wdr24, c16orf21, jfp7.
|
|
|
Chain:
C
(578 residues)
|
|
|
|
|
|
Rad6-bre1 complex
|
|
|
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rad6, ubc2, ygl058w. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: bre1, ydl074c.
|
|
|
Chains:
V, U
(160 residues)
|
|
|
|
|
|
Rad6(p43l)-bre1 complex
|
|
|
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rad6, ubc2, ygl058w. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: bre1, ydl074c.
|
|
|
Chains:
V, U
(160 residues)
|
|
|
|
|
|
Crystal structure of ipah1.4 lrr domain bound to hoil-1l ubl domain.
|
|
|
Source: Shigella flexneri 5a str. M90t. Organism_taxid: 1086030. Strain: m90t. Gene: ipah1.4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
B, A
(236 residues)
|
|
|
|
|
|
Crystal structure of hoip ring1 domain bound to ipah1.4 lrr domain
|
|
|
Source: Shigella flexneri serotype 5a (strain m90t). Organism_taxid: 1086030. Strain: m90t. Gene: ipah1.4, s0283, pwr501_0283. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, B
(235 residues)
|
|
|
|
|
|
Crystal structure of lrr domain from shigella flexneri ipah1.4
|
|
|
Source: Shigella flexneri 5a str. M90t. Organism_taxid: 1086030. Strain: m90t. Gene: ipah1.4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(236 residues)
|
|
|
|
|
|
Cryo-em structure of ultraviolet-b activated uvr8 in complex with cop1
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: cop1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Gene: uvr8. Expressed in: escherichia coli bl21(de3).
|
|
|
Chain:
A
(304 residues)
|
|
|
|
|
|
Trim7 in complex with c-terminal peptide of 2c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Coxsackievirus. Organism_taxid: 12066
|
|
|
Chain:
A
(173 residues)
|
|
|
|
|
|
Trim7 in complex with c-terminal peptide of 2c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Coxsackievirus. Organism_taxid: 12066
|
|
|
Chains:
B, C, E
(169 residues)
|
|
|
|
|
|
Trim7 in complex with c-terminal peptide of 2c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Coxsackievirus. Organism_taxid: 12066
|
|
|
Chains:
F, C, B
(169 residues)
|
|
|
|
|
|
The cryo-em structure of human prE-C -I complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Synthetic: yes. Unidentified adenovirus. Organism_taxid: 10535. Organism_taxid: 9606
|
|
|
Chains:
q, r, s, t
(132 residues)
|
|
|
|
|
|
The cryo-em structure of human prE-C -Ii complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Synthetic: yes. Unidentified adenovirus. Organism_taxid: 10535. Organism_taxid: 9606
|
|
|
Chains:
q, r, s, t
(132 residues)
|
|
|
|
|
|
Crystal structure of the k. Lactis bre1 rbd in complex with rad6, crystal form i
|
|
|
Source: Kluyveromyces lactis nrrl y-1140. Organism_taxid: 284590. Strain: nrrl y-1140. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: bre1. Expression_system_taxid: 562
|
|
|
Chains:
C, D, E, F
(159 residues)
|
|
|
|
|
|
Crystal structure of the k. Lactis bre1 rbd in complex with rad6, crystal form ii
|
|
|
Source: Kluyveromyces lactis nrrl y-1140. Organism_taxid: 284590. Strain: nrrl y-1140. Gene: ubc2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: bre1. Expression_system_taxid: 562
|
|
|
Chains:
C, D, E, F
(157 residues)
|
|
|
|
|
|
Crystal structure of gsdmb in complex with ipah7.8
|
|
|
Source: Shigella flexneri. Organism_taxid: 623. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: gsdmb, gsdml, pp4052, pro2521. Expression_system_taxid: 562
|
|
|
Chain:
A
(233 residues)
|
|
|
|
|
|
Crystal structure of ubr bof from prt6
|
|
|
Source: Oryza sativa subsp. Japonica. Rice. Organism_taxid: 39947. Gene: os01g0148000, osnpb_010148000. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(68 residues)
|
|
|
|
|
|
Crystal structure of ubr bof from prt6 (rdg ph5.5)
|
|
|
Source: Synthetic: yes. Oryza sativa. Organism_taxid: 4530. Oryza sativa subsp. Japonica. Rice. Organism_taxid: 39947. Gene: os01g0148000, osnpb_010148000. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(70 residues)
|
|
|
|
|
|
Crystal structure of ubr box from prt6 (rdg ph 8.5)
|
|
|
Source: Synthetic: yes. Oryza sativa. Organism_taxid: 4530. Oryza sativa subsp. Japonica. Rice. Organism_taxid: 39947. Gene: os01g0148000, osnpb_010148000. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(70 residues)
|
|
|
|
|
|
Crystal structure of ubr bof from prt6 (rsg)
|
|
|
Source: Synthetic: yes. Oryza sativa. Organism_taxid: 4530. Oryza sativa subsp. Japonica. Rice. Organism_taxid: 39947. Gene: os01g0148000, osnpb_010148000. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(70 residues)
|
|
|
|
|
|
Trim7 in complex with c-terminal peptide of nsp5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Severe acute respiratory syndrome coronavirus 2.
|
|
|
Chain:
A
(169 residues)
|
|
|
|
|
|
Trim7 in complex with c-terminal peptide of nsp12
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Severe acute respiratory syndrome coronavirus 2.
|
|
|
Chain:
A
(170 residues)
|
|
|
|
|
|
Trim7 in complex with c-terminal peptide of nsp8
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Severe acute respiratory syndrome coronavirus 2.
|
|
|
Chain:
A
(170 residues)
|
|
|
|
|
|
Crystal structure of oscie1-ubox and osubc8 complex
|
|
|
Source: Oryza sativa japonica group. Japanese rice. Organism_taxid: 39947. Gene: osj_21490. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: pub12, os06g0102700, loc_os06g01304, osjnba0075g19.19-1. Expression_system_taxid: 562
|
|
|
Chains:
C, D
(77 residues)
|
|
|
|
|
|
Nmr strucutre of chimeric protein for model of phd-stella complex
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: uhrf1, dppa3. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(126 residues)
|
|
|
|
|
|
Crystal structure of trim72
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim72, mg53. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A
(388 residues)
|
|
|
|
|
|
Trim e3 ubiquitin ligase
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim72, mg53. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(382 residues)
|
|
|
|
|
|
Apo-atprt6 ubr box
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt6, cer3, ged1, at5g02310/at5g02300, t1e22.70/t1e22.60. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(70 residues)
|
|
|
|
|
|
Rrgsgg-atprt6 ubr box
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt6, cer3, ged1, at5g02310/at5g02300, t1e22.70/t1e22.60. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(76 residues)
|
|
|
|
|
|
Rlgsgg-atprt6 ubr box (highest resolution)
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt6, cer3, ged1, at5g02310/at5g02300, t1e22.70/t1e22.60. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(73 residues)
|
|
|
|
|
|
Rsgsgg-atprt6 ubr box
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt6, cer3, ged1, at5g02310/at5g02300, t1e22.70/t1e22.60. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(72 residues)
|
|
|
|
|
|
Trim e3 ubiquitin ligase wt
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim72, mg53. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(382 residues)
|
|
|
|
|
|
Trim e3 ubiquitin ligase
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim72, mg53. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D
(453 residues)
|
|
|
|
|
|
Trim e3 ubiquitin ligase
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim72, mg53. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(386 residues)
|
|
|
|
|
|
Trim e3 ubiquitin ligase
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim72, mg53. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(382 residues)
|
|
|
|
|
|
Trim e3 ubiquitin ligase
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim72, mg53. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D
(382 residues)
|
|
|
|
|
|
Crystal structure of trim7 bound to 2c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, C, B
(181 residues)
|
|
|
|
|
|
Crystal structure of trim7 bound to gn1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(177 residues)
|
|
|
|
|
|
Crystal structure of trim7 bound to raco-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(180 residues)
|
|
|
|
|
|
Structure of human mg53 homo-dimer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim72, mg53. Expressed in: escherichia coli b. Expression_system_taxid: 37762
|
|
|
Chains:
A, B
(343 residues)
|
|
|
|
|
|
Rrgsgg-atprt6 ubr box (i222)
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt6, cer3, ged1, at5g02310/at5g02300, t1e22.70/t1e22.60. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(73 residues)
|
|
|
|
|
|
Rrgsgg-atprt6 ubr box (p32)
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt6, cer3, ged1, at5g02310/at5g02300, t1e22.70/t1e22.60. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, D, E, F, G, H, C
(76 residues)
|
|
|
|
|
|
Rlgsgg-atprt6 ubr box (c121)
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt6, cer3, ged1, at5g02310/at5g02300, t1e22.70/t1e22.60. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(72 residues)
|
|
|
|
|
|
Rlgsgg-atprt6 ubr box (i222)
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt6, cer3, ged1, at5g02310/at5g02300, t1e22.70/t1e22.60. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(73 residues)
|
|
|
|
|
|
Rlgsgg-atprt6 ubr box (p4332)
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt6, cer3, ged1, at5g02310/at5g02300, t1e22.70/t1e22.60. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(77 residues)
|
|
|
|
|
|
The crystal structure of ipah1.4 lrr domain
|
|
|
Source: Shigella flexneri 5a. Organism_taxid: 1086030. Strain: m90t. Gene: ipah1.4, s0283, pwr501_0283. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(234 residues)
|
|
|
|
|
|
The crystal structure of ipah2.5 lrr domain
|
|
|
Source: Shigella flexneri 5a. Organism_taxid: 1086030. Strain: m90t. Gene: ipah2.5, s0056, ekn05_023760, pwr501_0056. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(237 residues)
|
|
|
|
|
|
Cryo-em structure of nse1/3/4
|
|
|
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Strain: s288c. Gene: nse4. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: nse1. Gene: nse3. Expression_system_taxid: 562
|
|
|
Chain:
B
(322 residues)
|
|
|
|
|
|
Crystal structure of pirh2 bound to poly-ala peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rchy1, arnip, chimp, pirh2, rnf199, znf363. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(188 residues)
|
|
|
|
|
|
Notothenia coriiceps traf4
|
|
|
Source: Notothenia coriiceps. Black rockcod. Organism_taxid: 8208. Gene: traf4. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(164 residues)
|
|
|
|
|
|
Cryo-em structure of 8-subunit smc5/6
|
|
|
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Strain: s288c. Gene: smc5. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: smc6. Gene: nse2. Gene: kre29.
