PDBsum entry 2qhf

Lyase

PDB id: 2qhf

Contents

Protein chain

392 a.a. *

Ligands

ACT ×12

NCA

TRS

Metals

_NA ×2

_CL

Waters ×473

* Residue conservation analysis

PDB id:

2qhf

Name:

Lyase

Title:

Mycobacterium tuberculosis chorismate synthase in complex with nca

Structure:

Chorismate synthase. Chain: a. Synonym: 5-enolpyruvylshikimate-3-phosphate phospholyase. Engineered: yes

Source:

Mycobacterium tuberculosis. Strain: h37rv. Gene: aroc, arof. Expressed in: escherichia coli.

Resolution:

1.65Å R-factor: 0.165 R-free: 0.186

Authors:

M.Bruning,G.P.Bourenkov,N.I.Strizhov,H.D.Bartunik

Key ref:

M.Bruning et al. Mycobacterium tuberculosis chorismate synthase in complex with nca. To be published, .

Date:

02-Jul-07 Release date: 15-Jul-08

Protein chain

P9WPY1  (AROC_MYCTU) -  Chorismate synthase from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Seq: 401 a.a.

Struc: 392 a.a.

Enzyme reactions

• Enzyme class: E.C.4.2.3.5 - chorismate synthase.
• Pathway: Shikimate and Chorismate Biosynthesis
• Reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate
• Cofactor: FMN

Molecule diagrams generated from .mol files obtained from the KEGG ftp site