PDBsum entry 7wu3

Membrane protein

PDB id: 7wu3

Contents

Protein chains

211 a.a.

339 a.a.

56 a.a.

127 a.a.

280 a.a.

Ligands

K6G

PDB id:

7wu3

Name:

Membrane protein

Title:

Cryo-em structure of the adhesion gpcr adgrf1 in complex with minigs

Structure:

Guanine nucleotide-binding protein g(s) subunit alpha isoforms short. Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes.

Source:

Homo sapiens. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Human. Gene: gnb1. Gene: gng2. Lama glama. Organism_taxid: 9844.

Authors:

X.Qu,N.Qiu,M.Wang,Q.Zhao,B.Wu

Key ref:

X.Qu et al. Structural basis of tethered agonism of the adhesion adgrd1 and adgrf1.. Nature, . PubMed id: 35418679

Date:

05-Feb-22 Release date: 27-Apr-22

Protein chain

P63092  (GNAS2_HUMAN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms short from Homo sapiens

Seq: 394 a.a.

Struc: 211 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 339 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 56 a.a.

Protein chain

No UniProt id for this chain

Struc: 127 a.a.

Protein chain

Q5T601  (AGRF1_HUMAN) -  Adhesion G-protein coupled receptor F1 from Homo sapiens

Seq: 910 a.a.

Struc: 280 a.a.

* PDB and UniProt seqs differ at 37 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????