Ligand clusters for UniProt code P34897

Ligand clusters for P34897: Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens GN=SHMT2 PE=1 SV=3

		Top 6 (of 15) ligand clusters Cluster 1. 8 ligand types 9 ligands Cluster 2. 7 ligand types 9 ligands Cluster 3. 2 ligand types 3 ligands Cluster 4. 1 ligand type 1 ligand Cluster 5. 1 ligand type 1 ligand Cluster 6. 1 ligand type 1 ligand
Representative protein: 5v7iA

Structures

PDB		Schematic diagram
5v7iA
4pvfA
6qvlA
6qvgA
5x3vA
		more ...

Cluster 1 contains 8 ligand types

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Ligand		Description
		1. Ligand: PLP × 2 pyridoxal phosphate Pyridoxal-5'-Phosphate PDB codes: 6qvg(A), 6qvl(A).
		2. Ligand: 4DW × 1 pemetrexed N-{4-[2-(2-Amino-4-Oxo-4,7-Dihydro-3h-Pyrrolo[2,3- D]pyrimidin-5-Yl)ethyl]benzoyl}-L-Glutamic acid PDB code: 6qvl(A).
		3. Ligand: DXC × 1 deoxycholic acid (3alpha,5beta,12alpha)-3,12-Dihydroxycholan-24-Oic acid PDB code: 6m5o(A).
		4. Ligand: GLY × 1 glycine PDB code: 6m5o(A).
		5. Ligand: GOL × 1 glycerin Glycerol PDB code: 4pvf(A).
		6. Ligand: 8Z1 × 1 (4r)-6-Amino-3-Methyl-4-(Propan-2-Yl)-4-[3-(Pyrrolidin- 1-Yl)-5-(Trifluoromethyl)phenyl]-1,4- Dihydropyrano[2, 3-C]pyrazole-5-Carbonitrile PDB code: 5v7i(A).
		7. Ligand: DDF × 1 5,10-Dideazatetrahydrofolic acid PDB code: 6qvg(A).
		8. Ligand: SO4 × 1 Sulfate ion PDB code: 5x3v(A).

Cluster 2 contains 7 ligand types

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Ligand		Description
		1. Ligand: GLY × 2 glycine PDB codes: 5v7i(A), 6m5o(A).
		2. Ligand: PLP × 2 pyridoxal phosphate Pyridoxal-5'-Phosphate PDB codes: 6qvg(A), 6qvl(A).
		3. Ligand: DXC × 1 deoxycholic acid (3alpha,5beta,12alpha)-3,12-Dihydroxycholan-24-Oic acid PDB code: 6m5o(A).
		4. Ligand: GOL × 1 glycerin Glycerol PDB code: 4pvf(A).
		5. Ligand: 8Z1 × 1 (4r)-6-Amino-3-Methyl-4-(Propan-2-Yl)-4-[3-(Pyrrolidin- 1-Yl)-5-(Trifluoromethyl)phenyl]-1,4- Dihydropyrano[2, 3-C]pyrazole-5-Carbonitrile PDB code: 5v7i(A).
		6. Ligand: DDF × 1 5,10-Dideazatetrahydrofolic acid PDB code: 6qvg(A).
		7. Ligand: SO4 × 1 Sulfate ion PDB code: 5x3v(A).

Cluster 3 contains 2 ligand types

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Ligand		Description
		1. Ligand: GOL × 2 glycerin Glycerol PDB codes: 5v7i(A), 6qvl(A).
		2. Ligand: PEG × 1 Di(hydroxyethyl)ether PDB code: 6qvl(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: PEG × 1 Di(hydroxyethyl)ether PDB code: 4pvf(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: PEG × 1 Di(hydroxyethyl)ether PDB code: 5v7i(A).

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: PEG × 1 Di(hydroxyethyl)ether PDB code: 5v7i(A).