PDBsum entry 7xdn

Oxidoreductase

PDB id: 7xdn

Contents

Protein chain

633 a.a.

Ligands

SF4

FES

NFS

Waters ×501

PDB id:

7xdn

Name:

Oxidoreductase

Title:

Tunnel-redesigned o2-tolerant co dehydrogenase for removal of co in real flue gas (chcodh2 a559h mutant in anaerobic condition)

Structure:

Carbon monoxide dehydrogenase 2. Chain: a. Synonym: codh 2. Engineered: yes. Mutation: yes

Source:

Carboxydothermus hydrogenoformans. Organism_taxid: 129958. Strain: atcc baa-161 / dsm 6008 / z-2901. Gene: coos2, coosii, chy_0085. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.80Å R-factor: 0.166 R-free: 0.200

Authors:

Y.Y.Heo,S.M.Kim

Key ref:

S.M.Kim et al. (2022). O2-Tolerant co dehydrogenase via tunnel redesign for removal of co from industrial flue gas. Nat catal, 5, 807. DOI: 10.1038/S41929-022-00834-Y

Date:

28-Mar-22 Release date: 19-Oct-22

Protein chain

Q9F8A8  (COOS2_CARHZ) -  Carbon monoxide dehydrogenase 2 from Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)

Seq: 636 a.a.

Struc: 633 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.1.2.7.4 - anaerobic carbon-monoxide dehydrogenase.
• Reaction: CO + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = 2 reduced [2Fe-2S]- [ferredoxin] + CO2 + 2 H⁺
• Cofactor: Fe cation; Ni(2+); Zn(2+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site