Ligand clusters for UniProt code P61964

Ligand clusters for P61964: WD repeat-containing protein 5 from Homo sapiens

		Top 6 (of 30) ligand clusters Cluster 1. 77 ligand types 96 ligands Cluster 2. 24 ligand types 37 ligands Cluster 3. 4 ligand types 4 ligands Cluster 4. 3 ligand types 3 ligands Cluster 5. 2 ligand types 2 ligands Cluster 6. 5 ligand types 32 ligands
Representative protein: 2h9lA

Structures

PDB		Schematic diagram
2h9lA
6u5yA
6dyaA
4ewrA
6oi3A
		more ...

Cluster 1 contains 77 ligand types (of which only 20 are listed. Click for all)

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 3 glycerin Glycerol PDB codes: 5eap(A), 6oi0(A), 6oi2(A).
		2. Ligand: DMS × 2 dimethyl sulfoxide Dimethyl sulfoxide PDB codes: 6dai(A), 6dy7(A).
		3. Ligand: NMM × 1 tilarginine (2s)-2-Amino-5-[(N-Methylcarbamimidoyl)amino]pentanoic acid PDB code: 6oi1(A).
		4. Ligand: TRS × 1 tromethamine 2-Amino-2-Hydroxymethyl-Propane-1,3-Diol PDB code: 4y7r(A).
		5. Ligand: VAL × 1 valine PDB code: 3uvm(A).
		6. Ligand: EDO × 12 1,2-Ethanediol PDB codes: 3smr(A), 3ur4(A), 4ia9(A), 4qqe(A), 4y7r(A), 5eal(A), 5eap(A), 5ear(A), 5vfc(A).
		7. Ligand: ALA-ARG-THR-MLY-GLN × 4 MLY=N-Dimethyl-Lysine. PDB codes: 2cnx(A), 2g99(A), 2g9a(A), 2h13(A).
		8. Ligand: ALA-ARG-THR-LYS-GLN-THR × 2 PDB codes: 2co0(A), 2h9m(A).
		9. Ligand: G2V × 2 6-(6,7-Dihydro-5h-Pyrrolo[1,2-A]imidazol-2-Yl)-1- Methylindoline PDB codes: 6dai(A),
		10. Ligand: 0BW × 1 Methyl 3-[(3-Methoxybenzoyl)amino]-4-(4- Methylpiperazin-1-Yl)benzoate PDB code: 3ur4(A).
		11. Ligand: 2MR × 1 N3, N4-Dimethylarginine PDB code: 6oi2(A).
		12. Ligand: 35Q × 1 N-(4-(4-Methylpiperazin-1-Yl)-3'-(Morpholinomethyl)-[1, 1'-Biphenyl]-3-Yl)-6-Oxo-4- (Trifluoromethyl)-1,6- Dihydropyridine-3-Carboxamide PDB code: 4ql1(A).
		13. Ligand: 37F × 1 N-[2-(4-Methylpiperazin-1-Yl)-5-(Quinolin-3-Yl)phenyl]- 6-Oxo-4-(Trifluoromethyl)-1,6- Dihydropyridine-3- Carboxamide PDB code: 4qqe(A).
		14. Ligand: 5ML × 1 3-Methyl-~{N}-[2-(4-Methylpiperazin-1-Yl)-5-Quinolin-3- Yl-Phenyl]benzamide PDB code: 5eal(A).
		15. Ligand: 5MN × 1 ~{N}-[5-(1~{h}-Indol-5-Yl)-2-(4-Methylpiperazin-1-Yl) phenyl]-3-Methyl-Benzamide PDB code: 5eam(A).
		16. Ligand: 5MO × 1 N-[5-(2,3-Dihydro-1-Benzofuran-5-Yl)-2-(4- Methylpiperazin-1-Yl)phenyl]-3-Methylbenzamide PDB code: 5eap(A).
		17. Ligand: 5MQ × 1 N-[5-(2,3-Dihydro-1-Benzofuran-7-Yl)-2-(4- Methylpiperazin-1-Yl)phenyl]-3-Methylbenzamide PDB code: 5ear(A).
		18. Ligand: 7DC × 1 4-[(~{E})-[4-[[[(2~{s})-2-[[(2~{s})-2-[[(2~{s})-2- [[(2~{s})-2-Azanyl-3-Oxidanyl- Propanoyl]amino]propanoyl]amino]-5-Carbamimidamido- Pentanoyl]amino]propanoyl]amino]methyl]phenyl]diazenyl ]-~{N}-[(2~{s})-3-Methyl-1-Oxidanylidene- Butan-2- Yl]benzamide PDB code: 5m23(A).
		19. Ligand: 7DU × 1 (2~{s})-2-[[(2~{s})-2-[[(2~{s})-2-Azanyl-3-Oxidanyl- Propanoyl]amino]propanoyl]amino]-5- Carbamimidamido- ~{N}-[(2~{s})-1-[[4-[(~{E})-[4- (Hydroxymethyl) phenyl]diazenyl]phenyl]methylamino]-1-Oxidanylidene- Propan-2-Yl]pentanamide PDB code: 5m25(A).
		20. Ligand: 9BA × 1 N-{(3r,6s,9s,12r)-6-Ethyl-12-Methyl-9-[3-(N'- Methylcarbamimidamido)propyl]-2,5,8,11-Tetraoxo-3- Phenyl-1,4,7,10-Tetraazacyclotetradecan-12-Yl}-2- Methylpropanamide PDB code: 5vfc(A).
+ more. Press for full list

