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EBI
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PDBsum
Ligand clusters for UniProt code P14416
Ligand clusters for P14416: D(2) dopamine receptor OS=Homo sapiens GN=DRD2 PE=1 SV=2
4 ligand clusters
Cluster 1.
3 ligand types
5 ligands
Cluster 2.
2 ligand types
9 ligands
Cluster 3.
2 ligand types
5 ligands
Cluster 4.
1 ligand type
2 ligands
Representative protein: 6c38A
Structures
PDB
Schematic diagram
6c38
A
6cm4
A
6luq
A
7jvr
R
6vms
R
Cluster 1 contains 3 ligand types
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Ligand
Description
1. Ligand:
08Y × 2
bromocriptine
Bromoergocryptine
PDB codes:
6vms
(R),
7jvr
(R).
2. Ligand:
8NU × 2
risperidone
3-[2-[4-(6-Fluoranyl-1,2-Benzoxazol-3-Yl)piperidin-1- Yl]ethyl]-2-Methyl-6,7,8,9-
Tetrahydropyrido[1,2- A]pyrimidin-4-One
PDB codes:
6c38
(A),
6cm4
(A).
3. Ligand:
GMJ × 1
haloperidol
4-[4-(4-Chlorophenyl)-4-Hydroxypiperidin-1-Yl]-1-(4- Fluorophenyl)butan-1-One
PDB code:
6luq
(A).
Cluster 2 contains 2 ligand types
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Ligand
Description
1. Ligand:
OLA × 7
Oleic acid
PDB codes:
6c38
(A),
6cm4
(A),
6luq
(A),
2. Ligand:
PEG × 2
Di(hydroxyethyl)ether
PDB codes:
6c38
(A),
6cm4
(A).
Cluster 3 contains 2 ligand types
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Ligand
Description
1. Ligand:
OLA × 3
Oleic acid
PDB codes:
6c38
(A),
6cm4
(A),
6luq
(A).
2. Ligand:
PEG × 2
Di(hydroxyethyl)ether
PDB codes:
6c38
(A),
6cm4
(A).
Cluster 4 contains 1 ligand type
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Ligand
Description
1. Ligand:
PEG × 2
Di(hydroxyethyl)ether
PDB codes:
6c38
(A),
6cm4
(A).