|
|
|
Chain:
F
(322 residues)
|
|
|
|
|
|
Crystal structure of the kap1 tripartite motif in complex with the znf93 krab domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim28, kap1, rnf96, tif1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: znf93, znf505. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(433 residues)
|
|
|
|
|
|
Structure of crl7fbxw8 reveals coupling with cul1-rbx1/roc1 for multi- cullin-ring e3-catalyzed ubiquitin ligation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul7, kiaa0076. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: fbxw8, fbw6, fbw8, fbx29, fbxo29, fbxw6. Gene: rbx1, rnf75, roc1. Gene: skp1, emc19, ocp2, skp1a, tceb1l.
|
|
|
Chain:
R
(86 residues)
|
|
|
|
|
|
Cand1-cul1-rbx1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
R
(86 residues)
|
|
|
|
|
|
Cand1-scf-skp2 cand1 engaged scf rocked
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
R
(86 residues)
|
|
|
|
|
|
Cand1-scf-skp2 (skp1deldel) cand1 engaged scf rocked
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
R
(86 residues)
|
|
|
|
|
|
Cand1-scf-skp2 cand1 rolling-2 scf engaged
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: rbx1, rnf75, roc1. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3).
|
|
|
Chain:
R
(11 residues)
|
|
|
|
|
|
Cand1 delhairpin-scf-skp2 cand1 partly engaged scf partly rocked
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
R
(86 residues)
|
|
|
|
|
|
Crystal structure of trim33 phd-bromodomain isoform b in complex with h3k10ac histone peptide.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim33, kiaa1113, rfg7, tif1g. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: peptide contains an extra lysine on thE C-terminus when compared with the wild-type [artkqtark(ac)]
|
|
|
Chain:
A
(176 residues)
|
|
|
|
|
|
Structure of trim2 ring domain in complex with ube2d1~ub conjugate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim2, kiaa0517, rnf86. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ube2d1, sft, ubc5a, ubch5, ubch5a. Gene: ubc. Expression_system_taxid: 562
|
|
|
Chains:
D, G, J, A
(85 residues)
|
|
|
|
|
|
Hops tethering complex from yeast
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: atcc 204508 / s288c. Gene: pep5, end1, vam1, vpl9, vps11, vpt11, ymr231w, ym9959.13. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: vps16, vam9, vpt16, ypl045w. Gene: pep3, vam8, vps18, vpt18, ylr148w, l9634.2.
|
|
|
Chain:
A
(954 residues)
|
|
|
|
|
|
Ring domain of human trim2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim2, kiaa0517, rnf86. Expressed in: escherichia coli b. Expression_system_taxid: 37762.
|
|
|
Chains:
A, B, C
(75 residues)
|
|
|
|
|
|
X-ray structure of trim21 ring e3 ligase in complex with e2 enzyme ube2w
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2w, ubc16. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: trim21, rnf81, ro52, ssa1. Expression_system_taxid: 469008
|
|
|
Chains:
C, D
(82 residues)
|
|
|
|
|
|
Trim7 pryspry in complex with a 2bc peptide tiealfq
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41. Synthetic: yes. Enterovirus a71.
|
|
|
Chain:
A
(173 residues)
|
|
|
|
|
|
Trim7 pryspry in complex with a mnv1-ns6 peptide lealefq
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41. Synthetic: yes. Murine norovirus 1.
|
|
|
Chains:
A, B
(171 residues)
|
|
|
|
|
|
Trim7 pryspry in complex with a mnv1-ns3 peptide hddfglq
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7, gnip, rnf90. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41. Synthetic: yes. Murine norovirus 1.
|
|
|
Chains:
A, C
(173 residues)
|
|
|
|
|
|
Structure of hmdm2 in complex with nutlin-3a-aa
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606
|
|
|
Chain:
A
(87 residues)
|
|
|
|
|
|
Coiled-coil domain of human trim3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim3, berp, rnf22, rnf97. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C
(155 residues)
|
|
|
|
|
|
Complex of human trim2 ring domain, ubch5c, and ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d3, ubc5c, ubch5c. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: trim2, kiaa0517, rnf86. Gene: ubc. Expression_system_taxid: 469008
|
|
|
Chains:
C, D
(83 residues)
|
|
|
|
|
|
Structure of rip2k dimer bound to the xiap bir2 domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ripk2, cardiak, rick, rip2, unq277/pro314/pro34092. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
|
|
|
Chain:
C
(76 residues)
|
|
|
|
|
|
C(n)rl4csa-uvssa-e2-ubiquitin complex.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: nedd8. Gene: rbx1, rnf75, roc1. Expressed in: trichoplusia ni.
|
|
|
Chain:
R
(79 residues)
|
|
|
|
|
|
Crl4csa-e2-ub (state 2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: nedd8. Gene: rbx1, rnf75, roc1. Expressed in: trichoplusia ni.
|
|
|
Chain:
R
(79 residues)
|
|
|
|
|
|
Crystal structure of the e3 module from ubr4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(346 residues)
|
|
|
|
|
|
Crystal structure of trim33 alpha phd-bromo domain in complex with 8
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim33, kiaa1113, rfg7, tif1g. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(194 residues)
|
|
|
|
|
|
Crystal structure of trim33 alpha phd-bromo domain in complex with 10
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim33, kiaa1113, rfg7, tif1g. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(184 residues)
|
|
|
|
|
|
Crystal structure of trim33 alpha phd-bromo domain in complex with 9
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim33, kiaa1113, rfg7, tif1g. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(190 residues)
|
|
|
|
|
|
Human mdm2-5s rnp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932.
|
|
|
Chain:
F
(42 residues)
|
|
|
|
|
|
Crystal structure of a complex between the e2 conjugating enzyme ube2a and the e3 ligase module from ubr4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ube2a. Expression_system_taxid: 562
|
|
|
Chain:
A
(354 residues)
|
|
|
|
|
|
Cand1 b-hairpin++-scf-skp2 cand1 rolling scf engaged
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: rbx1, rnf75, roc1. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3).
|
|
|
Chain:
R
(11 residues)
|
|
|
|
|
|
Cand1 b-hairpin++-scf-skp2 cand1 partly engaged scf partly rocked
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
R
(86 residues)
|
|
|
|
|
|
X-ray structure of the wd40 domain of hops subunit vps11 from yeast
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: atcc 204508 / s288c. Gene: pep5, end1, vam1, vpl9, vps11, vpt11, ymr231w, ym9959.13. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(330 residues)
|
|
|
|
|
|
Structure of ciap1 with bccov
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(92 residues)
|
|
|
|
|
|
Structure of ciap1, btk and bccov
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: btk, agmx1, atk, bpk. Expressed in: spodoptera aff. Frugiperda 2 rz-2014. Expression_system_taxid: 1491790. Gene: birc2, api1, mihb, rnf48. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
D
(91 residues)
|
|
|
|
|
|
Inhibitor-3:pp1 reconstituted complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ppp1ca, ppp1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ppp1r11, hcgv, tcte5. Expression_system_taxid: 562
|
|
|
Chains:
C, D
(28 residues)
|
|
|
|
|
|
Inhibitor-3:pp1 coexpressed complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ppp1ca, ppp1a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: expi293. Gene: ppp1r11, hcgv, tcte5. Expression_system_cell_line: expi293
|
|
|
Chains:
D, B
(23 residues)
|
|
|
|
|
|
Rnf216/e2-ub/ub transthiolation complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf216, triad3, ubce7ip1, zin. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ube2l3, ubce7, ubch7. Gene: ubc. Expression_system_taxid: 469008
|
|
|
Chain:
A
(255 residues)
|
|
|
|
|
|
Cryoem structure of gsdmb in complex with shigella ipah7.8
|
|
|
Source: Shigella flexneri. Organism_taxid: 623. Gene: ipah7.8, cp0078, pwr501_0084, sflp133. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: gsdmb, gsdml, pp4052, pro2521.
|
|
|
Chain:
B
(243 residues)
|
|
|
|
|
|
Crystal structure of the stub1 tpr domain in complex with h317, a helicon polypeptide
|
|
|
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(129 residues)
|
|
|
|
|
|
Crystal structure of the stub1 tpr domain in complex with h318, a helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(132 residues)
|
|
|
|
|
|
Crystal structure of beta-catenin and the mdm2 p53-binding domain in complex with h332, a helicon polypeptide
|
|
|
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human. Organism_taxid: 9606. Gene: ctnnb1, ctnnb, ok/sw-cl.35, pro2286. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
B
(86 residues)
|
|
|
|
|
|
Crystal structure of beta-catenin and the mdm2 p53-binding domain in complex with h333, a helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ctnnb1, ctnnb, ok/sw-cl.35, pro2286. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: mdm2. Synthetic: yes. Synthetic construct.
