PDBsum entry 7y27

Structural protein

PDB id: 7y27

Contents

Protein chains

338 a.a.

231 a.a.

230 a.a.

274 a.a.

52 a.a.

12 a.a.

Ligands

CLR

PDB id:

7y27

Name:

Structural protein

Title:

Cryo-em structure of the sst-14-bound sstr2-minigq-scfv16 complex

Structure:

Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: a. Synonym: transducin beta chain 1. Engineered: yes. Engineered guanine nucleotide-binding protein g(q) subunit alpha. Chain: b. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnb1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293.

Authors:

S.Chen,S.Zheng

Key ref:

S.Chen et al. (2023). Molecular basis for the selective g protein signaling somatostatin receptors.. Nat chem biol, 19, 133. PubMed id: 36138141

Date:

09-Jun-22 Release date: 19-Oct-22

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 338 a.a.

Protein chain

No UniProt id for this chain

Struc: 231 a.a.

Protein chain

No UniProt id for this chain

Struc: 230 a.a.

Protein chain

P30874  (SSR2_HUMAN) -  Somatostatin receptor type 2 from Homo sapiens

Seq: 369 a.a.

Struc: 274 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 52 a.a.

Protein chain

No UniProt id for this chain

Struc: 12 a.a.