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PDBsum entry 9imk
Go to PDB code: 
protein dna_rna metals Protein-protein interface(s) links
Viral protein/RNA PDB id
9imk

 

 

 

 

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JSmol PyMol  
Contents
Protein chains
926 a.a.
187 a.a.
72 a.a.
585 a.a.
113 a.a.
DNA/RNA
Metals
_ZN ×16
Waters ×3
PDB id:
9imk
Name: Viral protein/RNA
Title: Sars-cov-2 replication-transcription complex has a dimer architecture (drtc) in post-capping state
Structure: RNA-directed RNA polymerase nsp12. Chain: a, h. Synonym: pol,rdrp,non-structural protein 12,nsp12. Engineered: yes. Non-structural protein 8. Chain: b, d, i, k. Synonym: nsp8. Engineered: yes. Non-structural protein 7.
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 2697049
Authors: L.M.Yan,Z.H.Rao,Z.Y.Lou
Key ref: L.M.Yan et al. Structural basis for concurrence of template recyclin RNA capping in sars-Cov-2 replication/transcription. To be published, . PubMed id: 41130208
Date:
03-Jul-24     Release date:   20-Aug-25    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
P0DTD1  (R1AB_SARS2) - 
Protein chains
P0DTD1  (R1AB_SARS2) - 
Protein chains
P0DTD1  (R1AB_SARS2) - 
Protein chains
P0DTD1  (R1AB_SARS2) - 
Protein chains
P0DTD1  (R1AB_SARS2) - 
Key:    Secondary structure

DNA/RNA chains
  ATP-U-U-A-A-A-G-G-U-U-U-A-U-A-C-C-U-U-C-C-C-A-G-G-U-A-A-C-A-A-A-C-C-A-A-C-C-A- 40 bases
  A-U-C-A-A-A-A-G-U-U-G-G-U-U-G-G-U-U-U-G-U-U-A-C-C-U-G-G-G-A-A-G-G-U-A-U-A-A-A- 46 bases
  ATP-U-U-A-A-A-G-G-U-U-U-A-U-A-C-C-U-U-C-C-C-A-G-G-U-A-A-C-A-A-A-C-C-A-A-C-C-A- 40 bases
  A-U-C-A-A-A-A-G-U-U-G-G-U-U-G-G-U-U-U-G-U-U-A-C-C-U-G-G-G-A-A-G-G-U-A-U-A-A-A- 46 bases

 Enzyme reactions 
   Enzyme class 4: Chains A, H: E.C.2.7.7.48,2.7.7.50  - RNA-directed Rna polymerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
RNA(n)
 + ribonucleoside 5'-triphosphate
 = RNA(n+1)
 + diphosphate
   Enzyme class 5: Chains E, F, L, M: E.C.3.6.4.12,3.6.4.13  - Dna helicase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + H2O = ADP + phosphate + H+
ATP
 + H2O
 = ADP
 + phosphate
 + H(+)
Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

 

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