|
|
|
Chain:
B
(85 residues)
|
|
|
|
|
|
Crystal structure of beta-catenin and the mdm2 p53-binding domain in complex with h329, a helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ctnnb1, ctnnb, ok/sw-cl.35, pro2286. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: mdm2. Synthetic: yes. Synthetic construct.
|
|
|
Chain:
B
(86 residues)
|
|
|
|
|
|
Crystal structure of beta-catenin and the mdm2 p53-binding domain in complex with h330, a helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ctnnb1, ctnnb, ok/sw-cl.35, pro2286. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: mdm2. Synthetic: yes. Synthetic construct.
|
|
|
Chain:
B
(86 residues)
|
|
|
|
|
|
Structure of the mdm2 p53 binding domain in complex with h101, an all- d helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(86 residues)
|
|
|
|
|
|
Structure of the mdm2 p53 binding domain in complex with h102, an all- d helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(87 residues)
|
|
|
|
|
|
Structure of the mdm2 p53 binding domain in complex with h103, an all- d helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(95 residues)
|
|
|
|
|
|
Structure of the mdm2 p53 binding domain in complex with h103, an all- d helicon polypeptide, alternativE C-terminus
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: synthetic construct. Expression_system_taxid: 32630. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(95 residues)
|
|
|
|
|
|
Structure of the stub1 tpr domain in complex with h201, an all-d helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(132 residues)
|
|
|
|
|
|
Structure of the stub1 tpr domain in complex with h202, an all-d helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B, C
(133 residues)
|
|
|
|
|
|
Structure of the stub1 tpr domain in complex with h203, an all-d helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(134 residues)
|
|
|
|
|
|
Structure of the stub1 tpr domain in complex with h204, an all-d helicon polypeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(129 residues)
|
|
|
|
|
|
Crystal structure of the coiled-coil domain of trim56
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim56. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D
(78 residues)
|
|
|
|
|
|
Crystal structure of the human chip-tpr domain in complex with a 10mer acetylated tau peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
B, A
(128 residues)
|
|
|
|
|
|
Structure of znrf3 ecd bound to peptide mk1-3.6.10
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: znrf3, kiaa1133, rnf203. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(155 residues)
|
|
|
|
|
|
Cryo-em structure of riplet:rig-i:dsrna complex (end-end)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ddx58. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf135, l13. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
B, D
(178 residues)
|
|
|
|
|
|
Cryo-em structure of riplet:rig-i:dsrna complex (end-semi-closed end)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ddx58. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf135, l13. Expression_system_taxid: 562
|
|
|
Chains:
B, D
(178 residues)
|
|
|
|
|
|
Cryo-em structure of riplet:rig-i:dsrna complex (end-inter)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ddx58. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf135, l13. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
B, D
(178 residues)
|
|
|
|
|
|
Structure of rnf125 in complex with ubch5b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf125. Expression_system_taxid: 562
|
|
|
Chain:
B
(93 residues)
|
|
|
|
|
|
Structure of rnf125 in complex with a ubch5b~ub conjugate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rnf125. Expression_system_taxid: 562
|
|
|
Chain:
B
(93 residues)
|
|
|
|
|
|
Crystal structure of the human chip-tpr domain in complex with a 6mer acetylated tau peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
B, A
(128 residues)
|
|
|
|
|
|
Co-crystal structure of cbl-b in complex with n-aryl isoindolin-1-one inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb, rnf56, nbla00127. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(376 residues)
|
|
|
|
|
|
142d6 bound to bir3-xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(93 residues)
|
|
|
|
|
|
Cryo-em structure of the kbtbd2-cul3-rbx1 dimeric complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 7108
|
|
|
Chains:
E, D
(89 residues)
|
|
|
|
|
|
Cryo-em structure of prc1 bound to h2ak119-ubch5b-ub nucleosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: loc102839401, loc102825049, loc102826576. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h2ac4, h2afm, hist1h2ab, h2ac8, h2afa, hist1h2ae. Gene: h2bc12, h2bft, hirip1, hist1h2bk. Gene: commd3.
|
|
|
Chain:
N
(101 residues)
|
|
|
|
|
|
Cryo-em structure of brca1/bard1 bound to h2ak127-ubch5c-ub nucleosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: calmac_locus17614. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: dana\gf27365, dana_gf27365, gf27365. Gene: h2ac12, hist1h2ah. Gene: brca1, rnf53.
|
|
|
Chains:
K, M
(92 residues)
|
|
|
|
|
|
Crystal structure of ipah7.8-lrr and gsdmb isoform-4 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsdmb, gsdml, pp4052, pro2521. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Shigella flexneri. Organism_taxid: 623. Gene: ipah7.8, cp0078, pwr501_0084, sflp133.
|
|
|
Chains:
B, D
(236 residues)
|
|
|
|
|
|
Crystal structure of ipah7.8-lrr and gsdmb isoform-1 complex
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Shigella flexneri. Organism_taxid: 623. Gene: ipah7.8, cp0078, pwr501_0084, sflp133. Expression_system_taxid: 469008
|
|
|
Chain:
B
(236 residues)
|
|
|
|
|
|
Bre1-nucleosome complex (model i)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h2bc11, h2bfr, hist1h2bj. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chains:
K, L
(72 residues)
|
|
|
|
|
|
Bre1-nucleosome complex (model ii)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h2ac11, h2afp, hist1h2ag, h2ac13, h2afc, hist1h2ai, h2ac15, h2afd, hist1h2ak, h2ac16, h2afi, hist1h2al, h2ac17, h2afn, hist1h2am. Gene: h2bc11, h2bfr, hist1h2bj.
|
|
|
Chains:
K, L
(72 residues)
|
|
|
|
|
|
Cryo-em structure of the kbtbd2-cul3-rbx1 tetrameric complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 7108
|
|
|
Chains:
D, K, L, E
(89 residues)
|
|
|
|
|
|
Cryo-em structure of the kbtbd2-cul3-rbx1 hexameric complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul3, kiaa0617. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 7108
|
|
|
Chains:
R, Q, E, D, L, K
(89 residues)
|
|
|
|
|
|
Cryo-em structure of the kbtbd2-cul3-rbx1 octameric complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul3, kiaa0617. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 7108
|
|
|
Chains:
E, D, L, K, R, Q, W, X
(89 residues)
|
|
|
|
|
|
Cryo-em structure of the kbtbd2-cul3-rbx1-p85a dimeric complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rbx1, rnf75, roc1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: kbtbd2, bklhd1, kiaa1489, cgi-73. Gene: pik3r1, grb1. Gene: cul3, kiaa0617.
|
|
|
Chains:
E, D
(89 residues)
|
|
|
|
|
|
Cryo-em structure of the kbtbd2-cul3-rbx1-p85a tetrameric complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul3, kiaa0617. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Gene: kbtbd2, bklhd1, kiaa1489, cgi-73. Gene: pik3r1, grb1.
|
|
|
Chains:
E, D, R, Q
(89 residues)
|
|
|
|
|
|
Cryo-em structure of the kbtbd2-crl3~n8-csn(mutate) complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gps1, cops1, csn1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: cops2, csn2, trip15. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chain:
R
(89 residues)
|
|
|
|
|
|
Cryo-em structure of the kbtbd2-crl3~n8(removed)-csn complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cops5, csn5, jab. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: gps1, cops1, csn1. Gene: cops2, csn2, trip15. Gene: cops3, csn3.
|
|
|
Chain:
R
(89 residues)
|
|
|
|
|
|
Cryo-em structure of the kbtbd2-crl3-csn complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cops5, csn5, jab. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: gps1, cops1, csn1. Gene: cops2, csn2, trip15. Gene: cops3, csn3.
|
|
|
Chain:
R
(89 residues)
|
|
|
|
|
|
Cryo-em structure of the cand1-cul3-rbx1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cul3, kiaa0617. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chain:
E
(89 residues)
|
|
|
|
|
|
Cryo-em structure of the kbtbd2-crl3~n8 dimeric complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rbx1, rnf75, roc1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: cul3, kiaa0617. Expression_system_taxid: 7108
|
|
|
Chains:
E, D
(89 residues)
|
|
|
|
|
|
Crystal structure of siah1 sbd bound to axin2 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: siah1, humsiah. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: axin2. Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(190 residues)
|
|
|
|
|
|
The open state of rglg2-vwa
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg2, at5g14420, f18o22.210. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F, G, H, I
(287 residues)
|
|
|
|
|
|
The closed state of rglg2-vwa
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: rglg2, at5g14420, f18o22.210. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A
(271 residues)
|
|
|
|
|
|
Nmr structure of oscie1-ubox s237d mutant
|
|
|
Source: Oryza sativa japonica group. Japanese rice. Organism_taxid: 39947. Gene: pub12, os06g0102700, loc_os06g01304, osjnba0075g19.19-1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(80 residues)
|
|
|
|
|
|
Nmr structure of oscie1-ubox
|
|
|
Source: Oryza sativa japonica group. Japanese rice. Organism_taxid: 39947. Gene: pub12, os06g0102700, loc_os06g01304, osjnba0075g19.19-1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(80 residues)
|
|
|
|
|
|
Cryo-em structure of 8-subunit smc5/6 head region
|
|
|
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Strain: s288c. Gene: smc5. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: smc6. Gene: kre29. Gene: nse5.
