Ligand clusters for UniProt code P78536

Ligand clusters for P78536: Disintegrin and metalloproteinase domain-containing protein 17 from Homo sapiens

		4 ligand clusters Cluster 1. 13 ligand types 44 ligands Cluster 2. 1 ligand type 1 ligand Cluster 3. 1 ligand type 5 ligands Cluster 4. 3 ligand types 4 ligands
Representative protein: 2oi0A

Structures

PDB		Schematic diagram
2oi0A
3ckiA
2a8hA
1bkcA
3l0vA
		more ...

Cluster 1 contains 13 ligand types

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Ligand		Description
_Zn		1. Metal: _ZN × 22 PDB codes: 1bkc(A), 1zxc(A), 2a8h(A), 2ddf(A), 2fv5(A), 2fv9(A), 2i47(A), 2oi0(A), 3b92(A), 3cki(A), 3e8r(A), 3edz(A), 3ewj(A), 3g42(A), 3kmc(A), 3kme(A), 3l0t(A), 3l0v(A), 3le9(A), 3lea(A), 3lgp(A), 3o64(A).
		2. Ligand: INN × 11 N-{(2r)-2-[2-(Hydroxyamino)-2-Oxoethyl]-4- Methylpentanoyl}-3-Methyl-L-Valyl-N-(2-Aminoethyl)-L- Alaninamide PDB codes: 1bkc(A), 2ddf(A), 2fv9(A), 2i47(A), 3e8r(A), 3edz(A), 3ewj(A), 3kmc(A), 3kme(A), 3l0t(A), 3o64(A).
		3. Ligand: 283 × 1 (3s)-1-{[4-(But-2-Yn-1-Yloxy) phenyl]sulfonyl}pyrrolidine-3-Thiol PDB code: 2oi0(A).
		4. Ligand: 440 × 1 3-{[4-(But-2-Yn-1-Yloxy)phenyl]sulfonyl}propane-1- Thiol PDB code: 3b92(A).
		5. Ligand: 4NH × 1 4-({4-[(4-Aminobut-2-Ynyl)oxy]phenyl}sulfonyl)-N- Hydroxy-2,2-Dimethylthiomorpholine-3-Carboxamide PDB code: 2a8h(A).
		6. Ligand: 50X × 1 (2r,3r)-4-[(2r)-2-(3-Chlorophenyl)pyrrolidin-1-Yl]-2,3- Dihydroxy-4-Oxo-N-[(5-{[2- (Trifluoromethyl)-1h- Benzimidazol-1-Yl]methyl}thiophen-2-Yl) methyl]butanamide PDB code: 3lgp(A).
		7. Ligand: 541 × 1 (2r)-N-Hydroxy-2-[(3s)-3-Methyl-3-{4-[(2- Methylquinolin-4-Yl)methoxy]phenyl}-2-Oxopyrrolidin-1- Yl]propanamide PDB code: 2fv5(A).
		8. Ligand: 615 × 1 (1r,2s)-N~2~-Hydroxy-1-{4-[(2-Phenylquinolin-4-Yl) methoxy]benzyl}cyclopropane-1,2-Dicarboxamide PDB code: 3e8r(A).
		9. Ligand: 724 × 1 (5r)-5-[(5-Methoxy-3-Oxo-1,3-Dihydro-2h-Indazol-2-Yl) methyl]-5-Methylimidazolidine-2,4-Dione PDB code: 3l0v(A).
		10. Ligand: 727 × 1 (5r)-5-[(5-Methoxy-3-Oxo-1,3-Dihydro-2h-Indazol-2-Yl) methyl]-5-Phenylimidazolidine-2,4-Dione PDB code: 3le9(A).
		11. Ligand: 792 × 1 N-{[4-(But-2-Yn-1-Yloxy)phenyl]sulfonyl}-5-Methyl-D- Tryptophan PDB code: 3g42(A).
		12. Ligand: IH6 × 1 (3s)-4-{[4-(But-2-Ynyloxy)phenyl]sulfonyl}-N-Hydroxy- 2,2-Dimethylthiomorpholine-3-Carboxamide PDB code: 1zxc(A).
		13. Ligand: Z93 × 1 2-{[(4r)-2,5-Dioxo-4-(4-Pyridin-3-Ylphenyl) imidazolidin-4-Yl]methyl}-6-Methoxy-1-Oxo-1h- Isoindolium PDB code: 3lea(A).

Cluster 2 contains 1 ligand type

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Ligand		Description
		1. Ligand: CIT × 1 citric acid Citric acid PDB code: 3edz(A).

Cluster 3 contains 1 ligand type

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Ligand		Description
		1. Ligand: IPA × 5 isopropyl alcohol Isopropyl alcohol PDB codes: 2ddf(A), 3kme(A), 3l0t(A), 3le9(A), 3o64(A).

Cluster 4 contains 3 ligand types

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Ligand		Description
_Zn		1. Metal: _ZN × 1 PDB code: 3b92(A).
_Ca		2. Metal: _CA × 2 PDB codes: 2ddf(A), 3o64(A).
_Na		3. Metal: _NA × 1 PDB code: 3cki(A).