PDBsum entry 4uhd

Hydrolase

PDB id: 4uhd

Contents

Protein chain

274 a.a.

Ligands

ACT ×2

PEG ×2

Metals

_CL

_MG

Waters ×366

PDB id:

4uhd

Name:

Hydrolase

Title:

Structural studies of a thermophilic esterase from thermogutta terrifontis (acetate bound)

Structure:

Esterase. Chain: a. Engineered: yes

Source:

Planctomycetes bacterium r1. Organism_taxid: 1331910. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.07Å R-factor: 0.094 R-free: 0.112

Authors:

C.Sayer,M.N.Isupov,E.Bonch-Osmolovskaya,J.A.Littlechild

Key ref:

C.Sayer et al. (2015). Structural studies of a thermophilic esterase from a new Planctomycetes species, Thermogutta terrifontis. Febs J, 282, 2846-2857. PubMed id: 26011036 DOI: 10.1111/febs.13326

Date:

24-Mar-15 Release date: 10-Jun-15

Protein chain

A0A0M3KKY6  (A0A0M3KKY6_9BACT) -  Esterase from Thermogutta terrifontis

Seq: 282 a.a.

Struc: 274 a.a.

Enzyme reactions

• Enzyme class: E.C.3.1.1.1 - carboxylesterase.
• Reaction: a carboxylic ester + H2O = an alcohol + a carboxylate + H⁺

carboxylic ester + H2O = alcohol (Bound ligand (Het Group name = ACT) matches with 60.00% similarity) + carboxylate + H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

DOI no: 10.1111/febs.13326

Febs J 282:2846-2857 (2015)

PubMed id: 26011036

Structural studies of a thermophilic esterase from a new Planctomycetes species, Thermogutta terrifontis.

C.Sayer, M.N.Isupov, E.Bonch-Osmolovskaya, J.A.Littlechild.

ABSTRACT

No abstract given.