|
|
|
Chain:
F
(322 residues)
|
|
|
|
|
|
The structure of rat beta-arrestin1 in complex with a rat mdm2 peptide
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: arrb1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10116
|
|
|
Chain:
E
(15 residues)
|
|
|
|
|
|
Tumor necrosis factor receptor associated factor 6 (traf6) n-terminal domain
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Gene: traf6, rnf85. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(157 residues)
|
|
|
|
|
|
Bre1(mrbd-ring)/rad6-ub/nucleosome complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(64 residues)
|
|
|
|
|
|
Rnf20-rnf40/hrad6a-ub/nucleosome complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h2ac4, h2afm, hist1h2ab, h2ac8, h2afa, hist1h2ae. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h2bc12, h2bft, hirip1, hist1h2bk. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi,
|
|
|
Chains:
A, M
(60 residues)
|
|
|
|
|
|
Protomer 1 and 2 of the asymmetry trimer of the cul2-rbx1-elobc-fem1b ubiquitin ligase complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Gene: elob, tceb2. Expressed in: escherichia coli.
|
|
|
Chain:
R
(70 residues)
|
|
|
|
|
|
Crystal structure of traf7 coiled-coil domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf7, rfwd1, rnf119. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
B, A, C
(92 residues)
|
|
|
|
|
|
Crystal structure of the slf1 brct domain in complex with a rad18 peptide containing ps442 and ps444
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: slf1, ankrd32, brctd1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
C, D
(16 residues)
|
|
|
|
|
|
Crystal structure of the slf1 brct domain in complex with a rad18 peptide containing ps442
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: slf1, ankrd32, brctd1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
C, D
(16 residues)
|
|
|
|
|
|
Crystal structure of mammalian trim71 in complex with lncrna trincr1
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim71, gm1127, lin41. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Synthetic: yes. Organism_taxid: 10090
|
|
|
Chains:
A, B
(275 residues)
|
|
|
|
|
|
Mdm2 bound with a peptoid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(87 residues)
|
|
|
|
|
|
Crystal structure of ubr box of ubr4 apo
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr4, kiaa0462, kiaa1307, rbaf600, zubr1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(73 residues)
|
|
|
|
|
|
Crystal structure of ubr box of yifs-ubr4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr4, kiaa0462, kiaa1307, rbaf600, zubr1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(72 residues)
|
|
|
|
|
|
Structure of crl2appbp2 bound with rxxgp degron (tetramer)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: appbp2, kiaa0228, pat1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cul2. Gene: elob, tceb2. Gene: eloc, tceb1.
|
|
|
Chains:
R, V
(82 residues)
|
|
|
|
|
|
Structure of crl2appbp2 bound with rxxgpaa degron (tetramer)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: appbp2, kiaa0228, pat1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cul2. Gene: elob, tceb2. Gene: eloc, tceb1.
|
|
|
Chains:
R, V
(81 residues)
|
|
|
|
|
|
Structure of crl2appbp2 bound with thE C-degron of mrpl28 (tetramer)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: appbp2, kiaa0228, pat1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cul2. Gene: elob, tceb2. Gene: eloc, tceb1.
|
|
|
Chains:
R, V
(83 residues)
|
|
|
|
|
|
An asymmetry dimer of the cul2-rbx1-elobc-fem1b ubiquitin ligase complexed with bex2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: elob, tceb2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
R
(12 residues)
|
|
|
|
|
|
A novel uhrf1-targeted compound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(193 residues)
|
|
|
|
|
|
Phd finger protein 7 (phf7) in complex with ube2d2
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: phf7. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, C
(265 residues)
|
|
|
|
|
|
Ephd domain of phd finger protein 7 (phf7)
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: phf7. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(117 residues)
|
|
|
|
|
|
Phd finger protein 7 (phf7) fused to ube2d2 via a (gsgg)3 linker
|
|
|
Source: Mus musculus, homo sapiens. House mouse, human. Organism_taxid: 10090, 9606. Gene: phf7, ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(404 residues)
|
|
|
|
|
|
Structure of cul3-rbx1-klhl22 complex without cul3 na motif
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul3. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: klhl22. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 7108
|
|
|
Chain:
R
(39 residues)
|
|
|
|
|
|
Cryo-em structure of hrd1-sel1lx3-xtp3b complex in c1 symmetry
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: syvn1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: sel1l. Gene: erlec1. Expression_system_taxid: 9606
|
|
|
Chains:
A, B
(266 residues)
|
|
|
|
|
|
Cryo-em structure of hrd1-sel1lfl-xtp3b complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: syvn1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Gene: erlec1. Gene: sel1l, tsa305, unq128/pro1063.
|
|
|
Chains:
A, B
(266 residues)
|
|
|
|
|
|
Cryo-em structure of hrd1-sel1l-xtp3b (state d1) complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: sel1l, tsa305, unq128/pro1063. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: erlec1, c2orf30, xtp3tpb, unq1878/pro4321. Gene: syvn1, hrd1, kiaa1810. Expression_system_taxid: 9606
|
|
|
Chains:
A, B
(266 residues)
|
|
|
|
|
|
Cullin3-klhl22-rbx1 e3 ligase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: klhl22. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: cul3, kiaa0617. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 9606
|
|
|
Chains:
E, F
(52 residues)
|
|
|
|
|
|
Cand1-cul1-rbx1-skp1-skp2-cks1-cdk2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3).
|
|
|
Chain:
B
(88 residues)
|
|
|
|
|
|
Cand1-cul1-rbx1-dcnl1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3).
|
|
|
Chain:
B
(88 residues)
|
|
|
|
|
|
Cand1-cul1-rbx1-skp1-skp2-dcnl1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3).
|
|
|
Chain:
B
(88 residues)
|
|
|
|
|
|
Partially dissociated cand1-cul1-rbx1-skp1-skp2-cks1-cdk2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Gene: cand1, kiaa0829, tip120, tip120a. Expressed in: escherichia coli bl21(de3).
|
|
|
Chain:
B
(37 residues)
|
|
|
|
|
|
Cryo-em structure of doa10 in msp1e3d1
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ssm4, doa10, yil030c, yi3299.01c, yi9905.18c. Expressed in: trichoplusia ni. Expression_system_taxid: 7111
|
|
|
Chain:
A
(880 residues)
|
|
|
|
|
|
Crystal structure of trim58 pry-spry domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim58. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(199 residues)
|
|
|
|
|
|
Crystal structure of the trim58 pry-spry domain in complex with trim- 473
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim58. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(181 residues)
|
|
|
|
|
|
Cryo-em structure of doa10 with ring domain in msp1e3d1
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ssm4, doa10, yil030c, yi3299.01c, yi9905.18c. Expressed in: trichoplusia ni. Expression_system_taxid: 7111
|
|
|
Chain:
A
(973 residues)
|
|
|
|
|
|
Catalytic module of human ctlh e3 ligase bound to multiphosphorylated ube2h~ubiquitin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rmnd5a. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: ube2h. Expressed in: trichoplusia. Expression_system_taxid: 7110.
|
|
|
Chains:
b, i
(296 residues)
|
|
|
|
|
|
Catalytic module of yeast gid e3 ligase bound to multiphosphorylated ubc8~ubiquitin
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: rmd5, gid2, ydr255c, yd9320a.05c. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: fyv10, gid9, yil097w. Gene: ubc8, gid3, yel012w. Homo sapiens.
|
|
|
Chains:
2, 9
(355 residues)
|
|
|
|
|
|
Human rybp-prc1 bound to mononucleosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bmi1, pcgf4, rnf51. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: rnf2, bap1, ding, hipi3, ring1b. Drosophila melanogaster. Fruit fly.
|
|
|
Chains:
L, N
(101 residues)
|
|
|
|
|
|
K48-linked ubiquitin chain formation with a cullin-ring e3 ligase and cdc34: nedd8-cul2-rbx1-elob/c-fem1c with trapped ube2r2-donor ub- acceptor ub-sil1 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2r2, cdc34b, ubc3b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: ubc, sil1, unq545/pro836. Gene: fem1c, kiaa1785. Gene: rbx1, rnf75, roc1.
|
|
|
Chain:
K
(78 residues)
|
|
|
|
|
|
Crystal structure of mdm2 with brigimadlin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(94 residues)
|
|
|
|
|
|
Structure of cul9-rbx1 ubiquitin e3 ligase complex - hexameric assembly
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul9, h7ap1, kiaa0708, parc. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 9606
|
|
|
Chains:
C, D, G, H, K, L
(14 residues)
|
|
|
|
|
|
Structure of cul9-rbx1 ubiquitin e3 ligase complex in unneddylated and neddylated conformation - focused cullin dimer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul9, h7ap1, kiaa0708, parc. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rbx1, rnf75, roc1. Organism_taxid: 9606
|
|
|
Chains:
C, D
(79 residues)
|
|
|
|
|
|
Ubiquitin ligation to substrate by a cullin-ring e3 ligase & cdc34: nedd8-cul2-rbx1-elob/c-fem1c with trapped ube2r2~donor ub-sil1 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: fem1c, kiaa1785. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
R
(78 residues)
|
|
|
|
|
|
Cryo-em structure of sidh from legionella pneumophila in complex with lubx
|
|
|
Source: Escherichia coli 'bl21-gold(de3)plyss ag'. Organism_taxid: 866768. Legionella pneumophila. Organism_taxid: 446. Gene: c3927_14265. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Gene: c3927_14270. Expressed in: escherichia coli.
|
|
|
Chain:
D
(188 residues)
|
|
|
|
|
|
Crystal structure of the e3 ubiquitin ligase cbl-b with an allosteric inhibitor (benzodiazepine hts hit compound 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(384 residues)
|
|
|
|
|
|
Crystal structure of the e3 ubiquitin ligase cbl-b with an allosteric inhibitor (wo2020264398 ex23)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(384 residues)
|
|
|
|
|
|
Crystal structure of the e3 ubiquitin ligase cbl-b with an allosteric inhibitor (benzodiazepine compound 25)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(377 residues)
|
|
|
|
|
|
Crystal structure of cbl-b in complex with an allosteric inhibitor (compound 9)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(384 residues)
|
|
|
|
|
|
Crystal structure of cbl-b in complex with an allosteric inhibitor (compound 8)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(386 residues)
|
|
|
|
|
|
Crystal structure of cbl-b in complex with an allosteric inhibitor (compound 30)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(384 residues)
|
|
|
|
|
|
Crystal structure of cbl-b in complex with an allosteric inhibitor (compound 31)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cblb. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(384 residues)
|
|
|
|
|
|
Protac-mediated complex of kras with vhl/elongin-b/elongin-c/cullin- 2/rbx1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vhl. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: elob, tceb2. Gene: eloc, tceb1. Gene: cul2.
