Ligand clusters for UniProt code P22188

Ligand clusters for P22188: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase from Escherichia coli (strain K12)

		Top 6 (of 7) ligand clusters Cluster 1. 11 ligand types 18 ligands Cluster 2. 4 ligand types 4 ligands Cluster 3. 2 ligand types 7 ligands Cluster 4. 1 ligand type 1 ligand Cluster 5. 2 ligand types 3 ligands Cluster 6. 1 ligand type 2 ligands
Representative protein: 1e8cA

Structures

PDB		Schematic diagram
1e8cA
7b6jA
7b6iA
7b6mA
7b61A
		more ...

Cluster 1 contains 11 ligand types

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: IPA × 5 isopropyl alcohol Isopropyl alcohol PDB codes: 7b6j(A), 7b6k(A), 7b6o(A), 7b6p(A),
		2. Ligand: DMS × 3 dimethyl sulfoxide Dimethyl sulfoxide PDB codes: 7b60(A), 7b68(A), 7b6k(A).
		3. Ligand: EDO × 2 1,2-Ethanediol PDB codes: 7b53(A), 7b6j(A).
		4. Ligand: 9JT × 1 ~{N}-Phenyl-2-Selanyl-Benzamide PDB code: 7b6p(A).
		5. Ligand: JHP × 1 4-Chloro-N-Cyclopentyl-1-Methyl-1h-Pyrazole-3- Carboxamide PDB code: 7b9e(A).
		6. Ligand: LVV × 1 4-[(4-Methylphenyl)methyl]-1,4-Thiazinane 1,1-Dioxide PDB code: 7b68(A).
		7. Ligand: O3D × 1 4-[(Furan-2-Yl)methyl]-1lambda~6~,4-Thiazinane-1,1- Dione PDB code: 7b60(A).
		8. Ligand: SZ2 × 1 5-Cyclohexyl-3-(Pyridin-4-Yl)-1,2,4-Oxadiazole PDB code: 7b6k(A).
		9. Ligand: SZB × 1 Succinimide PDB code: 7b6j(A).
		10. Ligand: SZK × 1 (1-Ethyl-1h-Benzoimidazol-2-Yl)-Furan-2-Ylmethyl-Aminee PDB code: 7b6l(A).
		11. Ligand: T3Z × 1 (R)-N-(1-Cyclopropylethyl)-6-Methylpicolinamide PDB code: 7b61(A).

Cluster 2 contains 4 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: LVV × 1 4-[(4-Methylphenyl)methyl]-1,4-Thiazinane 1,1-Dioxide PDB code: 7b68(A).
		2. Ligand: O3D × 1 4-[(Furan-2-Yl)methyl]-1lambda~6~,4-Thiazinane-1,1- Dione PDB code: 7b60(A).
		3. Ligand: SZB × 1 Succinimide PDB code: 7b6j(A).
		4. Ligand: UAG-API × 1 UAG=Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine-D- Glutamate, API=2,6-Diaminopimelic acid. PDB code: 1e8c(A).

Cluster 3 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: CIT × 4 citric acid Citric acid PDB codes: 7b61(A), 7b6i(A), 7b6k(A), 7b6p(A).
		2. Ligand: EDO × 3 1,2-Ethanediol PDB codes: 7b53(A), 7b6m(A), 7b6n(A).

Cluster 4 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: SYQ × 1 (S)-N-(1-Cyclopropylethyl)-6-Methylpicolinamide PDB code: 7b61(A).

Cluster 5 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: IPA × 2 isopropyl alcohol Isopropyl alcohol PDB codes: 7b61(A), 7b6l(A).
		2. Ligand: DMS × 1 dimethyl sulfoxide Dimethyl sulfoxide PDB code: 7b68(A).

Cluster 6 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: IPA × 2 isopropyl alcohol Isopropyl alcohol PDB codes: 7b60(A), 7b61(A).