Ligand clusters for UniProt code P63073

Ligand clusters for P63073: Eukaryotic translation initiation factor 4E from Mus musculus

		3 ligand clusters Cluster 1. 16 ligand types 35 ligands Cluster 2. 1 ligand type 11 ligands Cluster 3. 1 ligand type 3 ligands
Representative protein: 1ej1B

Structures

PDB		Schematic diagram
1ej1B
1l8bB
1l8bA
6ylvA
6u09A
		more ...

Cluster 1 contains 16 ligand types

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: M7G × 5 7n-Methyl-8-Hydroguanosine-5'-Diphosphate PDB codes: 1ej1(A), 1ej4(A), 1ejh(A),
		2. Ligand: MGP × 5 7-Methyl-Guanosine-5'-Triphosphate PDB codes: 1l8b(A), 5bxv(A), 6gkj(A),
		3. Ligand: WZO × 5 [(2~{r},3~{r},4~{r},5~{r})-5-(2-Azanyl-7-Methyl-6- Oxidanylidene-1~{h}-Purin-7-Ium-9-Yl)-4-Methoxy- 3- Oxidanyl-Oxolan-2-Yl]methyl [phosphonooxy(sulfanyl) phosphoryl] hydrogen phosphate PDB codes: 5m7v(A), 5m7w(A), 6gkk(A).
		4. Ligand: 7L2 × 3 [[[(3~{a}~{r},4~{r},6~{r},6~{a}~{r})-4-(2-Azanyl-7- Methyl-6-Oxidanylidene-1~{h}-Purin-7-Ium-9-Yl)- 2,2- Dimethyl-3~{a},4,6,6~{a}-Tetrahydrofuro[3,4-D][1, 3]dioxol-6-Yl]methoxy-Oxidanyl- Phosphoryl]oxy- Sulfanyl-Phosphoryl] [(2~{r},3~{s},4~{r},5~{r})-5-(2- Azanyl-6-Oxidanylidene- 3~{h}-Purin-9-Yl)-3,4- Bis(oxidanyl)oxolan-2-Yl]methyl hydrogen phosphate PDB codes: 5m80(A), 5m81(A),
		5. Ligand: YDZ × 3 [[[(2~{r},3~{s},4~{r},5~{r})-5-(6-Aminopurin-9-Yl)-3,4- Bis(oxidanyl)oxolan-2-Yl]methoxy-Oxidanyl- Phosphoryl]oxy-Sulfanyl-Phosphoryl] [(2~{r},3~{r}, 4~{r},5~{r})-5-(2-Azanyl-7-Methyl-6-Oxidanyl- Purin-7- Ium-9-Yl)-4-Methoxy-3-Oxidanyl-Oxolan-2-Yl]methyl hydrogen phosphate PDB codes: 5m83(A), 5m84(A).
		6. Ligand: 7LO × 2 [[[(2~{r},3~{r},4~{r},5~{r})-5-(2-Azanyl-7-Methyl-6- Oxidanyl-Purin-7-Ium-9-Yl)-4-Methoxy-3- Oxidanyl- Oxolan-2-Yl]methoxy-Oxidanyl-Phosphoryl]oxy-Selanyl- Phosphoryl] [(2~{r},3~{s},4~{r})-5- (2-Azanyl-6- Oxidanylidene-1~{h}-Purin-9-Yl)-3,4-Bis(oxidanyl) oxolan-2- Yl]methyl hydrogen phosphate PDB codes: 5m7z(A),
		7. Ligand: OYE × 2 Bn7gpppg mRNA 5' Cap analog PDB codes: 6ylr(A),
		8. Ligand: RSE × 2 [(2~{r},3~{r},4~{r},5~{r})-5-(2-Azanyl-7-Methyl-6- Oxidanylidene-1~{h}-Purin-7-Ium-9-Yl)-4-Methoxy- 3- Oxidanyl-Oxolan-2-Yl]methyl [phosphonooxy(selanyl) phosphoryl] hydrogen phosphate PDB codes: 5m7x(A),