|
|
|
Chain:
E
(88 residues)
|
|
|
|
|
|
Endosomal membrane tethering complex corvet
|
|
|
Source: Saccharomyces cerevisiae. Brewer's yeast. Organism_taxid: 4932. Gene: vps8, vpt8, yal002w, fun15. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: vps33, slp1, vam5, ylr396c, l8084.15. Gene: vps16, vam9, vpt16, ypl045w. Gene: pep5, end1, vam1, vpl9, vps11, vpt11, ymr231w, ym9959.13.
|
|
|
Chain:
A
(969 residues)
|
|
|
|
|
|
Crystal structure of human trim7 pryspry domain bound to (3- phenoxybenzoyl)-l-glutamine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(169 residues)
|
|
|
|
|
|
Crystal structure of human trim7 pryspry domain bound to (2-(1- oxoisoindolin-2-yl)-3-phenylpropanoyl)-l-glutamine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(172 residues)
|
|
|
|
|
|
Crystal structure of human trim7 pryspry domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim7. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(172 residues)
|
|
|
|
|
|
Ubiquitin ligation to neosubstrate by a cullin-ring e3 ligase & cdc34: nedd8-cul2-rbx1-elob/c-vhl-mz1 with trapped ube2r2~donor ub-brd4 bd2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: rbx1, rnf75, roc1. Gene: ube2r2, cdc34b, ubc3b. Expressed in: escherichia coli bl21.
|
|
|
Chain:
R
(79 residues)
|
|
|
|
|
|
Dtx1 wwe domain in complex with atp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dtx1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(165 residues)
|
|
|
|
|
|
Dtx1 wwe domain in complex with adp bound to wwe1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dtx1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(164 residues)
|
|
|
|
|
|
Dtx1 wwe domain in complex with adp bound to wwe2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dtx1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(165 residues)
|
|
|
|
|
|
The d2 domain of human dtx3l
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dtx3l, bbap. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B, C, D
(60 residues)
|
|
|
|
|
|
Structure of the znf domain from human roquin-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rc3h1, kiaa2025, rnf198. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
|
|
|
Chain:
A
(48 residues)
|
|
|
|
|
|
Structure of cul9-rbx1 ubiquitin e3 ligase complex in unneddylated conformation - symmetry expanded unneddylated dimer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul9, h7ap1, kiaa0708, parc. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rbx1, rnf75, roc1. Expression_system_taxid: 9606
|
|
|
Chains:
C, D
(80 residues)
|
|
|
|
|
|
Crystal structure of brca1 brcts in complex with a rif1 phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D
(210 residues)
|
|
|
|
|
|
Open non-crosslinked structure brd4bd2-mz1-(nedd8)-crl2vhl
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brd4, hunk1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: vhl. Gene: elob, tceb2. Gene: cul2.
|
|
|
Chain:
R
(73 residues)
|
|
|
|
|
|
(Nedd8)-crl2vhl-mz1-brd4bd2-ub(g76s, k48c)-ube2r1(c93k, s138c, c191s, c223s)-ub
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brd4, hunk1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: vhl. Gene: eloc, tceb1. Gene: elob, tceb2.
|
|
|
Chain:
R
(71 residues)
|
|
|
|
|
|
Structure of the e3 ubiquitin ligase rnf213, determined by cryoem
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf213, alo17, c17orf27, kiaa1554, kiaa1618, mystr. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
|
|
|
Chain:
A
(4387 residues)
|
|
|
|
|
|
Hydrophobic interactions drive the tetrameric assembly of the trim45 coiled-coil domain
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim45. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D
(80 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a. No density for ub.) (Class 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a. No density for ub.) (Class 2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a. No density for ub.) (Class 3)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a. No density for ub.) (Class 4)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a. No density for ub.) (Class 5)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a. No density for ub.) (Class 6)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c (ubch5c chemically conjugated to histone h2a)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a) (class 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(87 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a) (class 2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a) (class 3)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a) (class 4)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a) (class 5)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c~ub (ubch5c chemically conjugated to histone h2a) (class 6)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c with backside ubiquitin (ubch5c chemically conjugated to histone h2a) (class 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168 and ubch5c with backside ubiquitin (ubch5c chemically conjugated to histone h2a) (class 2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(85 residues)
|
|
|
|
|
|
Chip-tpr in complex with thE C-terminus of chic2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D
(128 residues)
|
|
|
|
|
|
Structure of bre1-nucleosome complex - state3
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Saccharomyces cerevisiae.
|
|
|
Chains:
K, L
(69 residues)
|
|
|
|
|
|
Structure of bre1-nucleosome complex - state2
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic construct. Organism_taxid: 32630. Saccharomyces cerevisiae. Baker's yeast.
|
|
|
Chains:
K, L
(69 residues)
|
|
|
|
|
|
Structure of bre1-nucleosome complex - state1
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic construct. Organism_taxid: 32630. Saccharomyces cerevisiae (strain atcc 204508 / s288c).
|
|
|
Chains:
K, L
(69 residues)
|
|
|
|
|
|
Sars-cov-2 orf3a peptide in complex with traf3 traf domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf3, cap-1, craf1, trafamn. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Expression_system_variant: ripl. Synthetic: yes. Severe acute respiratory syndrome coronavirus
|
|
|
Chains:
A, B, C, D, E, F
(190 residues)
|
|
|
|
|
|
Sars-cov-2 orf3a peptide in complex with traf2 traf domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf2, trap3. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Expression_system_variant: ripl. Synthetic: yes. Severe acute respiratory syndrome coronavirus
|
|
|
Chains:
A, B, C, D, E, F
(168 residues)
|
|
|
|
|
|
Cryo-em structure of e3 ubiquitin ligase doa10 from saccharomyces cerevisiae
|
|
|
Source: Saccharomyces cerevisiae by4741. Organism_taxid: 1247190
|
|
|
Chain:
A
(843 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle ubiquitylated at histone h2a k15 in complex with rnf168 (class 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(14 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle ubiquitylated at histone h2a k15 in complex with rnf168 (class 2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(14 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle ubiquitylated at histone h2a k15 in complex with rnf168 (class 3)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(30 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle ubiquitylated at histone h2a lysine 15 in complex with rnf168-ubch5c (class 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(88 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle ubiquitylated at histone h2a lysine 15 in complex with rnf168-ubch5c (class 2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(88 residues)
|
|
|
|
|
|
Crystal structure of the co-expressed sds22:pp1:i3 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ppp1ca, ppp1a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: expi293. Gene: ppp1r7, sds22. Gene: ppp1r11, hcgv, tcte5.
|
|
|
Chain:
C
(24 residues)
|
|
|
|
|
|
Cryo-em structure of dimeric scf-fbxl17-bach1btb e3 ligase complex close conformation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: rbx1, rnf75, roc1. Gene: skp1, emc19, ocp2, skp1a, tceb1l. Expressed in: trichoplusia ni.
|
|
|
Chains:
B, I
(20 residues)
|
|
|
|
|
|
Cryo-em structure of the human nucleosome core particle in complex with rnf168-ubch5c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi, hist1h3f, h3c8, h3fh, hist1h3g, h3c10, h3fk, hist1h3h, h3c11, h3ff, hist1h3i, h3c12, h3fj, hist1h3j. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
K
(88 residues)
|
|
|
|
|
|
Crystal structure of rnf168 (ring)-ubch5c fused to h2a-h2b via a 2- residue linker
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168, ube2d3, ubc5c, ubch5c, h2bc21, h2bfq, hist2h2be, h2ac4, h2afm, hist1h2ab, h2ac8, h2afa, hist1h2ae. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, a
(426 residues)
|
|
|
|
|
|
Crystal structure of rnf168 (ring)-ubch5c fused to h2a-h2b via a 4- residue linker
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168, ube2d3, ubc5c, ubch5c, h2bc21, h2bfq, hist2h2be, h2ac4, h2afm, hist1h2ab, h2ac8, h2afa, hist1h2ae. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, a
(432 residues)
|
|
|
|
|
|
Crystal structure of rnf168 (ring)-ubch5c fused to h2a-h2b via a 12- residue linker
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168, ube2d3, ubc5c, ubch5c, h2bc21, h2bfq, hist2h2be, h2ac4, h2afm, hist1h2ab, h2ac8, h2afa, hist1h2ae. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
K
(427 residues)
|
|
|
|
|
|
Crystal structure of rnf168 (ring)-ubch5c fused to h2a-h2b via a 20- residue linker (crystallization condition 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168, ube2d3, ubc5c, ubch5c, h2bc21, h2bfq, hist2h2be, h2ac4, h2afm, hist1h2ab, h2ac8, h2afa, hist1h2ae. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(408 residues)
|
|
|
|
|
|
Crystal structure of rnf168 (ring)-ubch5c fused to h2a-h2b via a 20- residue linker (crystallization condition 2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168, ube2d3, ubc5c, ubch5c, h2bc21, h2bfq, hist2h2be, h2ac4, h2afm, hist1h2ab, h2ac8, h2afa, hist1h2ae. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(420 residues)
|
|
|
|
|
|
Crystal structure of rnf168 (ring)-ubch5c fused to h2a-h2b via a 20- residue linker (condition 2. Ring not modeled in density)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168, ube2d3, ubc5c, ubch5c, h2bc21, h2bfq, hist2h2be, h2ac4, h2afm, hist1h2ab, h2ac8, h2afa, hist1h2ae. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(332 residues)
|
|
|
|
|
|
Crystal structure of rnf168 (ring)-ubch5c fused to h2a-h2b via a 26- residue linker (ring not modeled in density)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf168, ube2d3, ubc5c, ubch5c, h2bc21, h2bfq, hist2h2be, h2ac4, h2afm, hist1h2ab, h2ac8, h2afa, hist1h2ae. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(331 residues)
|
|
|
|
|
|
Ubch5b-ring3 of mib1 fusion structure
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b, mib1, dip1, kiaa1323, zzank2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A
(213 residues)
|
|
|
|
|
|
Ank repeat of mib1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mib1. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(344 residues)
|
|
|
|
|
|
Crystal structure of the ring domain of human xiap treated with arsenic trioxide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(61 residues)
|
|
|
|
|
|
Crystal structure of the ring domain of human xiap
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: xiap, api3, birc4, iap3. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(62 residues)
|
|
|
|
|
|
The complex structure of cul2-vcb-protac-wee1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: insect cell expression vector ptie1. Expression_system_taxid: 266783. Gene: rbx1. Gene: vhl. Expressed in: escherichia coli.
