The enzyme catalyzes the addition of molecular oxygen to nonactivated hydrocarbons. It uses a haem to perform the catalytic reaction (PMID10698731).
CATALYTIC METAL(S)
| Metal/Site Information | |||||
| Residue in MACiE* | Atom in MACiE* | Residue Type in MACiE | Physiological Metal |
Site Type |
Function(s) |
| HEM 417 A | FE | iron | iron | haem | Coordinates substrate Electron relay |
*It refers to the MACiE reference pdb: 1yrc
| Metal/s Properties in Resting State | ||||||
| HEM 417 A | Resting state enzyme (1phc) | |||||
| Oxidation State | 3 | |||||
| Coordination Geometry | octahedral | |||||
| Coordination Number | 6 | |||||
| Notes | - | |||||
| References |
| -Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG The catalytic pathway of cytochrome p450cam at atomic resolution. Science. 2000 Mar 3;287(5458):1615-22.(MEDLINE:10698731) |
| - Some information have been also deduced from the MACiE mechanism model |