PDBsum entry 1ydh

Structural genomics, unknown function

PDB id: 1ydh

Contents

Protein chains

184 a.a. *

Ligands

NO3

EDO ×4

Waters ×319

* Residue conservation analysis

PDB id:

1ydh

Name:

Structural genomics, unknown function

Title:

X-ray structure of a lysine decarboxylase-like protein from arabidopsis thaliana gene at5g11950

Structure:

At5g11950. Chain: a, b. Engineered: yes

Source:

Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: at5g11950. Expressed in: escherichia coli. Expression_system_taxid: 562.

Biol. unit:

Dimer (from PQS)

Resolution:

2.15Å R-factor: 0.162 R-free: 0.213

Authors:

G.E.Wesenberg,G.N.Phillips Jr.,E.Bitto,C.A.Bingman,S.T.M.Allard, Center For Eukaryotic Structural Genomics (Cesg)

Key ref:

W.B.Jeon et al. (2006). X-ray crystal structures of the conserved hypothetical proteins from Arabidopsis thaliana gene loci At5g11950 and AT2g37210. Proteins, 65, 1051-1054. PubMed id: 17048257 DOI: 10.1002/prot.21166

Date:

23-Dec-04 Release date: 11-Jan-05

Protein chains

Q84MC2  (LOG8_ARATH) -  Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG8 from Arabidopsis thaliana

Seq: 216 a.a.

Struc: 184 a.a.

Enzyme reactions

• Enzyme class: E.C.3.2.2.n1 - ?????

DOI no: 10.1002/prot.21166

Proteins 65:1051-1054 (2006)

PubMed id: 17048257

X-ray crystal structures of the conserved hypothetical proteins from Arabidopsis thaliana gene loci At5g11950 and AT2g37210.

W.B.Jeon, S.T.Allard, C.A.Bingman, E.Bitto, B.W.Han, G.E.Wesenberg, G.N.Phillips.

ABSTRACT

No abstract given.

Selected figure(s)

Figure 1.
Figure 1. (A) Ribbon diagram of the At5g11950 dimer with each monomer colored separately. (B) An overlay of C traces of At5g11950 (red) and At2g37210 (cyan). The residues corresponding to helix 3 and neighboring loops adopt a defined structure within At5g11950 (red). The same region is disordered in the At2g37210 structure (cyan). A fully conserved residue, Arg98, and the PGGxGTxxE motif, which is highly conserved among the LDC like proteins,[15] were mapped onto a C trace of the At5g11950 structure. (C) Surface view of the two monomers (yellow and cyan) in the At2g37210 dimer. The dark blue area represents the conserved motif PGGxGTxxE and residue Arg98, located at the bottom of a cavity. The red line highlights the residues corresponding to helix 3 of At5g11950. These residues are positioned near the entrance to the cavity and are disordered in the crystal structure of At2g37210, suggesting that they may be involved in controlling access of a substrate to the putative active site.

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2006, 65, 1051-1054) copyright 2006.