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| _EC 1.17.99.10 steroid C-25 hydroxylase. | 0 PDB entries | |||||||||||||||
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| Reaction: | cholest-4-en-3-one + A + H2O = 25-hydroxycholest-4-en-3-one + AH2. | ||||||||||
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| Other name(s): | cholesterol C-25 dehydrogenase. steroid C-25 dehydrogenase. | ||||||||||
| Comments: | The enzyme, characterized from the bacterium Sterolibacterium denitrificans, participates in the anaerobic degradation of cholesterol. The enzyme can accept several substrates including vitamin D3. The enzyme contains a bis(guanylyl molybdopterin) cofactor, five [Fe-S] clusters, and one heme b. cf. Ec 1.14.99.38. | ||||||||||
| Links: |
[IntEnz]
[ExPASy]
[KEGG]
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There are no PDB entries in enzyme class E.C.1.17.99.10