The enzyme catalyses the oxidative coupling of a variety of aromatic phenols by using the oxidant H2O2 as a cofactor. The enzyme binds two structural calcium ions and a catalytic Fe-heme cofactor PMID12668462.
CA 502 A IN THE RESTING STATE ENZYME
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Representative PDB structure for CA 502 A in the resting state enzyme | |
| PDB code | 1arp | |
| Metal Type in the PDB | calcium | |
| Residue name of the metal in the PDB | CA | |
| Residue number of the metal in the PDB | 347 | |
| Chain of the metal in the PDB | _ | |
| Atom name of the metal in the PDB | CA | |
| Download the coordinates file of the metal site | NOTES ON PDB: | |
| First Coordination Sphere | ||||||
| Ligand Type | Ligand Identity | Residue In MACiE | Donors | Bind Mode | Catalytic? | Notes |
| residue | SER 185 A | THR 171 A | O,OG | bidentate | No | - |
| residue | ASP 202 A | ASP 222 A | OD1,OD2 | bidentate | No | - |
| residue | THR 204 A | THR 225 A | O,OG1 | bidentate | No | - |
| residue | VAL 207 A | ILE 228 A | O | monodentate | No | - |
| residue | ASP 209 A | ASP 230 A | OD1 | monodentate | No | - |