Ligand clusters for UniProt code P22748

Ligand clusters for P22748: Carbonic anhydrase 4 from Homo sapiens

		Top 6 (of 8) ligand clusters Cluster 1. 12 ligand types 25 ligands Cluster 2. 1 ligand type 1 ligand Cluster 3. 1 ligand type 1 ligand Cluster 4. 2 ligand types 2 ligands Cluster 5. 2 ligand types 6 ligands Cluster 6. 1 ligand type 5 ligands
Representative protein: 1zncA

Structures

PDB		Schematic diagram
1zncA
3f7bA
3fw3A
5jn8A
5jncA
		more ...

Cluster 1 contains 12 ligand types

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
_Zn		1. Metal: _ZN × 11 PDB codes: 1znc(A), 3f7b(A), 3f7u(A), 3fw3(A), 5ipz(A), 5jn8(A), 5jn9(A), 5jna(A), 5jnc(A), 5ku6(A).
		2. Ligand: 6LH × 1 mafenide 4-(Aminomethyl)benzene-1-Sulfonamide PDB code: 5jnc(A).
		3. Ligand: AZM × 1 acetazolamide 5-Acetamido-1,3,4-Thiadiazole-2-Sulfonamide PDB code: 5jn8(A).
		4. Ligand: ETS × 1 dorzolamide (4s-Trans)-4-(Ethylamino)-5,6-Dihydro-6-Methyl-4h- Thieno(2,3-B)thiopyran-2-Sulfonamide-7,7-Dioxide PDB code: 3fw3(A).
		5. Ligand: MZM × 1 methazolamide N-(3-Methyl-5-Sulfamoyl-1,3,4-Thiadiazol-2(3h)- Ylidene)acetamide PDB code: 5ku6(A).
		6. Ligand: TOR × 1 topiramate [(3as,5ar,8ar,8bs)-2,2,7,7-Tetramethyltetrahydro-3ah- Bis[1,3]dioxolo[4,5-B:4',5'-D]pyran-3a- Yl]methyl sulfamate PDB code: 5jna(A).
		7. Ligand: SO4 × 4 Sulfate ion PDB codes: 1znc(A), 3fw3(A), 5jn8(A).
		8. Ligand: 6CC × 1 5-(2-Amino-1,3-Thiazol-4-Yl)-2-Chlorobenzene-1- Sulfonamide PDB code: 5ipz(A).
		9. Ligand: ACT × 1 Acetate ion PDB code: 5jnc(A).
		10. Ligand: AG4 × 1 N-(3-Methoxypropyl)-2-(Phenylsulfanyl)-5- Sulfamoylpyridine-3-Carboxamide PDB code: 3f7u(A).
		11. Ligand: AG5 × 1 N-(2-Phenylethyl)-2-(Phenylsulfanyl)-5- Sulfamoylpyridine-3-Carboxamide PDB code: 3f7b(A).
		12. Ligand: EZL × 1 6-Ethoxy-1,3-Benzothiazole-2-Sulfonamide PDB code: 5jn9(A).

Cluster 2 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: AG5 × 1 N-(2-Phenylethyl)-2-(Phenylsulfanyl)-5- Sulfamoylpyridine-3-Carboxamide PDB code: 3f7b(A).

Cluster 3 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GLC × 1 d-glucose Alpha-D-Glucopyranose PDB code: 3fw3(A).

Cluster 4 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 5jnc(A).
		2. Ligand: SO4 × 1 Sulfate ion PDB code: 5jn8(A).

Cluster 5 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: SO4 × 5 Sulfate ion PDB codes: 5jn8(A), 5jn9(A), 5jna(A), 5jnc(A), 5ku6(A).
		2. Ligand: ACT × 1 Acetate ion PDB code: 5jn8(A).

Cluster 6 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 5 glycerin Glycerol PDB codes: 5jn8(A), 5jn9(A), 5jna(A), 5jnc(A), 5ku6(A).