		9. Ligand: 6G0 × 1 5'-O-[(R)-Hydroxy{[(r)-Hydroxy{[(s)- Hydroxy(phosphonooxy) phosphoryl]oxy}phosphoryl]oxy}phosphoryl]-7- Methylguanosine PDB code: 5j5o(A).
		10. Ligand: 6G6 × 1 2-Amino-9-{5-O-[(R)-{[(S)-{Dichloro[(r)- Hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy) phosphoryl]oxy}(hydroxy)phosphoryl]-2-O-Methyl- Beta-D- Ribofuranosyl}-7-Methyl-9h-Purin-7-Ium-6-Olate PDB code: 5j5y(A).
		11. Ligand: AKW × 1 [(2~{s},3~{s},4~{r},5~{r})-5-(2-Azanyl-7-Methyl-6- Oxidanylidene-3~{h}-Purin-7-Ium-9-Yl)-3,4- Bis(oxidanyl)oxolan-2-Yl]methylsulfanyl-[[[(3~{r}, 4~{s})-5-(2-Azanyl-6-Oxidanylidene-1~{h}- Purin-9-Yl)- 3,4-Bis(oxidanyl)oxolan-2-Yl]methylsulfanyl-Oxidanyl- Phosphoryl]oxy-Oxidanyl- Phosphoryl]oxy-Phosphinic acid PDB code: 5osx(A).
		12. Ligand: EI8 × 1 3-{[(4-Cyanophenyl)methyl](1-Oxo-1,2- Dihydroisoquinolin-7-Yl)sulfamoyl}benzene-1- Sulfonyl fluoride PDB code: 6u06(A).
		13. Ligand: EI9 × 1 3-{(1-Oxo-1,2-Dihydroisoquinolin-7-Yl)[(pyridin-4-Yl) methyl]sulfamoyl}benzene-1-Sulfonyl fluoride PDB code: 6u09(A).
		14. Ligand: G0Z × 1 [[[(2~{r},3~{s},4~{r},5~{r})-5-(6-Aminopurin-9-Yl)-3- [[(2~{r},3~{s},4~{r},5~{r})-5-(6-Azanyl-4,5- Dihydropurin-9-Yl)-3,4-Bis(oxidanyl)oxolan-2- Yl]methoxy-Oxidanyl-Phosphoryl]oxy-4-Oxidanyl- Oxolan- 2-Yl]methoxy-Oxidanyl-Phosphoryl]oxy-Sulfanyl- Phosphoryl] [(2~{r},3~{s},4~{r},5~{r})-5- (2-Azanyl-7- Methyl-6-Oxidanylidene-1~{h}-Purin-9-Yl)-3,4- Bis(oxidanyl)oxolan-2- Yl]methyl hydrogen phosphate PDB code: 6gkl(A).
		15. Ligand: OYW × 1 4-Cl-Bn7gpppg mRNA 5' Cap analog PDB code: 6ylv(A).
		16. Ligand: P3E × 1 [[(2~{r},3~{s},4~{r},5~{r})-5-[2-Azanyl-7-[(3- Methylphenyl)methyl]-6-Oxidanylidene-1~{h}-Purin-9- Yl]-3,4-Bis(oxidanyl)oxolan-2-Yl]methoxy-Oxidanyl- Phosphoryl] [[(2~{r},3~{s},4~{r},5~{r})-5-(2- Azanyl-6- Oxidanylidene-1~{h}-Purin-9-Yl)-3,4-Bis(oxidanyl) oxolan-2-Yl]methoxy-Oxidanyl- Phosphoryl] hydrogen phosphate PDB code: 6ylt(A).

Cluster 2 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 11 glycerin Glycerol PDB codes: 5j5o(A), 5m7w(A), 5m7x(A), 5m7z(A), 5m80(A), 5m81(A), 5m83(A), 5m84(A), 6gkj(A), 6gkk(A), 6ylv(A).

Cluster 3 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 3 glycerin Glycerol PDB codes: 5m84(A), 6gkk(A), 6gkl(A).