Ligand clusters for UniProt code P43490

Ligand clusters for P43490: Nicotinamide phosphoribosyltransferase from Homo sapiens

		Top 6 (of 32) ligand clusters Cluster 1. 63 ligand types 163 ligands Cluster 2. 62 ligand types 173 ligands Cluster 3. 2 ligand types 32 ligands Cluster 4. 2 ligand types 7 ligands Cluster 5. 2 ligand types 2 ligands Cluster 6. 1 ligand type 1 ligand
Representative protein: 4kfnA

Structures

PDB		Schematic diagram
4kfnA
5nsdA
4o1bA
4o0zA
4lwwA
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Cluster 1 contains 63 ligand types (of which only 20 are listed. Click for all)

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Ligand		Description
		1. Ligand: NMN × 1 Beta-Nicotinamide ribose monophosphate PDB code: 2gvg(A).
		2. Ligand: PRP × 4 5-o-phosphono-alpha-d-ribofuranosyl diphosphate 1-O-Pyrophosphono-5-O-Phosphono-Alpha-D-Ribofuranose PDB codes: 2e5c(A), 3dkj(A), 3dkl(A), 6ta0(A).
		3. Ligand: 20J × 2 diazoxide 7-Chloro-3-Methyl-2h-1,2,4-Benzothiadiazine 1,1-Dioxide PDB codes: 4lv9(A),
		4. Ligand: GOL × 2 glycerin Glycerol PDB codes: 5nsd(A),
_Mg		5. Metal: _MG × 2 PDB codes: 3dhd(A), 3dhf(A).
		6. Ligand: NCA × 1 nicotinamide Nicotinamide PDB code: 2e5d(A).
		7. Ligand: NIO × 1 niacin Nicotinic acid PDB code: 6ta0(A).
		8. Ligand: PPV × 1 pyrophosphoric acid Pyrophosphate PDB code: 6tac(A).
		9. Ligand: PO4 × 1 Phosphate ion PDB code: 2gvg(A).
		10. Ligand: DGB × 1 (2e)-N-{4-[1-(Benzenecarbonyl)piperidin-4-Yl]butyl}-3- (Pyridin-3-Yl)prop-2-Enamide PDB code: 2gvj(A).
		11. Ligand: PO4 × 51 Phosphate ion PDB codes: 4jnm(A), 4jr5(A), 4kfn(A), 4kfo(A), 4kfp(A), 4l4l(A), 4l4m(A), 4lv9(A), 4lva(A), 4lvb(A), 4lvd(B), 4lvf(A), 4lvg(A), 4lww(A), 4m6p(A), 4m6q(A), 4o0z(A), 4o10(A), 4o13(A), 4o15(A), 4o16(A), 4o18(A), 4o1a(A), 4o1b(A), 4o1c(A), 4o1d(A), 4o28(A), 4wq6(A), 5kit(A), 6b76(A), 6peb(A),
		12. Ligand: EDO × 32 1,2-Ethanediol PDB codes: 4jnm(A), 4kfo(A), 4kfp(A), 4l4l(A), 4l4m(A), 4lts(A), 4lva(A), 4lvb(A), 4lvf(A), 4lvg(A), 4lww(A), 4n9d(A), 4o16(A), 4o17(A), 4o19(A), 4o1a(A), 4o1b(A), 4o1c(A), 4o1d(A), 4o28(A), 4wq6(A).
		13. Ligand: NMN × 3 Beta-Nicotinamide ribose monophosphate PDB codes: 3dhd(A), 3dhf(A), 6tac(A).
		14. Ligand: SO4 × 4 Sulfate ion PDB codes: 5u2m(A), 5u2n(A),
		15. Ligand: DGB × 2 (2e)-N-{4-[1-(Benzenecarbonyl)piperidin-4-Yl]butyl}-3- (Pyridin-3-Yl)prop-2-Enamide PDB codes: 4o1b(A), 4o1d(A).
		16. Ligand: POP × 3 Pyrophosphate 2- PDB codes: 3dhd(A), 3dhf(A), 4m6q(A).
		17. Ligand: 1QS × 2 N-{4-[(3,5-Difluorophenyl)sulfonyl]benzyl}imidazo[1,2- A]pyridine-6-Carboxamide PDB codes: 4kfo(A), 4o28(A).
		18. Ligand: 1XC × 2 6-({4-[(3,5-Difluorophenyl)sulfonyl]benzyl}carbamoyl)- 1-(5-O-Phosphono-Beta-D- Ribofuranosyl)imidazo[1,2- A]pyridin-1-Ium PDB codes: 4l4l(A), 4o16(A).
		19. Ligand: 2P1 × 2 N-(4-{[3-(Trifluoromethyl)phenyl]sulfonyl}benzyl)-2h- Pyrazolo[3,4-B]pyridine-5-Carboxamide PDB codes: 4o13(A), 4o15(A).
		20. Ligand: BEF × 2 Beryllium trifluoride ion PDB codes: 3dhf(A), 3dkl(A).
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Cluster 2 contains 62 ligand types (of which only 20 are listed. Click for all)

