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Ligand clusters for UniProt code P14416

Ligand clusters for P14416: D(2) dopamine receptor OS=Homo sapiens GN=DRD2 PE=1 SV=2

4 ligand clusters
Cluster 1.
3 ligand types
5 ligands
Cluster 2.
2 ligand types
9 ligands
Cluster 3.
2 ligand types
5 ligands
Cluster 4.
1 ligand type
2 ligands
Representative protein: 6c38A  
JSmol
 

Structures

PDB   Schematic diagram
6c38A    
6cm4A    
6luqA    
7jvrR    
6vmsR    

 

 Cluster 1 contains 3 ligand types

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Ligand Description


 
1. Ligand: 08Y × 2
bromocriptine
Bromoergocryptine
PDB codes: 6vms(R), 7jvr(R).


 
2. Ligand: 8NU × 2
risperidone
3-[2-[4-(6-Fluoranyl-1,2-Benzoxazol-3-Yl)piperidin-1- Yl]ethyl]-2-Methyl-6,7,8,9-
Tetrahydropyrido[1,2- A]pyrimidin-4-One
PDB codes: 6c38(A), 6cm4(A).


 
3. Ligand: GMJ × 1
haloperidol
4-[4-(4-Chlorophenyl)-4-Hydroxypiperidin-1-Yl]-1-(4- Fluorophenyl)butan-1-One
PDB code: 6luq(A).

 

 Cluster 2 contains 2 ligand types

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Ligand Description


 
1. Ligand: OLA × 7
Oleic acid
PDB codes: 6c38(A), 6cm4(A), 6luq(A),


 
2. Ligand: PEG × 2
Di(hydroxyethyl)ether
PDB codes: 6c38(A), 6cm4(A).

 

 Cluster 3 contains 2 ligand types

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Ligand Description


 
1. Ligand: OLA × 3
Oleic acid
PDB codes: 6c38(A), 6cm4(A), 6luq(A).


 
2. Ligand: PEG × 2
Di(hydroxyethyl)ether
PDB codes: 6c38(A), 6cm4(A).

 

 Cluster 4 contains 1 ligand type

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Ligand Description


 
1. Ligand: PEG × 2
Di(hydroxyethyl)ether
PDB codes: 6c38(A), 6cm4(A).

 

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