|
|
|
Chain:
R
(82 residues)
|
|
|
|
|
|
Cryo-em structure of 6-subunit smc5/6 head region
|
|
|
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Strain: s288c. Gene: smc6. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: smc5. Gene: nse1. Gene: nse3.
|
|
|
Chain:
F
(313 residues)
|
|
|
|
|
|
Crystal structure of human dppa3 in complex with human uhrf1 phd domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: unidentified plasmid. Expression_system_taxid: 45202. Gene: dppa3, stellar. Expression_system_taxid: 45202
|
|
|
Chain:
A
(66 residues)
|
|
|
|
|
|
Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with thE C-degron of ccdc89 (conformation 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: fem1b, f1aa, kiaa0396. Gene: eloc, tceb1. Gene: elob, tceb2.
|
|
|
Chains:
J, I
(83 residues)
|
|
|
|
|
|
Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with thE C-degron of ccdc89 (conformation 2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: eloc, tceb1. Gene: elob, tceb2. Gene: rbx1, rnf75, roc1.
|
|
|
Chains:
I, E
(75 residues)
|
|
|
|
|
|
Cryo-em structure of neddylated cul2-rbx1-elob-eloc-fem1b bound with thE C-degron of cdk5r1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: elob, tceb2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rbx1, rnf75, roc1. Gene: eloc, tceb1. Gene: cul2.
|
|
|
Chains:
F, J
(85 residues)
|
|
|
|
|
|
Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with thE C-degron of cux1 (conformation 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: fem1b, f1aa, kiaa0396. Gene: eloc, tceb1. Gene: elob, tceb2.
|
|
|
Chains:
J, I
(83 residues)
|
|
|
|
|
|
Cryo-em structure of neddylated cul2-rbx1-elob-eloc-fem1b bound with thE C-degron of ccdc89 (conformation 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: elob, tceb2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rbx1, rnf75, roc1. Gene: eloc, tceb1. Gene: cul2.
|
|
|
Chains:
F, J
(85 residues)
|
|
|
|
|
|
Cryo-em structure of neddylated cul2-rbx1-elob-eloc-fem1b bound with thE C-degron of ccdc89 (conformation 2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rbx1, rnf75, roc1. Gene: eloc, tceb1. Gene: elob, tceb2.
|
|
|
Chains:
J, B
(83 residues)
|
|
|
|
|
|
Cryo-em structure of lgr4 in complex with rspo1 and rnf43
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lgr4. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rspo1. Gene: rnf43. Expression_system_taxid: 7108
|
|
|
Chain:
C
(137 residues)
|
|
|
|
|
|
Cryo-em structures of rnf168/ubch5c-ub in complex with h2ak13ub nucleosomes determined by intein-based e2-ub-ncp conjugation strategy
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c15, hist2h3a, h3c14, h3f2, h3fm, hist2h3c, h3c13, hist2h3d. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h4c1, h4/a, h4fa, hist1h4a, h4c2, h4/i, h4fi, hist1h4b, h4c3, h4/g, h4fg, hist1h4c, h4c4, h4/b, h4fb, hist1h4d, h4c5, h4/j, h4fj, hist1h4e, h4c6, h4/c, h4fc, hist1h4f, h4c8, h4/h, h4fh, hist1h4h,
|
|
|
Chain:
L
(83 residues)
|
|
|
|
|
|
Cryo-em structures of rnf168/ubch5c-ub/nucleosomes complex determined by activity-based chemical trapping strategy
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c15, hist2h3a, h3c14, h3f2, h3fm, hist2h3c, h3c13, hist2h3d. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h4c1, h4/a, h4fa, hist1h4a, h4c2, h4/i, h4fi, hist1h4b, h4c3, h4/g, h4fg, hist1h4c, h4c4, h4/b, h4fb, hist1h4d, h4c5, h4/j, h4fj, hist1h4e, h4c6, h4/c, h4fc, hist1h4f, h4c8, h4/h, h4fh, hist1h4h,
|
|
|
Chain:
L
(55 residues)
|
|
|
|
|
|
Cryo-em structures of rnf168/ubch5c-ub in complex with h2ak13ub nucleosomes determined by activity-based chemical trapping strategy (adjacent h2ak13/15 dual-monoubiquitination)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3c15, hist2h3a, h3c14, h3f2, h3fm, hist2h3c, h3c13, hist2h3d. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h4c1, h4/a, h4fa, hist1h4a, h4c2, h4/i, h4fi, hist1h4b, h4c3, h4/g, h4fg, hist1h4c, h4c4, h4/b, h4fb, hist1h4d, h4c5, h4/j, h4fj, hist1h4e, h4c6, h4/c, h4fc, hist1h4f, h4c8, h4/h, h4fh, hist1h4h,
|
|
|
Chain:
L
(54 residues)
|
|
|
|
|
|
The pentamera complex of lgr4-rspo2-znrf3(delta ring)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lgr4, gpr48. Expressed in: homo sapiens. Expression_system_taxid: 9606. Camelus bactrianus. Organism_taxid: 9837. Expressed in: escherichia coli.
|
|
|
Chains:
C, H
(181 residues)
|
|
|
|
|
|
Lgr4-rspo2-znrf3 ring domain (1:2:2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lgr4, gpr48. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: znrf3, kiaa1133, rnf203. Camelus bactrianus. Organism_taxid: 9837.
|
|
|
Chains:
C, E
(185 residues)
|
|
|
|
|
|
Lgr4-rspo2-znrf3(1:1:1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lgr4, gpr48. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: znrf3. Camelus bactrianus. Organism_taxid: 9837.
|
|
|
Chain:
C
(173 residues)
|
|
|
|
|
|
Cryo-em structure of the chlamydomonas c Complex
|
|
|
Source: Chlamydomonas reinhardtii. Organism_taxid: 3055. Organism_taxid: 3055
|
|
|
Chains:
q, r, s, t
(106 residues)
|
|
|
|
|
|
The closed state of rglg5-vwa
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: rglg5, at1g67800. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(272 residues)
|
|
|
|
|
|
Crystal structure of ttd-phd domain of uhrf1 in complex with mstella peptide (residues 85-119)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Mus musculus. House mouse.
|
|
|
Chains:
A, B
(222 residues)
|
|
|
|
|
|
Crystal structure of phd domain of uhrf1 in complex with mstella peptide (residues 85-119)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Mus musculus. House mouse.
|
|
|
Chains:
A, C
(68 residues)
|
|
|
|
|
|
Crystal structure of ttd-phd domain of uhrf1 in complex with hstella peptide (residues 75-121)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, C, E, G
(227 residues)
|
|
|
|
|
|
Crystal structure of phd domain of uhrf1 in complex with hstella peptide (residues 75-121)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, C, E, G
(70 residues)
|
|
|
|
|
|
Crystal structure of trim21 pryspry (d355a) in complex with acepromazine.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim21, rnf81, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(182 residues)
|
|
|
|
|
|
Lgr4-rspo2-znrf3 (2:2:2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lgr4, gpr48. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: znrf3, kiaa1133, rnf203. Camelus bactrianus. Organism_taxid: 9837.
|
|
|
Chains:
C, H
(181 residues)
|
|
|
|
|
|
Zz-domain of the arabidopsis thaliana e3 ubiquitin-protein ligase prt1
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt1, at3g24800, k7p8.9. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(59 residues)
|
|
|
|
|
|
Y-degron fused zz-domain of the arabidopsis thaliana e3 ubiquitin- protein ligase prt1
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt1, at3g24800, k7p8.9. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D, E, F
(68 residues)
|
|
|
|
|
|
F-degron fused zz-domain of the arabidopsis thaliana e3 ubiquitin- protein ligase prt1
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt1, at3g24800, k7p8.9. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D, E, F
(68 residues)
|
|
|
|
|
|
W-degron fused zz-domain of the arabidopsis thaliana e3 ubiquitin- protein ligase prt1
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: prt1, at3g24800, k7p8.9. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(68 residues)
|
|
|
|
|
|
Cluster structure of the baff-baffr-traf3 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf3, cap-1, craf1, trafamn. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: tnfrsf13c, baffr, br3. Expressed in: homo sapiens. Expression_system_taxid: 9606.