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Ligand		Description
		1. Ligand: NMN × 1 Beta-Nicotinamide ribose monophosphate PDB code: 2gvg(A).
		2. Ligand: PRP × 4 5-o-phosphono-alpha-d-ribofuranosyl diphosphate 1-O-Pyrophosphono-5-O-Phosphono-Alpha-D-Ribofuranose PDB codes: 2e5c(A), 3dkj(A), 3dkl(A), 6ta0(A).
		3. Ligand: GOL × 2 glycerin Glycerol PDB codes: 5nsd(A),
		4. Ligand: 20J × 1 diazoxide 7-Chloro-3-Methyl-2h-1,2,4-Benzothiadiazine 1,1-Dioxide PDB code: 4lv9(A).
		5. Ligand: NCA × 1 nicotinamide Nicotinamide PDB code: 2e5d(A).
		6. Ligand: NIO × 1 niacin Nicotinic acid PDB code: 6ta0(A).
		7. Ligand: PPV × 1 pyrophosphoric acid Pyrophosphate PDB code: 6tac(A).
		8. Ligand: PO4 × 2 Phosphate ion PDB codes: 2gvg(A),
		9. Ligand: DGB × 1 (2e)-N-{4-[1-(Benzenecarbonyl)piperidin-4-Yl]butyl}-3- (Pyridin-3-Yl)prop-2-Enamide PDB code: 2gvj(A).
		10. Ligand: PO4 × 67 Phosphate ion PDB codes: 4jnm(A), 4jr5(A), 4kfn(A), 4kfo(A), 4kfp(A), 4l4l(A), 4l4m(A), 4lts(A), 4lv9(A), 4lva(A), 4lvb(A), 4lvd(B), 4lvf(A), 4lvg(A), 4lww(A), 4m6p(A), 4m6q(A), 4n9b(A), 4n9c(A), 4n9d(A), 4n9e(A), 4o0z(A), 4o10(A), 4o12(A), 4o13(A), 4o14(A), 4o15(A), 4o17(A), 4o18(A), 4o19(A), 4o1a(A), 4o1b(A), 4o1c(A), 4o1d(A), 4o28(A), 4wq6(A), 5kit(A), 5nsd(A), 6atb(A), 6b76(A), 6e68(A), 6peb(A), 6ta2(B).
		11. Ligand: EDO × 26 1,2-Ethanediol PDB codes: 4jr5(A), 4kfn(A), 4kfo(A), 4kfp(A), 4lts(A), 4lva(A), 4lvd(B), 4lvf(A), 4lvg(A), 4lww(A), 4n9d(A), 4n9e(A), 4o10(A), 4o13(A), 4o19(A), 4o1b(A), 4o1d(A), 4o28(A), 4wq6(A), 5kit(A),
		12. Ligand: SO4 × 7 Sulfate ion PDB codes: 5u2m(A), 5u2n(A), 5wi1(A).
		13. Ligand: NMN × 3 Beta-Nicotinamide ribose monophosphate PDB codes: 3dhd(A), 3dhf(A), 6tac(A).
		14. Ligand: DGB × 2 (2e)-N-{4-[1-(Benzenecarbonyl)piperidin-4-Yl]butyl}-3- (Pyridin-3-Yl)prop-2-Enamide PDB codes: 4o1b(A), 4o1d(A).
		15. Ligand: POP × 3 Pyrophosphate 2- PDB codes: 3dhd(A), 3dhf(A), 4m6q(A).
		16. Ligand: 1QS × 2 N-{4-[(3,5-Difluorophenyl)sulfonyl]benzyl}imidazo[1,2- A]pyridine-6-Carboxamide PDB codes: 4kfo(A), 4o28(A).
		17. Ligand: 2P1 × 2 N-(4-{[3-(Trifluoromethyl)phenyl]sulfonyl}benzyl)-2h- Pyrazolo[3,4-B]pyridine-5-Carboxamide PDB codes: 4o13(A), 4o15(A).
		18. Ligand: BEF × 2 Beryllium trifluoride ion PDB codes: 3dhf(A), 3dkl(A).
		19. Ligand: UNU × 2 Benzamide PDB codes: 3dkj(A), 3dkl(A).
		20. Ligand: 1EB × 1 N-(4-Nitrophenyl)cyclopropanecarboxamide PDB code: 4lvd(B).
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Cluster 3 contains 2 ligand types

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Ligand		Description
		1. Ligand: GOL × 5 glycerin Glycerol PDB codes: 5nsd(A), 6atb(A), 6ta0(A), 6ta2(B), 6tac(A).
		2. Ligand: EDO × 27 1,2-Ethanediol PDB codes: 4jnm(A), 4jr5(A), 4kfn(A), 4kfo(A), 4kfp(A), 4l4l(A), 4lts(A), 4lv9(A), 4lva(A), 4lvb(A), 4lvf(A), 4lww(A), 4n9d(A), 4n9e(A), 4o10(A), 4o13(A), 4o14(A), 4o16(A), 4o18(A), 4o19(A), 4o1a(A), 4o1b(A), 4o1d(A), 4o28(A), 4wq6(A), 5kit(A).

Cluster 4 contains 2 ligand types

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 5nsd(A).
		2. Ligand: EDO × 6 1,2-Ethanediol PDB codes: 4lvg(A), 4lww(A), 4n9e(A), 4o10(A), 4o16(A), 4wq6(A).

Cluster 5 contains 2 ligand types

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 5nsd(A).
		2. Ligand: EDO × 1 1,2-Ethanediol PDB code: 4o16(A).

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 5nsd(A).