PDBsum entry 7ejk

Membrane protein

PDB id: 7ejk

Contents

Protein chains

215 a.a.

334 a.a.

54 a.a.

233 a.a.

257 a.a.

Ligands

J5C

PDB id:

7ejk

Name:

Membrane protein

Title:

Structure of the alpha2a-adrenergic receptor goa signaling complex bound to oxymetazoline

Structure:

Guanine nucleotide-binding protein g(o) subunit alpha. Chain: a. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1. Chain: b. Synonym: transducin beta chain 1. Engineered: yes. Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gnao1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: gnb1. Gene: gng2. Mus musculus.

Authors:

J.Xu,S.Cao,Z.Liu,Y.Du

Key ref:

J.Xu et al. Structure of alpha2a-Adrenergic receptor goa signalin complex. To be published, . PubMed id: 35245122

Date:

02-Apr-21 Release date: 13-Apr-22

Protein chain

P09471  (GNAO_HUMAN) -  Guanine nucleotide-binding protein G(o) subunit alpha from Homo sapiens

Seq: 354 a.a.

Struc: 215 a.a.

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 334 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 54 a.a.

Protein chain

No UniProt id for this chain

Struc: 233 a.a.

Protein chain

P08913  (ADA2A_HUMAN) -  Alpha-2A adrenergic receptor from Homo sapiens

Seq: 465 a.a.

Struc: 257 a.a.

Enzyme reactions

• Enzyme class: Chain A: E.C.3.6.5.- - ?????