Ligand clusters for UniProt code Q9H1D0

Ligand clusters for Q9H1D0: Transient receptor potential cation channel subfamily V member 6 from Homo sapiens

		Top 6 (of 8) ligand clusters Cluster 1. 8 ligand types 20 ligands Cluster 2. 7 ligand types 12 ligands Cluster 3. 4 ligand types 4 ligands Cluster 4. 2 ligand types 8 ligands Cluster 5. 1 ligand type 4 ligands Cluster 6. 1 ligand type 2 ligands
Representative protein: 7k4eA

Structures

PDB		Schematic diagram
7k4eA
7k4bA
6d7tA
7k4fA
7k4aA
		more ...

Cluster 1 contains 8 ligand types

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Ligand		Description
		1. Ligand: PCW × 11 1,2-Dioleoyl-Sn-Glycero-3-Phosphocholine PDB codes: 7k4a(A), 7k4b(A),
		2. Ligand: Y01 × 3 Cholesterol hemisuccinate PDB codes: 7k4a(A), 7k4b(A).
		3. Ligand: 5GK × 1 5-[(4-{Cis-4-[3-(Trifluoromethyl) phenyl]cyclohexyl}piperazin-1-Yl)methyl]pyridin-2(1h)- One PDB code: 7k4f(A).
		4. Ligand: 81F × 1 1-(5-Bromopyridin-3-Yl)-4-[Cis-4-(3-Methylphenyl) cyclohexyl]piperazine PDB code: 7k4c(A).
		5. Ligand: FZ4 × 1 2-Aminoethyl diphenylborinate PDB code: 6d7t(A).
		6. Ligand: VUG × 1 1-[Cis-4-(3-Methylphenyl)cyclohexyl]-4-(Pyridin-3-Yl) piperazine PDB code: 7k4b(A).
		7. Ligand: VUJ × 1 5-({4-[(1r,4s)-3'-Methyl[1,2,3,4-Tetrahydro[1,1'- Biphenyl]]-4-Yl]piperazin-1-Yl}methyl)pyridin- 2(1h)- One PDB code: 7k4e(A).
		8. Ligand: VUM × 1 5-[(4-{Trans-4-Hydroxy-4-[3-(Trifluoromethyl) phenyl]cyclohexyl}piperazin-1-Yl)methyl]pyridin- 2(1h)- One PDB code: 7k4d(A).

Cluster 2 contains 7 ligand types

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Ligand		Description
		1. Ligand: PCW × 4 1,2-Dioleoyl-Sn-Glycero-3-Phosphocholine PDB codes: 7k4a(A), 7k4b(A),
		2. Ligand: Y01 × 3 Cholesterol hemisuccinate PDB codes: 7k4a(A), 7k4b(A).
		3. Ligand: 5GK × 1 5-[(4-{Cis-4-[3-(Trifluoromethyl) phenyl]cyclohexyl}piperazin-1-Yl)methyl]pyridin-2(1h)- One PDB code: 7k4f(A).
		4. Ligand: 81F × 1 1-(5-Bromopyridin-3-Yl)-4-[Cis-4-(3-Methylphenyl) cyclohexyl]piperazine PDB code: 7k4c(A).
		5. Ligand: VUG × 1 1-[Cis-4-(3-Methylphenyl)cyclohexyl]-4-(Pyridin-3-Yl) piperazine PDB code: 7k4b(A).
		6. Ligand: VUJ × 1 5-({4-[(1r,4s)-3'-Methyl[1,2,3,4-Tetrahydro[1,1'- Biphenyl]]-4-Yl]piperazin-1-Yl}methyl)pyridin- 2(1h)- One PDB code: 7k4e(A).
		7. Ligand: VUM × 1 5-[(4-{Trans-4-Hydroxy-4-[3-(Trifluoromethyl) phenyl]cyclohexyl}piperazin-1-Yl)methyl]pyridin- 2(1h)- One PDB code: 7k4d(A).

Cluster 3 contains 4 ligand types

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Ligand		Description
		1. Ligand: 5GK × 1 5-[(4-{Cis-4-[3-(Trifluoromethyl) phenyl]cyclohexyl}piperazin-1-Yl)methyl]pyridin-2(1h)- One PDB code: 7k4f(A).
		2. Ligand: 81F × 1 1-(5-Bromopyridin-3-Yl)-4-[Cis-4-(3-Methylphenyl) cyclohexyl]piperazine PDB code: 7k4c(A).
		3. Ligand: VUG × 1 1-[Cis-4-(3-Methylphenyl)cyclohexyl]-4-(Pyridin-3-Yl) piperazine PDB code: 7k4b(A).
		4. Ligand: VUM × 1 5-[(4-{Trans-4-Hydroxy-4-[3-(Trifluoromethyl) phenyl]cyclohexyl}piperazin-1-Yl)methyl]pyridin- 2(1h)- One PDB code: 7k4d(A).

Cluster 4 contains 2 ligand types

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Ligand		Description
		1. Ligand: PCW × 6 1,2-Dioleoyl-Sn-Glycero-3-Phosphocholine PDB codes: 7k4a(A), 7k4b(A),
		2. Ligand: Y01 × 2 Cholesterol hemisuccinate PDB codes: 7k4a(A), 7k4b(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: PCW × 4 1,2-Dioleoyl-Sn-Glycero-3-Phosphocholine PDB codes: 7k4a(A), 7k4b(A),

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: PCW × 2 1,2-Dioleoyl-Sn-Glycero-3-Phosphocholine PDB codes: 7k4a(A), 7k4b(A).