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PDBsum entry 210d
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References listed in PDB file
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Key reference
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Title
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Crystal and molecular structure of a new z-Dna crystal form: d[cgt(2-Nh2-A)cg] and its platinated derivative.
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Authors
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G.N.Parkinson,
G.M.Arvanitis,
L.Lessinger,
S.L.Ginell,
R.Jones,
B.Gaffney,
H.M.Berman.
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Ref.
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Biochemistry, 1995,
34,
15487-15495.
[DOI no: ]
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PubMed id
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Abstract
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The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was
determined to atomic (1.35 A) resolution by single isomorphous replacement. The
d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous
with other DNA hexanucleotides. Despite completely different crystal packing,
the essential characteristics of the Z-DNA conformation are maintained. The
structure was determined by single isomorphous replacement using a triammine
platinum fragment. Thus, this study also demonstrates, for the first time, the
feasibility of the use of this reagent for the direct phasing of DNA crystal
structures.
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Headers
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