Cluster 2 contains 24 ligand types (of which only 20 are listed. Click for all)

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 6oi3(A).
		2. Ligand: SO4 × 10 Sulfate ion PDB codes: 3ur4(A), 6e22(A), 6oi2(A), 6oi3(A), 6pg4(A), 6pg5(A), 6pg6(A), 6pgb(A), 6pgc(A), 6pgf(A).
		3. Ligand: EDO × 5 1,2-Ethanediol PDB codes: 3smr(A), 3ur4(A), 5eal(A), 5ear(A), 5vfc(A).
		4. Ligand: GLU-GLU-ILE-ASP-VAL-VAL-SER-VAL × 1 PDB code: 4y7r(A).
		5. Ligand: GLU-GLU-VAL-ASP-VAL-THR-SER-VAL-TYR × 1 PDB code: 3p4f(A).
		6. Ligand: Q0M × 1 3-{[(5-Bromo-3-Chloro-2-Hydroxyphenyl)sulfonyl]amino}- 5-(1-Cyanocyclobutyl)-2-Hydroxy-N- Methylbenzamide PDB code: 6u5y(A).
		7. Ligand: Q0S × 1 5-Bromo-2-Hydroxy-N-[3-(Methylsulfonyl)-5-(Pentafluoro- Lambda~6~-Sulfanyl)phenyl]benzene-1- Sulfonamide PDB code: 6u5m(A).
		8. Ligand: Q0Y × 1 5-Bromo-N-(5-Chloro-2-Hydroxyphenyl)-2-Methoxybenzene- 1-Sulfonamide PDB code: 6u6w(A).
		9. Ligand: Q1G × 1 5-Bromo-N-[5-(1-Cyanocyclobutyl)-2-Hydroxyphenyl]-2- Hydroxybenzene-1-Sulfonamide PDB code: 6u8o(A).
		10. Ligand: Q1J × 1 5-Bromo-N-(4-Hydroxy[1,1'-Biphenyl]-3-Yl)-2- Methoxybenzene-1-Sulfonamide PDB code: 6u80(A).
		11. Ligand: Q1M × 1 3-{[(5-Bromo-2-Methoxyphenyl)sulfonyl]amino}-5-Chloro- 2-Hydroxybenzoic acid PDB code: 6u8b(A).
		12. Ligand: Q1P × 1 3-{[(5-Bromo-2-Hydroxyphenyl)sulfonyl]amino}-5- Cyclopropyl-6-Fluoro-2-Hydroxybenzoic acid PDB code: 6u8l(A).
		13. Ligand: Q8D × 1 1-Cyclohexyl-1h-Benzotriazole-5-Carboxylic acid PDB code: 6uhz(A).
		14. Ligand: Q8G × 1 1-Cyclohexyl-1h-Benzimidazole-5-Carboxylic acid PDB code: 6uhy(A).
		15. Ligand: Q8M × 1 5-Bromo-3-Chloro-N-(1-Cyclopentyl-1h-Imidazol-4-Yl)-2- Hydroxybenzene-1-Sulfonamide PDB code: 6uik(A).
		16. Ligand: Q8P × 1 4-{[(5-Bromo-3-Chloro-2-Hydroxyphenyl)sulfonyl]amino}- 1-Cyclopentyl-N-Methyl-1h-Imidazole-2- Carboxamide PDB code: 6uif(A).
		17. Ligand: Q8S × 1 5-Bromo-3-Chloro-N-(1-Cyclopentyl-2-Methyl-1h-Imidazol- 4-Yl)-2-Hydroxybenzene-1-Sulfonamide PDB code: 6uj4(A).
		18. Ligand: QBM × 1 6-Methyl-3-(Propylsulfanyl)-1,2,4-Triazin-5-Ol PDB code: 6ujl(A).
		19. Ligand: QBP × 1 5-[4-(Trifluoromethyl)phenyl]-1h-Tetrazole PDB code: 6ujj(A).
		20. Ligand: QBS × 1 (2r)-2-(4-Chlorophenyl)-3-Oxobutanenitrile PDB code: 6ujh(A).
+ more. Press for full list