|
|
|
Chains:
A, B, C, G, H, I, M, N, O, S, T, U, Y, Z, a, e, f, g, k, l, m
(179 residues)
|
|
|
|
|
|
Structure of the magea4 mhd-rad18 r6bd complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: magea4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
B, D
(20 residues)
|
|
|
|
|
|
Crystal structure of mdm2-peptide complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, C
(94 residues)
|
|
|
|
|
|
Structure of human ubr4-kcmf1-cam e3 ligase complex (silencing factor of the integrated stress response, sifi)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: hek293t. Cell_line: hek293t
|
|
|
Chains:
A, B, E, F
(3917 residues)
|
|
|
|
|
|
Ncprc1rybp bound to singly modified h2ak119ub nucleosome
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens.
|
|
|
Chain:
L
(101 residues)
|
|
|
|
|
|
Ncprc1rybp bound to h2ak119ub/h1.4 chromatosome
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human.
|
|
|
Chain:
L
(101 residues)
|
|
|
|
|
|
Ncprc1rybp bound to unmodified nucleosome
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human.
|
|
|
Chain:
L
(101 residues)
|
|
|
|
|
|
Structure of ubr1-rff complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(77 residues)
|
|
|
|
|
|
Structure of ubr2-rff complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr2, c6orf133, kiaa0349. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(72 residues)
|
|
|
|
|
|
Structure of ubr2-ryf complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr2, c6orf133, kiaa0349. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(75 residues)
|
|
|
|
|
|
Structure of ubr2-rwf complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr2, c6orf133, kiaa0349. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(70 residues)
|
|
|
|
|
|
Chip u-box dimer bound to fab 2f1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(75 residues)
|
|
|
|
|
|
Structure of the yeast post-catalytic p complex spliceosome at 2.3 angstrom resolution
|
|
|
Source: Saccharomyces cerevisiae. Brewer's yeast. Organism_taxid: 4932. Synthetic: yes. Gene: prp22, yer013w. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Organism_taxid: 4932
|
|
|
Chains:
t, u, v, w
(132 residues)
|
|
|
|
Bound ligand:
|
Het Group GTP
is 96.88% similar to
enzyme reactant ATP
|
|
|
|
|
|
|
Chip-tpr in complex with the hsp70 tail
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(129 residues)
|
|
|
|
|
|
Chip-tpr in complex with the phosphorylated hsp70 tail
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: stub1, chip, pp1131. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(132 residues)
|
|
|
|
|
|
Structure of cbl-tkbd bound to ubiquitin-fused cblock peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cbl, cbl2, rnf55. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_variant: e. Coli. Gene: ubc.
|
|
|
Chains:
A, C
(307 residues)
|
|
|
|
|
|
Structure of a b-state intermediate committed to discard (bd-i state)
|
|
|
Source: Schizosaccharomyces pombe. Fission yeast. Organism_taxid: 4896. Organism_taxid: 4896
|
|
|
Chains:
S, T, U, V
(132 residues)
|
|
|
|
|
|
Structure of a b-state intermediate committed to discard (bd-ii state)
|
|
|
Source: Schizosaccharomyces pombe. Fission yeast. Organism_taxid: 4896. Organism_taxid: 4896
|
|
|
Chains:
S, T, U, V
(132 residues)
|
|
|
|
|
|
Crystal structure of hdm2 in complex with a peptidic ligand containing a di-urea insert.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B, E, F, I, J
(86 residues)
|
|
|
|
|
|
Structure of human rnf213 bound to the secreted effector ipah1.4 from shigella flexneri
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf213, alo17, c17orf27, kiaa1554, kiaa1618, mystr. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Shigella flexneri 5a str. M90t. Organism_taxid: 1086030. Gene: ipah1.4, sf_p0265.
|
|
|
Chains:
A, B
(4529 residues)
|
|
|
|
|
|
Structure of human rnf213 bound to the secreted effector ipah2.5 from shigella flexneri
|
|
|
Source: Shigella flexneri 5a str. M90t. Organism_taxid: 1086030. Strain: m90t (5a). Gene: ipah2.5, sf_p0054. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
B, A
(237 residues)
|
|
|
|
|
|
Crystal structure of the ring-znf1 fragment of siah1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: siah1, humsiah. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(97 residues)
|
|
|
|
|
|
Crystal structure of apo trim24 phd-brd in c121 space group
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(177 residues)
|
|
|
|
|
|
Crystal structure of hei10
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ccnb1ip1, c14orf18, hei10. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(177 residues)
|
|
|
|
|
|
Hdm2 complexed with stapled peptide-like ligand
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm2. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B, C, D
(86 residues)
|
|
|
|
|
|
Crystal structure of trim21 pry-spry domain bound to suramin
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: trim21, ro52, ssa1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
B
(185 residues)
|
|
|
|
|
|
Crystal structure of the salmonella effector ssph1
|
|
|
Source: Salmonella enterica subsp. Enterica serovar typhimurium. Organism_taxid: 90371. Gene: ssph1, stm14_1483. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(540 residues)
|
|
|
|
|
|
Structure of zincore (sephs1:qrich1) binding to zfp91 on DNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: zfp91, znf757, fksg11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 266783. Gene: sephs1, seld, sps, sps1. Expression_system_taxid: 7108. Gene: qrich1.
|
|
|
Chain:
A
(154 residues)
|
|
|
|
|
|
Structure of 2x zincore (sephs1:qrich1) binding to zfp91 on DNA
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: zfp91, znf757, fksg11. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: sephs1, seld, sps, sps1. Expressed in: insect cell expression vector ptie1. Expression_system_taxid: 266783.
|
|
|
Chain:
A
(154 residues)
|
|
|
|
|
|
Crystal structure of the pellino 1 fha domain in complex with a mdc1- tqxf phosphopeptide.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: peli1, prism. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
B, A
(237 residues)
|
|
|
|
|
|
Cryo-em structure of the rnf168(1-193)/ubch5c-ub ubiquitylation module bound to h1.0-k63-ub3 modified chromatosome
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h1-0, h1f0, h1fv. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h3c15, hist2h3a, h3c14, h3f2, h3fm, hist2h3c, h3c13, hist2h3d. Gene: h4c1, h4/a, h4fa, hist1h4a, h4c2, h4/i, h4fi, hist1h4b, h4c3, h4/g, h4fg, hist1h4c, h4c4, h4/b, h4fb, hist1h4d, h4c5, h4/j, h4fj,
|
|
|
Chain:
L
(83 residues)
|
|
|
|
|
|
Crystal structure of trim25 pspry
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim25, efp, rnf147, znf147. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F, G, H, I, J, K, L
(195 residues)
|
|
|
|
|
|
Cryo-em structure of neddylated cul2-rbx1-elobc-fem1b homodimer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: eloc, tceb1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
E, H
(72 residues)
|
|
|
|
|
|
Cryo-em structure of neddylated cul2-rbx1-elobc-fem1b homodimer complexed with fnip1 degron
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: rbx1, rnf75, roc1. Gene: eloc, tceb1. Expressed in: escherichia coli.
|
|
|
Chains:
E, H
(72 residues)
|
|
|
|
|
|
Cryo-em structure of crl2-fem1b (dimer 1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: eloc, tceb1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: elob, tceb2. Gene: rbx1, rnf75, roc1. Gene: cul2.
|
|
|
Chains:
I, E
(73 residues)
|
|
|
|
|
|
Cryo-em structure of crl2-fem1b (dimer 2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: elob, tceb2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cul2. Gene: eloc, tceb1. Gene: fem1b, f1aa, kiaa0396.
|
|
|
Chains:
E, I
(18 residues)
|
|
|
|
|
|
Cryo-em structure of crl2-fem1b bound with tom20(tetramer)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cul2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: eloc, tceb1. Gene: elob, tceb2. Gene: rbx1, rnf75, roc1.
|
|
|
Chains:
I, N
(71 residues)
|
|
|
|
|
|
Cryo-em structure of the cul1-rbx1-skp1-fbxo4 scf ubiquition ligase complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fbxo4, fbx4. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cul1. Gene: skp1, emc19, ocp2, skp1a, tceb1l. Gene: rbx1, rnf75, roc1.
|
|
|
Chain:
R
(16 residues)
|
|
|
|
|
|
Kcmf1 zn-coordinating domains with rckg peptide (sulfonic cysteine)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kcmf1, figc, zzz1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(120 residues)
|
|
|
|
|
|
Cryoem structure of mouse rag sec-phd
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli.
|
|
|
Chains:
A, C
(548 residues)
|
|
|
|
|
|
Cryoem structure of mouse rag sec-0
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli.
|
|
|
Chains:
A, C
(548 residues)
|
|
|
|
|
|
Cryoem structure of mouse rag sec-2dna
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli.
|
|
|
Chains:
A, C
(548 residues)
|
|
|
|
|
|
Crystal structure of rnf213 ring domain bound to ipah1.4 lrr domain
|
|
|
Source: Shigella flexneri 5a str. M90t. Organism_taxid: 1086030. Gene: ekn05_024115. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf213, alo17, c17orf27, kiaa1554, kiaa1618, mystr.
|
|
|
Chains:
B, C
(235 residues)
|
|
|
|
|
|
Cryoem structure of mouse rag sec-1dna (12rss side)
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli.
|
|
|
Chains:
A, C
(618 residues)
|
|
|
|
|
|
Cryoem structure of mouse rag sec-1dna (23rss side)
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rag1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: rag2, rag-2. Synthetic: yes. Escherichia coli.
