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UniProt functional annotation for Q5T601 | ||
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| UniProt code: Q5T601. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Orphan receptor. |
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| Subcellular location: | |
Cell membrane {ECO:0000269|PubMed:20149256}; Multi-pass membrane protein {ECO:0000255}. |
| Subcellular location: | |
[Isoform 2]: Secreted {ECO:0000269|PubMed:20149256}. |
| Tissue specificity: | |
Mainly expressed in the kidney. Up-regulated in lung adenocarcinomas and prostate cancers. {ECO:0000269|PubMed:20149256}. |
| Ptm: | |
Glycosylated. {ECO:0000269|PubMed:20149256}. |
| Similarity: | |
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. {ECO:0000305}. |
| Sequence caution: | |
Sequence=BAB70874.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAB70874.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305}; Sequence=BAC45260.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI13873.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.