PDBsum entry 8tkc

Viral protein/immune system

PDB id: 8tkc

Contents

Protein chains

441 a.a.

130 a.a.

129 a.a.

107 a.a.

Ligands

NAG-NAG ×24

NAG-NAG-BMA ×3

NAG-NAG-BMA-MAN-MAN ×3

NAG ×15

PDB id:

8tkc

Name:

Viral protein/immune system

Title:

Cryo-em structure of HIV-1 bg505ds-sosip.664 env trimer bound to dj85- b.01 fab

Structure:

Bg505 ds-sosip surface protein gp120. Chain: a, c, e. Synonym: env polyprotein. Engineered: yes. Mutation: yes. Bg505 ds-sosip transmembrane protein gp41. Chain: b, d, f. Synonym: env polyprotein. Engineered: yes.

Source:

Human immunodeficiency virus 1. Organism_taxid: 11676. Gene: env. Expressed in: homo sapiens. Expression_system_taxid: 9606. Homo sapiens. Organism_taxid: 9606. Expression_system_taxid: 9606

Authors:

S.Pletnev,F.Hoyt,E.Fischer,P.Kwong

Key ref:

H.Wang Broad and potent HIV-1 neutralization in fusion peptide-Primed shiv-Boosted macaques.. To be published, . PubMed id: 39471811

Date:

25-Jul-23 Release date: 28-Aug-24

Protein chains

Q2N0S6  (Q2N0S6_HV1) -  Envelope glycoprotein gp160 from Human immunodeficiency virus type 1

Seq: 860 a.a.

Struc: 441 a.a.*

Protein chains

Q2N0S5  (Q2N0S5_HV1) -  Envelope glycoprotein gp160 from Human immunodeficiency virus type 1

Seq: 860 a.a.

Struc: 130 a.a.*

Protein chains

No UniProt id for this chain

Struc: 129 a.a.

Protein chains

No UniProt id for this chain

Struc: 107 a.a.

* PDB and UniProt seqs differ at 5 residue positions (black crosses)