|
|
|
Chains:
A, C
(618 residues)
|
|
|
|
|
|
Crystal structure of nhl domain of human e3 ubiquitin-protein ligase trim71
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim71, lin41. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
|
|
|
Chain:
A
(277 residues)
|
|
|
|
|
|
Cryo-em structure of human rnf213
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf213. Expressed in: homo sapiens. Expression_system_taxid: 9606
|
|
|
Chain:
A
(4471 residues)
|
|
|
|
|
|
Cryo-em focused refined map of human rnf213 e3 module and ipah1.4 lrr domain
|
|
|
Source: Shigella flexneri. Organism_taxid: 623. Gene: ipah1.4, sf_p0265. Expressed in: homo sapiens. Expression_system_taxid: 9606. Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf213.
|
|
|
Chains:
B, A
(235 residues)
|
|
|
|
|
|
Cryo-em structure of lgr4-rspo2-znrf3 complex (1:1:2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: znrf3, kiaa1133, rnf203. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: lgr4, gpr48. Gene: rspo2, unq9384/pro34209. Expression_system_taxid: 9606
|
|
|
Chains:
B, D
(191 residues)
|
|
|
|
|
|
Cryo-em structure of lgr4-rspo2-znrf3 complex (2:2:2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lgr4, gpr48. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: znrf3, kiaa1133, rnf203. Gene: rspo2, unq9384/pro34209. Expression_system_taxid: 9606
|
|
|
Chains:
C, E
(190 residues)
|
|
|
|
|
|
Cryo-em structure of the cul1-rbx1-skp1-fbxo3 scf ubiquition ligase complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: skp1, emc19, ocp2, skp1a, tceb1l. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: fbxo3, fbx3. Gene: rbx1, rnf75, roc1. Gene: cul1.
|
|
|
Chain:
R
(16 residues)
|
|
|
|
|
|
Cryo-em structure of ufd2/ubc4-ub in complex with k29-linked diub (monomeric conformation)
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Organism_taxid: 559292. Gene: ubc4, ybr082c, ybr0745. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
A
(802 residues)
|
|
|
|
|
|
Cryo-em structure of ufd2/ubc4-ub in complex with k29-linked triub (dimeric conformation)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba80, ubcep1. Saccharomyces cerevisiae (strain atcc 204508 / s288c).
|
|
|
Chains:
A, a
(917 residues)
|
|
|
|
|
|
Cryo-em structure of rnf168'-rnf168-ubch5c complex bound to nucleosome
|
|
|
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Gene: loc121398065, loc108703785, loc121398067. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: loc121398084. Gene: loc494591, h2ac14.L, hist1h2aj, hist1h2aj.L. Gene: loc108704303.
|
|
|
Chain:
K
(83 residues)
|
|
|
|
|
|
Dimer of crl2-fem1b bound with pld6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pld6. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cul2. Gene: eloc, tceb1. Gene: rbx1, rnf75, roc1.
|
|
|
Chains:
E, I
(86 residues)
|
|
|
|
|
|
Cryo-em structure of sestrin2 bound human gator2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mios. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: wdr24. Gene: wdr59, kiaa1923, fp977. Gene: seh1l, sec13l, seh1.
|
|
|
Chains:
C, M
(573 residues)
|
|
|
|
|
|
Cryo-em structure of castor1 bound human gator2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mios. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: wdr24. Gene: wdr59, kiaa1923, fp977. Gene: seh1l, sec13l, seh1.
|
|
|
Chains:
C, M
(577 residues)
|
|
|
|
|
|
Cryo-em structure of dual sensor bound gator2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mios. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: wdr24, c16orf21, jfp7. Gene: wdr59, kiaa1923, fp977. Gene: seh1l, sec13l, seh1.
|
|
|
Chains:
C, I
(568 residues)
|
|
|
|
|
|
Cryo-em structure of hrd1-sel1lx3-xtp3b complex in c2 symmetry
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: syvn1, hrd1, kiaa1810. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: sel1l, tsa305, unq128/pro1063. Gene: erlec1, c2orf30, xtp3tpb, unq1878/pro4321. Expression_system_taxid: 9606
|
|
|
Chains:
A, B
(266 residues)
|
|
|
|
|
|
Cryo-em structure of ufd2/ubc4-ub complex with k29triub(monomeric conformation)
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Brewer's yeast. Organism_taxid: 559292. Gene: ubc4, ybr082c, ybr0745. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
|
|
|
Chain:
A
(802 residues)
|
|
|
|
|
|
Structure of ubr1-rwa complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(77 residues)
|
|
|
|
|
|
Crystal structure of the ark2c-ubc13~ub-mms2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ark2c, rnf165. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ube2n, blu. Gene: ube2v2, mms2, uev2. Gene: ubc.
|
|
|
Chain:
A
(72 residues)
|
|
|
|
|
|
Human e3 ligase ubr4-kcmf1-calmodulin complex (n-terminal)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606
|
|
|
Chains:
A, B
(1396 residues)
|
|
|
|
|
|
E3 ligase ubr4-kcmf1-calmodulin complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: hek293t. Organism_taxid: 9606
|
|
|
Chains:
A, B, E, F
(1660 residues)
|
|
|
|
|
|
Cryo-em structure of os9-sel1l-hrd1 dimer
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: syvn1, hrd1, kiaa1810. Expressed in: homo sapiens. Expression_system_taxid: 9606. Mus musculus. House mouse. Organism_taxid: 10090.
|
|
|
Chains:
A, B
(265 residues)
|
|
|
|
|
|
Identification of ligands for e3 ligases using fragment-based methods
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: traf4, cart1, mln62, rnf83. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C
(169 residues)
|
|
|
|
|
|
Cryo-em structure of pcmtd1-elobc-cul5-rbx2 (crl5-pcmtd1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pcmtd1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cul5, vacm1. Gene: rnf7, rbx2, roc2, sag. Gene: elob, tceb2.
|
|
|
Chain:
C
(84 residues)
|
|
|
|
|
|
Cryo-em structure of neddylated pcmtd1-elobc-cul5-rbx2 (n8-crl5- pcmtd1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pcmtd1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cul5, vacm1. Mus musculus. Mouse.
|
|
|
Chain:
C
(82 residues)
|
|
|
|
|
|
Gator2 complex bound to arginine sensor castor1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mios. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: wdr24, c16orf21, jfp7. Gene: wdr59, kiaa1923, fp977. Gene: seh1l, sec13l, seh1.
|
|
|
Chains:
C, M
(233 residues)
|
|
|
|
|
|
High-resolution structure of rnf38 ring domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf38. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(79 residues)
|
|
|
|
|
|
Structure of rnf38 ring with linchpin mutant r454y in complex with ubch5b-ub
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: rnf38. Gene: rps27a. Expression_system_taxid: 469008
|
|
|
Chains:
C, D
(69 residues)
|
|
|
|
|
|
Cryo-em structure of the human ubr4/kcmf1/calm1 complex (c-term dimer interface focused refinement)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: calm1, calm, cam, cam1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: ubr4, kiaa0462, kiaa1307, rbaf600. Gene: kcmf1, figc, zzz1. Expression_system_taxid: 7111
|
|
|
Chains:
A, C, B, D
(1036 residues)
|
|
|
|
|
|
Cryo-em structure of the human ubr4/kcmf1/calm1 complex (calm1 focused refinement)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: calm1, calm, cam, cam1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: ubr4, kiaa0462, kiaa1307, rbaf600. Gene: kcmf1, figc, zzz1. Expression_system_taxid: 7111
|
|
|
Chains:
A, C, B, D
(947 residues)
|
|
|
|
|
|
Cryo-em structure of the human ubr4/kcmf1/calm1 complex (n-term focused refinement)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr4, kiaa0462, kiaa1307, rbaf600. Expressed in: trichoplusia ni. Expression_system_taxid: 7111
|
|
|
Chains:
A, B
(1351 residues)
|
|
|
|
|
|
Cryo-em structure of the human ubr4/kcmf1/calm1 complex (c-term focused refinement)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kcmf1, figc, zzz1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: calm1, calm, cam, cam1. Gene: ubr4, kiaa0462, kiaa1307, rbaf600. Expression_system_taxid: 7111
|
|
|
Chains:
D, A, C, B
(43 residues)
|
|
|
|
|
|
Cryo-em structure of thE C. Elegans ubr4/kcmf1 complex (c-term dimer interface focused refinement)
|
|
|
Source: Caenorhabditis elegans. Organism_taxid: 6239. Gene: ubr-4, c44e4.1, cele_c44e4.1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: zk652.6. Expression_system_taxid: 7111
|
|
|
Chains:
C, D
(197 residues)
|
|
|
|
|
|
Structure of the pryspry domain of human mid2, crystal form ii
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mid2, fxy2, rnf60, trim1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A
(165 residues)
|
|
|
|
|
|
The ring domain of idol
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mylip, bzf1, idol, bm-023, pp5242. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(78 residues)
|
|
|
|
|
|
The ring domain of idol
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mylip, bzf1, idol, bm-023, pp5242. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(75 residues)
|
|
|
|
|
|
Cryo-em structure of hrd1-sel1l-xtp3b (state d2) complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: syvn1, hrd1, kiaa1810. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: sel1l, tsa305, unq128/pro1063. Gene: erlec1, c2orf30, xtp3tpb, unq1878/pro4321. Expression_system_taxid: 9606
|
|
|
Chains:
A, B
(266 residues)
|
|
|
|
|
|
Kcmf1 zn-coordinating domains with rtgg peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kcmf1, figc, zzz1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chain:
A
(124 residues)
|
|
|
|
|
|
Ubr box of human ubr1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubr1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(73 residues)
|
|
|
|
|
|
Structure of ubch5b in complex with the u-box domain of the e3 ubiquitin ligase chip
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, pubc1, ubc4, ubc5b, ubch4, ubch5b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Danio rerio. Zebrafish. Organism_taxid: 7955.
|
|
|
Chains:
B, C
(73 residues)
|
|
|
[IntEnz]
[ExPASy]
[KEGG]
