Ligand clusters for UniProt code P22894

Ligand clusters for P22894: Neutrophil collagenase from Homo sapiens

		5 ligand clusters Cluster 1. 24 ligand types 51 ligands Cluster 2. 2 ligand types 5 ligands Cluster 3. 1 ligand type 23 ligands Cluster 4. 1 ligand type 25 ligands Cluster 5. 1 ligand type 24 ligands
Representative protein: 1bzsA

Structures

PDB		Schematic diagram
1bzsA
1mmbA
4qkzA
1jaoA
3dpfA
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Cluster 1 contains 24 ligand types (of which only 20 are listed. Click for all)

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Ligand		Description
_Zn		1. Metal: _ZN × 25 PDB codes: 1a85(A), 1a86(A), 1bzs(A), 1i73(A), 1i76(A), 1jan(A), 1jao(A), 1jap(A), 1jaq(A), 1jh1(A), 1jj9(A), 1kbc(A), 1mmb(A), 1mnc(A), 1zp5(A), 1zs0(A), 1zvx(A), 2oy2(A), 2oy4(A), 3dng(A), 3dpe(A), 3dpf(A), 3tt4(A), 4qkz(A), 5h8x(A).
		2. Ligand: HAE × 1 acetohydroxamic acid Acetohydroxamic acid PDB code: 3dpf(A).
		3. Ligand: AXB × 2 N-{[2-(2-Amino-3,4-Dioxocyclobut-1-En-1-Yl)-1,2,3,4- Tetrahydroisoquinolin-7-Yl]methyl}-4-Oxo- 3,5,6,8- Tetrahydro-4h-Thiopyrano[4',3':4,5]thieno[2,3- D]pyrimidine-2-Carboxamide 7,7-Dioxide PDB codes: 3dpe(A), 3dpf(A).
		4. Ligand: BSI × 2 2-(Biphenyl-4-Sulfonyl)-1,2,3,4-Tetrahydro- Isoquinoline-3-Carboxylic acid PDB codes: 1bzs(A), 1i76(A).
		5. Ligand: PRO-LEU-GLY-HOA × 2 HOA=Hydroxyamine. PDB codes: 1jan(A), 1jap(A).
		6. Ligand: 01S × 1 N-[(2r)-2-(Hydroxycarbamoyl)-4-Methylpentanoyl]-L- Alanylglycinamide PDB code: 1jaq(A).
		7. Ligand: 0D3 × 1 N-[(2s)-2-Benzyl-3-Sulfanylpropanoyl]-L- Alanylglycinamide PDB code: 1jao(A).
		8. Ligand: 0DY × 1 N~1~-(3-Aminobenzyl)-N~2~-[(2r)-2-(Hydroxycarbamoyl)-4- Methylpentanoyl]-L-Aspartamide PDB code: 1a85(A).
		9. Ligand: 0ZB × 1 N-Benzyl-N~2~-[(2r)-2-(Hydroxycarbamoyl)-4- Methylpentanoyl]-L-Alpha-Asparagine PDB code: 1a86(A).
		10. Ligand: 2NI × 1 N-{2-[(4'-Cyano-1,1'-Biphenyl-4-Yl)oxy]ethyl}-N'- Hydroxy-N-Methylurea PDB code: 1zp5(A).
		11. Ligand: 5XT × 1 ~{N}-[3,4-Bis(oxidanyl)phenyl]-4-Phenyl- Benzenesulfonamide PDB code: 5h8x(A).
		12. Ligand: 7FY × 1 ~{N}-[4,5-Bis(oxidanylidene)cyclohexen-1-Yl]-4-Phenyl- Benzenesulfonamide PDB code: 5h8x(A).
		13. Ligand: AXA × 1 (5s)-5-(2-Amino-2-Oxoethyl)-4-Oxo-N-[(3-Oxo-3,4- Dihydro-2h-1,4-Benzoxazin-6-Yl)methyl]- 3,4,5,6,7,8- Hexahydro[1]benzothieno[2,3-D]pyrimidine-2-Carboxamide PDB code: 3dng(A).
		14. Ligand: BAT × 1 4-(N-Hydroxyamino)-2r-Isobutyl-2s-(2- Thienylthiomethyl)succinyl-L-Phenylalanine-N- Methylamide PDB code: 1mmb(A).
		15. Ligand: BBT × 1 2-Hydroxy-5-[4-(2-Hydroxy-Ethyl)-Piperidin-1-Yl]-5- Phenyl-1h-Pyrimidine-4,6-Dione PDB code: 1jj9(A).
		16. Ligand: E1S × 1 N~2~-{3-[4-(5-Methylthiophen-2-Yl)phenyl]propanoyl}-L- Alpha-Glutamine PDB code: 3tt4(A).
		17. Ligand: EIN × 1 (1s)-1-{[(4'-Methoxy-1,1'-Biphenyl-4-Yl) sulfonyl]amino}-2-Methylpropylphosphonic acid PDB code: 1zs0(A).
		18. Ligand: FIN × 1 (1r)-1-{[(4'-Methoxy-1,1'-Biphenyl-4-Yl) sulfonyl]amino}-2-Methylpropylphosphonic acid PDB code: 1zvx(A).
		19. Ligand: HLE-RIN × 1 HLE=3-Formyl-2-Hydroxy-5-Methyl-Hexanoic acid hydroxyamide, RIN=3-Amino-Azacyclotridecan-2-One. PDB code: 1kbc(A).
		20. Ligand: ILE-ALA-GLY × 1 PDB code: 2oy2(A).
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Cluster 2 contains 2 ligand types

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Ligand		Description
		1. Ligand: MES × 4 2-(N-Morpholino)-Ethanesulfonic acid PDB codes: 1zs0(A), 3tt4(A), 4qkz(A), 5h8x(A).
		2. Ligand: EPE × 1 4-(2-Hydroxyethyl)-1-Piperazine ethanesulfonic acid PDB code: 1bzs(A).

Cluster 3 contains 1 ligand type

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Ligand		Description
_Ca		1. Metal: _CA × 23 PDB codes: 1a85(A), 1a86(A), 1bzs(A), 1i73(A), 1i76(A), 1jan(A), 1jao(A), 1jap(A), 1jaq(A), 1jh1(A), 1jj9(A), 1kbc(A), 1mmb(A), 1zp5(A), 1zs0(A), 1zvx(A), 2oy2(A), 2oy4(A), 3dng(A), 3dpe(A), 3dpf(A), 4qkz(A), 5h8x(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
_Zn		1. Metal: _ZN × 25 PDB codes: 1a85(A), 1a86(A), 1bzs(A), 1i73(A), 1i76(A), 1jan(A), 1jao(A), 1jap(A), 1jaq(A), 1jh1(A), 1jj9(A), 1kbc(A), 1mmb(A), 1mnc(A), 1zp5(A), 1zs0(A), 1zvx(A), 2oy2(A), 2oy4(A), 3dng(A), 3dpe(A), 3dpf(A), 3tt4(A), 4qkz(A), 5h8x(A).

Cluster 5 contains 1 ligand type

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Ligand		Description
_Ca		1. Metal: _CA × 24 PDB codes: 1a85(A), 1a86(A), 1bzs(A), 1i73(A), 1i76(A), 1jan(A), 1jao(A), 1jap(A), 1jaq(A), 1jh1(A), 1jj9(A), 1kbc(A), 1mmb(A), 1mnc(A), 1zp5(A), 1zs0(A), 1zvx(A), 2oy2(A), 2oy4(A), 3dng(A), 3dpe(A), 3dpf(A), 4qkz(A), 5h8x(A).