PDBsum entry 7eq1

Structural protein

PDB id: 7eq1

Contents

Protein chains

237 a.a.

284 a.a.

233 a.a.

58 a.a.

338 a.a.

PDB id:

7eq1

Name:

Structural protein

Title:

Gpr114-gs-scfv16 complex

Structure:

Gs protein alpha subunit. Chain: a. Engineered: yes. Adhesion g-protein coupled receptor g5. Chain: r. Synonym: gpr114, gpr114g-protein coupled receptor 114,g-protein coupled receptor pgr27. Engineered: yes. Scfv16.

Source:

Bos taurus. Bovine. Organism_taxid: 9913. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Homo sapiens. Human. Organism_taxid: 9606. Gene: adgrg5, gpr114, pgr27, unq2524/pro6017.

Authors:

Y.Ping

Key ref:

Y.Q.Ping et al. (2022). Structural basis for the tethered peptide activation adhesion gpcrs.. Nature, 604, 763. PubMed id: 35418678

Date:

28-Apr-21 Release date: 11-May-22

Protein chain

P04896  (GNAS2_BOVIN) -  Guanine nucleotide-binding protein G(s) subunit alpha isoforms short from Bos taurus

Seq: 394 a.a.

Struc: 237 a.a.*

Protein chain

P63097  (GNAI1_BOVIN) -  Guanine nucleotide-binding protein G(i) subunit alpha-1 from Bos taurus

Seq: 354 a.a.

Struc: 237 a.a.*

Protein chain

Q8IZF4  (AGRG5_HUMAN) -  Adhesion G-protein coupled receptor G5 from Homo sapiens

Seq: 528 a.a.

Struc: 284 a.a.

Protein chain

No UniProt id for this chain

Struc: 233 a.a.

Protein chain

P63212  (GBG2_BOVIN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Bos taurus

Seq: 71 a.a.

Struc: 58 a.a.

Protein chain

P54311  (GBB1_RAT) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Rattus norvegicus

Seq: 340 a.a.

Struc: 338 a.a.

* PDB and UniProt seqs differ at 220 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????