_EC 1.17.99.10 steroid C-25 hydroxylase. 0 PDB entries  
EC 1.-.-.- Oxidoreductases. [21,435 PDB entries]
EC 1.17.-.- Acting on Ch or CH2 groups. [557 PDB entries]
EC 1.17.99.- With other acceptors. [16 PDB entries]
EC 1.17.99.10 steroid C-25 hydroxylase. [-]

Reaction: cholest-4-en-3-one + A + H2O = 25-hydroxycholest-4-en-3-one + AH2.
 


cholest-4-en-3-one
+
+ H2O
= 25-hydroxycholest-4-en-3-one
+ AH2
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): cholesterol C-25 dehydrogenase. steroid C-25 dehydrogenase.
Comments: The enzyme, characterized from the bacterium Sterolibacterium denitrificans, participates in the anaerobic degradation of cholesterol. The enzyme can accept several substrates including vitamin D3. The enzyme contains a bis(guanylyl molybdopterin) cofactor, five [Fe-S] clusters, and one heme b. cf. Ec 1.14.99.38.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.1.17.99.10