PDBsum entry 7so7

Toxin/immune system

PDB id: 7so7

Contents

Protein chains

528 a.a.

213 a.a.

218 a.a.

PDB id:

7so7

Name:

Toxin/immune system

Title:

Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of clostridium difficile toxin b

Structure:

Toxin b. Chain: a, b. Engineered: yes. Fab b1 hc. Chain: x, h. Engineered: yes. Fab b1 lc. Chain: y, l. Engineered: yes

Source:

Clostridioides difficile. Peptoclostridium difficile. Organism_taxid: 1496. Gene: tcdb, toxb. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.

Resolution:

3.59Å R-factor: 0.211 R-free: 0.258

Authors:

J.Liu

Key ref:

J.Liu et al. (2022). Novel structural insights for a pair of monoclonal antibodies recognizing non-Overlapping epitopes of th glucosyltransferase domain of clostridium difficile t. Curr res struct biol, 4, 96. PubMed id: 35469152

Date:

29-Oct-21 Release date: 11-May-22

Protein chains

P18177  (TCDB_CLODI) -  Toxin B from Clostridioides difficile

Seq: 2366 a.a.

Struc: 528 a.a.

Protein chains

No UniProt id for this chain

Struc: 213 a.a.

Protein chains

No UniProt id for this chain

Struc: 218 a.a.

Enzyme reactions

• Enzyme class 2: Chains A, B: E.C.2.4.1.- - ?????
• Enzyme class 3: Chains A, B: E.C.3.4.22.- - ?????

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.