Cluster 3 contains 4 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: DMS × 1 dimethyl sulfoxide Dimethyl sulfoxide PDB code: 6dya(A).
__K		2. Metal: __K × 1 PDB code: 6iam(A).
		3. Ligand: ACE-ALA-ARG-THR-LYS × 1 ACE=Acetyl group. PDB code: 3psl(A).
		4. Ligand: ALA-ARG-THR-LYS-GLN × 1 PDB code: 2h9m(A).

Cluster 4 contains 3 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: BTB × 1 2-[Bis-(2-Hydroxy-Ethyl)-Amino]-2-Hydroxymethyl- Propane-1,3-Diol PDB code: 5eam(A).
		2. Ligand: Q1M × 1 3-{[(5-Bromo-2-Methoxyphenyl)sulfonyl]amino}-5-Chloro- 2-Hydroxybenzoic acid PDB code: 6u8b(A).
		3. Ligand: QBM × 1 6-Methyl-3-(Propylsulfanyl)-1,2,4-Triazin-5-Ol PDB code: 6ujl(A).

Cluster 5 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: EDO × 1 1,2-Ethanediol PDB code: 3smr(A).
		2. Ligand: GLU-ALA-LYS-PRO × 1 PDB code: 6iam(A).

Cluster 6 contains 5 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: SO4 × 20 Sulfate ion PDB codes: 2h9l(A), 3emh(A), 3ur4(A), 3uvk(A), 5vfc(A), 6dar(A), 6dy7(A), 6dya(A), 6oi0(A), 6oi1(A), 6oi2(A), 6pg4(A), 6pg5(A), 6pga(A), 6pgb(A), 6pgc(A), 6pgd(A), 6pge(A), 6pgf(A), 6ujh(A).
		2. Ligand: EDO × 7 1,2-Ethanediol PDB codes: 3smr(A), 4qqe(A), 5eal(A), 5eam(A), 5eap(A), 5vfc(A).
_Cl		3. Metal: _CL × 3 PDB codes: 3ur4(A), 5eal(A), 6pg6(A).
		4. Ligand: BTB × 1 2-[Bis-(2-Hydroxy-Ethyl)-Amino]-2-Hydroxymethyl- Propane-1,3-Diol PDB code: 3uvk(A).
		5. Ligand: PEG × 1 Di(hydroxyethyl)ether PDB code: 6pg7(A).