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PDBsum entry 3b0c

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protein ligands Protein-protein interface(s) links
DNA binding protein PDB id
3b0c

 

 

 

 

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Contents
Protein chains
91 a.a.
73 a.a.
Ligands
CIT ×3
Waters ×52
PDB id:
3b0c
Name: DNA binding protein
Title: Crystal structure of the chicken cenp-t histone fold/cenp-w complex, crystal form i
Structure: Centromere protein t. Chain: t. Synonym: cenp-t. Engineered: yes. Centromere protein w. Chain: w. Synonym: cenp-w. Engineered: yes
Source: Gallus gallus. Chickens. Organism_taxid: 9031. Gene: cenpt. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cenp-w.
Resolution:
2.20Å     R-factor:   0.229     R-free:   0.269
Authors: T.Nishino,K.Takeuchi,K.E.Gascoigne,A.Suzuki,T.Hori,T.Oyama, K.Morikawa,I.M.Cheeseman,T.Fukagawa
Key ref: T.Nishino et al. (2012). CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. Cell, 148, 487-501. PubMed id: 22304917
Date:
08-Jun-11     Release date:   07-Mar-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
F1NPG5  (CENPT_CHICK) -  Centromere protein T from Gallus gallus
Seq:
Struc:
 
Seq:
Struc:
639 a.a.
91 a.a.
Protein chain
Pfam   ArchSchema ?
P0DJH6  (CENPW_CHICK) -  Centromere protein W from Gallus gallus
Seq:
Struc:
76 a.a.
73 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: Chains T, W: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
Cell 148:487-501 (2012)
PubMed id: 22304917  
 
 
CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold.
T.Nishino, K.Takeuchi, K.E.Gascoigne, A.Suzuki, T.Hori, T.Oyama, K.Morikawa, I.M.Cheeseman, T.Fukagawa.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
22561346 A.Schleiffer, M.Maier, G.Litos, F.Lampert, P.Hornung, K.Mechtler, and S.Westermann (2012).
CENP-T proteins are conserved centromere receptors of the Ndc80 complex.
  Nat Cell Biol, 14, 604-613.  
22561349 K.E.Gascoigne, and I.M.Cheeseman (2012).
T time for point centromeres.
  Nat Cell Biol, 14, 559-561.  
22561345 L.J.Bock, C.Pagliuca, N.Kobayashi, R.A.Grove, Y.Oku, K.Shrestha, C.Alfieri, C.Golfieri, A.Oldani, M.Dal Maschio, R.Bermejo, T.R.Hazbun, T.U.Tanaka, and P.De Wulf (2012).
Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore.
  Nat Cell Biol, 14, 614-624.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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