PDBsum entry 4xck

Transferase

PDB id: 4xck

Contents

Protein chains

306 a.a.

Ligands

RIB ×2

ADP ×5

Metals

_CS ×4

Waters ×248

PDB id:

4xck

Name:

Transferase

Title:

Vibrio cholerae o395 ribokinase complexed with adp, ribose and cesium ion.

Structure:

Ribokinase. Chain: a, b, c, d. Engineered: yes

Source:

Vibrio cholerae serotype o1 (strain atcc 39541 / classical ogawa 395 / o395). Organism_taxid: 345073. Strain: atcc 39541 / classical ogawa 395 / o395. Atcc: 39541. Gene: rbsk, vc0395_0007, vc395_a0124. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.37Å R-factor: 0.191 R-free: 0.251

Authors:

R.Paul,M.D.Patra,U.Sen

Key ref:

R.Paul et al. (2015). Crystal structure of apo and ligand bound vibrio cholerae ribokinase (Vc-RK): role of monovalent cation induced activation and structural flexibility in sugar phosphorylation. Adv Exp Med Biol, 842, 293-307. PubMed id: 25408351 DOI: 10.1007/978-3-319-11280-0_19

Date:

18-Dec-14 Release date: 21-Jan-15

Protein chains

A0A0H2UL04  (A0A0H2UL04_VIBC3) -  Ribokinase from Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)

Seq: 309 a.a.

Struc: 306 a.a.

Enzyme reactions

• Enzyme class: E.C.2.7.1.15 - ribokinase.
• Reaction: D-ribose + ATP = D-ribose 5-phosphate + ADP + H⁺

D-ribose + ATP (Bound ligand (Het Group name = RIB) corresponds exactly) = D-ribose 5-phosphate (Bound ligand (Het Group name = ADP) corresponds exactly) + ADP + H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

DOI no: 10.1007/978-3-319-11280-0_19

Adv Exp Med Biol 842:293-307 (2015)

PubMed id: 25408351

Crystal structure of apo and ligand bound vibrio cholerae ribokinase (Vc-RK): role of monovalent cation induced activation and structural flexibility in sugar phosphorylation.

R.Paul, M.D.Patra, U.Sen.

ABSTRACT

No abstract given.