 |
PDBsum entry 210d
 |
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
| |
|
DOI no:
|
Biochemistry
34:15487-15495
(1995)
|
|
PubMed id:
|
|
|
|
|
|
| |
|
Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative.
|
|
G.N.Parkinson,
G.M.Arvanitis,
L.Lessinger,
S.L.Ginell,
R.Jones,
B.Gaffney,
H.M.Berman.
|
|
|
|
|
| |
ABSTRACT
|
|
|
|
| |
|
|
The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was
determined to atomic (1.35 A) resolution by single isomorphous replacement. The
d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous
with other DNA hexanucleotides. Despite completely different crystal packing,
the essential characteristics of the Z-DNA conformation are maintained. The
structure was determined by single isomorphous replacement using a triammine
platinum fragment. Thus, this study also demonstrates, for the first time, the
feasibility of the use of this reagent for the direct phasing of DNA crystal
structures.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
 |
 |
|
Literature references that cite this PDB file's key reference
|
|
|
| |
PubMed id
|
|
Reference
|
|
|
|
|
|
S.Komeda,
T.Moulaei,
M.Chikuma,
A.Odani,
R.Kipping,
N.P.Farrell,
and
L.D.Williams
(2011).
The phosphate clamp: a small and independent motif for nucleic acid backbone recognition.
|
| |
Nucleic Acids Res,
39,
325-336.
|
|
|
|
|
|
|
J.B.Mangrum,
and
N.P.Farrell
(2010).
Excursions in polynuclear platinum DNA binding.
|
| |
Chem Commun (Camb),
46,
6640-6650.
|
|
|
|
|
|
|
O.Bradác,
T.Zimmermann,
and
J.V.Burda
(2008).
Comparison of the electronic properties, and thermodynamic and kinetic parameters of the aquation of selected platinum(II) derivatives with their anticancer IC50 indexes.
|
| |
J Mol Model,
14,
705-716.
|
|
|
|
|
|
|
M.Pavelka,
and
J.V.Burda
(2007).
Pt-bridges in various single-strand and double-helix DNA sequences. DFT and MP2 study of the cisplatin coordination with guanine, adenine, and cytosine.
|
| |
J Mol Model,
13,
367-379.
|
|
|
|
|
|
|
S.Thiyagarajan,
S.S.Rajan,
and
N.Gautham
(2005).
Structure of d(TGCGCG).d(CGCGCA) in two crystal forms: effect of sequence and crystal packing in Z-DNA.
|
| |
Acta Crystallogr D Biol Crystallogr,
61,
1125-1131.
|
|
|
|
|
|
|
M.Boczkowska,
P.Guga,
B.Karwowski,
and
A.Maciaszek
(2000).
Effect of P-chirality of internucleotide bonds on B-Z conversion of stereodefined self-complementary phosphorothioate oligonucleotides of the [PS]-d(CG)4 and [PS]-d(GC)4 series.
|
| |
Biochemistry,
39,
11057-11064.
|
|
|
|
|
|
|
A.Harper,
J.A.Brannigan,
M.Buck,
L.Hewitt,
R.J.Lewis,
M.H.Moore,
and
B.Schneider
(1998).
Structure of d(TGCGCA)2 and a comparison to other DNA hexamers.
|
| |
Acta Crystallogr D Biol Crystallogr,
54,
1273-1284.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
B.Schneider,
K.Patel,
and
H.M.Berman
(1998).
Hydration of the phosphate group in double-helical DNA.
|
| |
Biophys J,
75,
2422-2434.
|
|
|
|
|
|
|
L.Malinina,
V.Tereshko,
E.Ivanova,
J.A.Subirana,
V.Zarytova,
and
Y.Nekrasov
(1998).
Structural variability and new intermolecular interactions of Z-DNA in crystals of d(pCpGpCpGpCpG).
|
| |
Biophys J,
74,
2482-2490.
|
|
|
PDB codes:
|
|
|
|
|
|
|
The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
codes are
shown on the right.
|
|
Links
