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PDBsum entry 3n0c

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Top Page protein ligands Protein-protein interface(s) links
Transferase PDB id
3n0c
Contents
Protein chains
216 a.a.
Ligands
UMP ×4
FAD ×4
Waters ×46

References listed in PDB file
Key reference
Title Diffraction study of protein crystals grown in cryoloops and micromounts.
Authors M.A.Berger, J.H.Decker, I.I.Mathews.
Ref. J Appl Crystallogr, 2010, 43, 1513-1518.
PubMed id 22477781
Abstract
No abstract given.
Secondary reference #1
Title Functional analysis of substrate and cofactor complex structures of a thymidylate synthase-Complementing protein.
Authors I.I.Mathews, A.M.Deacon, J.M.Canaves, D.Mcmullan, S.A.Lesley, S.Agarwalla, P.Kuhn.
Ref. Structure, 2003, 11, 677-690. [DOI no: 10.1016/S0969-2126(03)00097-2]
PubMed id 12791256
Full text Abstract
Figure 2.
Figure 2. Structure of TM0449(A) View of the monomer.(B) Topology diagram of the monomer (Westhead et al., 1998). b strands, filled black triangles; a helices, filled blue circles. Strand directions are indicated using upward-pointing or downward-pointing triangles. N and C termini are labeled.(C) View of the monomer orthogonal to the view in (A).(D) View of the tetramer showing bound FAD molecules. Flavin ring exposed to the surface in one of the monomers is shown with an arrow.(E) Orthogonal view of the tetramer. The paired FAD molecules on each side of the tetramer, cyan and black.
The above figure is reproduced from the cited reference with permission from Cell Press
PROCHECK
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