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Ligand clusters for UniProt code P40306

Ligand clusters for P40306: Proteasome subunit beta type-10 from Homo sapiens

3 ligand clusters


Cluster 1. 12 ligand types 13 ligands		Cluster 2. 1 ligand type 1 ligand		Cluster 3. 1 ligand type 11 ligands

Representative protein: 6hv3H

Structures

PDB		Schematic diagram

6hv3H
6hv7H
6hv4H
6hvwH
6hvuH
		more ...

Cluster 1 contains 12 ligand types

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Ligand

Description

1. Ligand: MES × 2

2-(N-Morpholino)-Ethanesulfonic acid

PDB codes: 6hv4(H), 6hvv(H).

2. Ligand: GQH × 1

(2~{s})-~{N}-[(2~{s})-1-[[(2~{s})-1-[4-(Aminomethyl) phenyl]-4-Methylsulfonyl-Butan-2-Yl]amino]-1-
Oxidanylidene-Propan-2-Yl]-2-[[(2~{s})-2-Azido-3- Phenyl-Propanoyl]amino]-4-Methyl-Pentanamide

PDB code: 6hv5(H).

3. Ligand: GQK × 1

(2~{s})-3-(4-Methoxyphenyl)-~{N}-[(2~{s},3~{r})-4- Methyl-3,4-Bis(oxidanyl)-1-Phenyl-Pentan-2-Yl]-
2- [[(2~{s})-2-(2-Morpholin-4-Ylethanoylamino) propanoyl]amino]propanamide

PDB code: 6hv4(H).

4. Ligand: GQQ × 1

~{N}-[(2~{s})-1-[[(2~{s})-1-[[(2~{s})-1-[4- (Aminomethyl)phenyl]-4-Methylsulfonyl-Butan-2-
Yl]amino]-4-Methyl-1-Oxidanylidene-Pentan-2-Yl]amino]- 4-Methyl-1-Oxidanylidene-Pentan-2-
Yl]pyrazine-2- Carboxamide

PDB code: 6hv7(H).

5. Ligand: GQT × 1

(2~{s})-~{N}-[(2~{s})-1-[[(2~{s})-1-[4-(Aminomethyl) phenyl]-4-Methylsulfonyl-Butan-2-Yl]amino]-3-
Oxidanyl- 1-Oxidanylidene-Propan-2-Yl]-2-[[(2~{s})-2-Azido-3- Phenyl-Propanoyl]amino]-4-Methyl-
Pentanamide

PDB code: 6hva(H).

6. Ligand: GRT × 1

(2~{s})-~{N}-[2-[[(2~{s})-1-[4-(Aminomethyl)phenyl]-4- Methylsulfonyl-Butan-2-Yl]amino]-2-
Oxidanylidene- Ethyl]-2-[[(2~{s})-2-Azido-3-Phenyl-Propanoyl]amino]- 4-Methyl-Pentanamide

PDB code: 6hvs(H).

7. Ligand: GRW × 1

(2~{s})-~{N}-[(2~{s},3~{r})-1-[[(2~{s})-1-[4- (Aminomethyl)phenyl]-4-Methylsulfonyl-Butan-2-
Yl]amino]-3-Oxidanyl-1-Oxidanylidene-Butan-2-Yl]-2- [[(2~{r})-2-Azido-3-Phenyl-Propanoyl]amino]-
4-Methyl- Pentanamide

PDB code: 6hvr(H).

8. Ligand: GT5 × 1

~{N}-[(2~{s})-1-[[(2~{s})-1-[[(2~{s})-1-[4- (Aminomethyl)phenyl]-4-Methylsulfonyl-Butan-2-
Yl]amino]-3-Methoxy-1-Oxidanylidene-Propan-2- Yl]amino]-4-Methyl-1-Oxidanylidene-Pentan-2-Yl]-2-
Methyl-1,3-Thiazole-5-Carboxamide

PDB code: 6hvt(H).

9. Ligand: GT8 × 1

(2~{s})-~{N}-[(3~{s},4~{r})-1-Cyclohexyl-5-Methyl-4,5- Bis(oxidanyl)hexan-3-Yl]-3-(4-
Methoxyphenyl)-2- [[(2~{s})-2-(2-Morpholin-4-Ylethanoylamino) propanoyl]amino]propanamide

PDB code: 6hvv(H).

10. Ligand: GTW × 1

~{N}-[(2~{s})-1-[[(2~{s})-1-[[(2~{s})-1-[4- (Aminomethyl)phenyl]-4-Methylsulfonyl-Butan-2-
Yl]amino]-3-Cyclohexyl-1-Oxidanylidene-Propan-2- Yl]amino]-4-Methyl-1-Oxidanylidene-Pentan-2-Yl]-
2- Methyl-1,3-Thiazole-5-Carboxamide

PDB code: 6hvu(H).

11. Ligand: GVW-MES × 1

GVW=(2~{s})-~{N}-[(2~{s},3~{r})-1-[(4~{a}~{s},8~{a}~{s})-1, 2,3,4,4~{a},5,6,7,8,8~{a}-
Decahydronaphthalen-2-Yl]-4- Methyl-3,4-Bis(oxidanyl)pentan-2-Yl]-3-(4- Methoxyphenyl)-2-
[[(2~{s})-2-(2-Morpholin-4- Ylethanoylamino)propanoyl]amino]propanamide, MES=2-(N-Morpholino)-Ethanesulfonic acid.

PDB code: 6hvw(H).

12. Ligand: SO4 × 1

Sulfate ion

PDB code: 6hv3(H).

Ligand clusters for UniProt code P40306

Ligand clusters for P40306: Proteasome subunit beta type-10 from Homo sapiens

Structures

Cluster 1 contains 12 ligand types

Cluster 2 contains 1 ligand type

Cluster 3 contains 1 ligand type