The enzyme catalyzes the reversible interconversion of the (S)- and (R)-enantiomers of mandelate. The enzyme uses Mg2+ to perform the catalysis (PMID11456585).
CATALYTIC METAL(S)
| Metal/Site Information | |||||
| Residue in MACiE* | Atom in MACiE* | Residue Type in MACiE | Physiological Metal |
Site Type |
Function(s) |
| MG 360 x | MG | magnesium | magnesium | mononuclear | Increases acidity Coordinates substrate Electrostatic stabiliser |
*It refers to the MACiE reference pdb: 1mns
| Metal/s Properties in Resting State | ||||||
| MG 360 x | Resting state enzyme (2mnr) | |||||
| Oxidation State | 2 | |||||
| Coordination Geometry | octahedral | |||||
| Coordination Number | 6 | |||||
| Notes | - | |||||
| References |
| -Garcia-Viloca M, González-Lafont A, Lluch JM A QM/MM study of the racemization of vinylglycolate catalyzed by mandelate racemase enzyme. J Am Chem Soc. 2001 Jan 31;123(4):709-21.(MEDLINE:11456585) |
| - Some information have been also deduced from the MACiE mechanism model |