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PDBsum entry 7fyu

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protein ligands links
Lipid binding protein PDB id
7fyu

 

 

 

 

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Contents
Protein chain
133 a.a.
Ligands
SO4 ×2
UUX
Waters ×133
PDB id:
7fyu
Name: Lipid binding protein
Title: Crystal structure of human fabp4 in complex with 2-benzyl-6-tert- butyl-3-methyl-4-phenyl-5-(1h-tetrazol-5-yl)pyridine, i.E. Smiles n1c(=nn=n1)c1c(nc(c(c1c1ccccc1)c)cc1ccccc1)c(c)(c)c with ic50=0.176219 microm
Structure: Fatty acid-binding protein, adipocyte. Chain: a. Synonym: adipocyte lipid-binding protein,albp,adipocyte-type fatty acid-binding protein,a-fabp,afabp,fatty acid-binding protein 4. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fabp4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
1.17Å     R-factor:   0.175     R-free:   0.220
Authors: A.Ehler,J.Benz,U.Obst,B.Buettelmann,M.G.Rudolph
Key ref: U.Obst et al. Crystal structure of a human fabp4 complex. To be published, . PubMed id: 40748031
Date:
27-Apr-23     Release date:   14-Jun-23    
PROCHECK
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 Headers
 References

Protein chain
P15090  (FABP4_HUMAN) -  Fatty acid-binding protein, adipocyte from Homo sapiens
Seq:
Struc:
132 a.a.
133 a.a.
Key:    Secondary structure

 

 

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