_EC 7.4.2.12 ABC-type cystine transporter. 0 PDB entries  
EC 7.-.-.- Translocases. [2,261 PDB entries]
EC 7.4.-.- Catalysing the translocation amino acids and peptides. [120 PDB entries]
EC 7.4.2.- Linked to the hydrolysis of a nucleoside triphosphate. [120 PDB entries]
EC 7.4.2.12 ABC-type cystine transporter. [-]

Reaction: (1) L-cystine(out) + Atp + H2O = L-cystine(in) + adp + phosphate + H(+). (2) D-cystine(out) + Atp + H2O = D-cystine(in) + adp + phosphate + H(+).
 

L-cystine(out)
+
ATP
+ H2O
= L-cystine(in)
+
ADP
+
phosphate
+ H(+)
D-cystine(out)
+
ATP
+ H2O
= D-cystine(in)
+
ADP
+
phosphate
+ H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): cystine Abc transporter. cystine transporting ATPase.
Comments: ABC-type (ATP-binding cassette-type) transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high affinity import of trace cystine. The enzyme from Escherichia coli K-12 can import both isomers of cystine and a variety of related molecules including djenkolate, lanthionine, diaminopimelate and homocystine.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.7.4.2.12