PDBsum entry 7ccv

Transferase

PDB id: 7ccv

Contents

Protein chain

274 a.a.

Ligands

PIT

SO4

Waters ×200

PDB id:

7ccv

Name:

Transferase

Title:

Crystal structure of death-associated protein kinase 1 in complex with piceatannol

Structure:

Death-associated protein kinase 1. Chain: a. Synonym: dap kinase 1. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: dapk1, dapk. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.75Å R-factor: 0.175 R-free: 0.208

Authors:

T.Yokoyama,R.Suzuki,M.Mizuguchi

Key ref:

T.Yokoyama et al. (2020). Crystal structure of death-Associated protein kinase complex with the dietary compound resveratrol.. Iucrj, 8, 131.

Date:

18-Jun-20 Release date: 20-Jan-21

Protein chain

P53355  (DAPK1_HUMAN) -  Death-associated protein kinase 1 from Homo sapiens

Seq: 1430 a.a.

Struc: 274 a.a.

Enzyme reactions

• Enzyme class: E.C.2.7.11.1 - non-specific serine/threonine protein kinase.
• Reaction:
  1. L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H⁺
  2. L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site