Ligand clusters for UniProt code Q9Y657

Ligand clusters for Q9Y657: Spindlin-1 from Homo sapiens

		Top 6 (of 14) ligand clusters Cluster 1. 20 ligand types 26 ligands Cluster 2. 1 ligand type 1 ligand Cluster 3. 5 ligand types 7 ligands Cluster 4. 2 ligand types 2 ligands Cluster 5. 1 ligand type 1 ligand Cluster 6. 1 ligand type 1 ligand
Representative protein: 5y5wA

Structures

PDB		Schematic diagram
5y5wA
5y5wC
4mzfB
4mzgB
4mzhA
		more ...

Cluster 1 contains 20 ligand types

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: DMS × 3 dimethyl sulfoxide Dimethyl sulfoxide PDB codes: 6i8b(B), 6qpl(B).
		2. Ligand: 2OD × 2 5'-Methoxy-6'-[3-(Pyrrolidin-1-Yl) propoxy]spiro[cyclobutane-1,3'-Indol]-2'-Amine PDB codes: 6i8y(A),
		3. Ligand: ARG-HIS-ARG-M3L-VAL × 2 M3L=N-Trimethyllysine. PDB codes: 5y5w(A),
		4. Ligand: MPD × 2 (4s)-2-Methyl-2,4-Pentanediol PDB codes: 6i8y(A), 6qpl(B).
		5. Ligand: MRD × 2 (4r)-2-Methylpentane-2,4-Diol PDB codes: 4mzg(B), 6i8l(B).
		6. Ligand: 6P9 × 1 [2-(Phenylamino)-1,4-Phenylene]bis({4-[2-(Pyrrolidin-1- Yl)ethyl]piperidin-1-Yl}methanone) PDB code: 5jsg(A).
		7. Ligand: 6PD × 1 [4-(2-Pyrrolidin-1-Ylethyl)piperidin-1-Yl]-[4-[4-(2- Pyrrolidin-1-Ylethyl)piperidin-1-Yl]carbonyl- 3-[[4- (Pyrrolidin-1-Ylmethoxy)phenyl]amino]phenyl]methanone PDB code: 5jsj(A).
		8. Ligand: ALA-ARG-THR-M3L-GLN-THR-ALA × 1 M3L=N-Trimethyllysine. PDB code: 4mzh(A).
		9. Ligand: ALA-ARG-THR-M3L-GLN-THR-ALA-ARG × 1 M3L=N-Trimethyllysine. PDB code: 4h75(A).
		10. Ligand: ALA-ARG-THR-M3L-GLN-THR-ALA-ARG-LYS × 1 M3L=N-Trimethyllysine. PDB code: 4mzg(B).
		11. Ligand: ALA-ARG-THR-M3L-GLN-THR-ALA-ARG-M3L-SER × 1 M3L=N-Trimethyllysine. PDB code: 7bqz(E).
		12. Ligand: ALA-ARG-THR-M3L-GLN-THR-ALA-ARG-MLY × 1 M3L=N-Trimethyllysine, MLY=N-Dimethyl-Lysine. PDB code: 7bu9(A).
		13. Ligand: ALA-ARG-THR-M3L-GLN-THR-ALA-DA2-LYS × 1 M3L=N-Trimethyllysine, DA2=Ng,Ng-Dimethyl-L-Arginine. PDB code: 4mzf(B).
		14. Ligand: EDO × 1 1,2-Ethanediol PDB code: 6i8y(A).
		15. Ligand: H7Q × 1 5'-(Cyclopropylmethoxy)-6'-[3-(1,3-Dihydroisoindol-2- Yl)propoxy]spiro[cyclopentane-1,3'-Indole]- 2'-Amine PDB code: 6i8l(B).
		16. Ligand: H7T × 1 2-[4-[2-[[2-[3-[2-Azanyl-5-(Cyclopropylmethoxy)-3,3- Dimethyl-Indol-6-Yl]oxypropyl]-1,3- Dihydroisoindol-5- Yl]oxy]ethyl]-1,2,3-Triazol-1-Yl]-1-[4-(2-Pyrrolidin- 1-Ylethyl)piperidin-1- Yl]ethanone PDB code: 6i8b(B).
		17. Ligand: HIS-ARG-M3L-VAL × 1 M3L=N-Trimethyllysine. PDB code: 5y5w(B).
		18. Ligand: JC5 × 1 [3-(Aminomethyl)-5-[3-(1,3-Dihydroisoindol-2-Yl) propoxy]-4-Methoxy-Phenyl]methanamine PDB code: 6qpl(B).
		19. Ligand: NHE × 1 2-[N-Cyclohexylamino]ethane sulfonic acid PDB code: 4h75(A).
		20. Ligand: SO4 × 1 Sulfate ion PDB code: 4h75(A).
+ more. Press for full list

Cluster 2 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: H7T × 1 2-[4-[2-[[2-[3-[2-Azanyl-5-(Cyclopropylmethoxy)-3,3- Dimethyl-Indol-6-Yl]oxypropyl]-1,3- Dihydroisoindol-5- Yl]oxy]ethyl]-1,2,3-Triazol-1-Yl]-1-[4-(2-Pyrrolidin- 1-Ylethyl)piperidin-1- Yl]ethanone PDB code: 6i8b(B).

Cluster 3 contains 5 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: DMS × 1 dimethyl sulfoxide Dimethyl sulfoxide PDB code: 6i8b(B).
		2. Ligand: GLY × 1 glycine PDB code: 6i8b(B).
		3. Ligand: GOL × 1 glycerin Glycerol PDB code: 6i8y(A).
		4. Ligand: MPD × 3 (4s)-2-Methyl-2,4-Pentanediol PDB codes: 4mzg(B), 6i8l(B), 6qpl(B).
		5. Ligand: BAM × 1 Benzamidine PDB code: 7cna(A).

Cluster 4 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 4h75(A).
		2. Ligand: PO4 × 1 Phosphate ion PDB code: 2ns2(A).

Cluster 5 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: BAM × 1 Benzamidine PDB code: 7cna(A).

Cluster 6 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 6qpl(B).