_EC 2.3.1.313 NAD-dependent lipoamidase.

0 PDB entries

EC 2.-.-.- Transferases. [47,784 PDB entries] EC 2.3.-.- Acyltransferases. [6,129 PDB entries] EC 2.3.1.- Transferring groups other than amino-acyl groups. [3,260 PDB entries] EC 2.3.1.313 NAD-dependent lipoamidase. [-]

Reaction:		N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-lipoyl-ADP-D- ribose + nicotinamide + L-lysyl-[protein].
		N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-lipoyl-ADP-D- ribose + nicotinamide + L-lysyl-[protein] Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments:		The enzyme, a member of the sirtuin family, removes the lipoyl group from the dihydrolipoamide acyltransferase (E2) component of 2-oxo acid dehydrogenase complexes such as Ec 1.2.1.104. The enzyme often has additional activities and can remove other modifications of lysine residues such as acetyl and biotinyl groups. cf. Ec 3.5.1.138.
Links:		[IntEnz]   [ExPASy]   [KEGG]

There are no PDB entries in enzyme class E.C.2.3.1.313