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PDBsum entry 8h2a
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Oxidoreductase
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PDB id
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8h2a
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PDB id:
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| Name: |
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Oxidoreductase
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Title:
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Crystal structure of alcohol dehydrogenase from formosa agariphila
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Structure:
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Alcohol dehydrogenase. Chain: a, b, c, d, e, f, g, h. Engineered: yes
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Source:
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Formosa agariphila. Organism_taxid: 320324. Strain: dsm 15362 / kctc 12365 / lmg 23005 / kmm 3901 / m-2alg 35-1. Gene: bn863_21030. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
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Resolution:
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2.50Å
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R-factor:
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0.226
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R-free:
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0.278
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Authors:
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S.Brott,U.T.Bornscheuer,K.H.Nam
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Key ref:
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S.Brott
et al.
Crystal structure of alcohol dehydrogenase from formo agariphila.
To be published,
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Date:
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05-Oct-22
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Release date:
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18-Oct-23
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PROCHECK
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Headers
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References
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T2KM87
(T2KM87_9FLAO) -
Alcohol dehydrogenase from Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1)
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Seq:
Struc:
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370 a.a.
366 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Enzyme class:
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E.C.1.1.1.1
- alcohol dehydrogenase.
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Reaction:
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1.
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a primary alcohol + NAD+ = an aldehyde + NADH + H+
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2.
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a secondary alcohol + NAD+ = a ketone + NADH + H+
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primary alcohol
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+
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NAD(+)
Bound ligand (Het Group name = )
corresponds exactly
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=
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aldehyde
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+
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NADH
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+
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H(+)
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secondary alcohol
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+
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NAD(+)
Bound ligand (Het Group name = )
corresponds exactly
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=
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ketone
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+
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NADH
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+
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H(+)
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Cofactor:
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Zn(2+) or Fe cation
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
