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PDBsum entry 8pgo

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protein ligands metals links
Antimicrobial protein PDB id
8pgo

 

 

 

 

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Contents
Protein chain
232 a.a.
Ligands
YUQ
Metals
_ZN ×2
Waters ×353
PDB id:
8pgo
Name: Antimicrobial protein
Title: Crystal structure of the metallo-beta-lactamase vim1 with 3183
Structure: Beta-lactamase vim-1. Chain: a. Synonym: class b carbapenemase vim-1,metallo-beta-lactamase,metallo- beta-lactamase vim-1,metallobeta-lactamase,subclass b1 metallo-beta- lactamase vim-1,vim-1,vim-1 metallo-beta-lactamase,vim-1 protein. Engineered: yes
Source: Pseudomonas aeruginosa. Organism_taxid: 287. Gene: blavim, blavim-1, caz10_38240, caz10_38245. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41
Resolution:
1.14Å     R-factor:   0.126     R-free:   0.135
Authors: K.Calvopina,J.Brem,A.J.M.Farley,M.D.Allen,C.J.Schofield
Key ref: K.Calvopina et al. Crystal structure of the metallo-Beta-Lactamase vim1 3183. To be published, .
Date:
18-Jun-23     Release date:   10-Jul-24    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Q9XAY4  (Q9XAY4_PSEAI) -  beta-lactamase from Pseudomonas aeruginosa
Seq:
Struc:
266 a.a.
232 a.a.
Key:    Secondary structure

 Enzyme reactions 
   Enzyme class: E.C.3.5.2.6  - beta-lactamase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Penicillin Biosynthesis and Metabolism
      Reaction: a beta-lactam + H2O = a substituted beta-amino acid
      Cofactor: Zn(2+)

 

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